Macroscopic Resonant Tunneling in the Presence of Low Frequency Noise

We develop a theory of macroscopic resonant tunneling of flux in a double-well potential in the presence of realistic flux noise with significant low-frequency component. The rate of incoherent flux tunneling between the wells exhibits resonant peaks, the shape and position of which reflect qualitative features of the noise, and can thus serve as a diagnostic tool for studying the low-frequency flux noise in SQUID qubits. We show, in particular, that the noise-induced renormalization of the first resonant peak provides direct information on the temperature of the noise source and the strength of its quantum component.Comment: 4 pages, 1 figur

Decoherence in adiabatic quantum computation

We have studied the decoherence properties of adiabatic quantum computation (AQC) in the presence of in general non-Markovian, e.g., low-frequency, noise. The developed description of the incoherent Landau-Zener transitions shows that the global AQC maintains its properties even for decoherence larger than the minimum gap at the anticrossing of the two lowest energy levels. The more efficient local AQC, however, does not improve scaling of the computation time with the number of qubits $n$ as in the decoherence-free case. The scaling improvement requires phase coherence throughout the computation, limiting the computation time and the problem size n.Comment: 4 pages, 2 figures, published versio

Quantum Nondemolition Charge Measurement of a Josephson Qubit

In a qubit system, the measurement operator does not necessarily commute with the qubit Hamiltonian, so that the readout process demolishes (mixes) the qubit energy eigenstates. The readout time is therefore limited by such a mixing time and its fidelity will be reduced. A quantum nondemolition readout scheme is proposed in which the charge of a flux qubit is measured. The measurement operator is shown to commute with the qubit Hamiltonian in the reduced two-level Hilbert space, even though the Hamiltonian contains non-commuting charge and flux terms.Comment: 4 pages, 3 figures, a paragraph added to describe how the scheme works in charge regim

Nonlocal mixing of supercurrents in Josephson ballistic point contact

We study coherent current states in the mesoscopic superconducting weak link simultaneously subjected to the order parameter phase difference on the contact and to the tangential to the junction interface superfluid velocity in the banks. The Josephson current-phase relation controlled by the external transport current is obtained. At phase difference close to pi the nonlocal nature of the Josephson phase-dependent current results in the appearance of two vortexlike states in the vicinity of the contact.Comment: 4 pages, 6 figures; to be published in Phys. Rev. B; e-mail: [email protected]

Effect of point-contact transparency on coherent mixing of Josephson and transport supercurrents

The influence of electron reflection on dc Josephson effect in a ballistic point contact with transport current in the banks is considered theoretically. The effect of finite transparency on the vortex-like currents near the contact and at the phase difference $\phi =\pi ,$ which has been predicted recently \cite{KOSh}, is investigated. We show that at low temperatures even a small reflection on the contact destroys the mentioned vortex-like current states, which can be restored by increasing of the temperature.Comment: 6 pages, 8 Figures, Latex Fil

Utility and applications of synoptic reporting in pathology

Background: Synoptic reports in routine pathology practice provide composite documents that include information from morphology and molecular technologies. It is clear and accurate structured information and developed by incorporating standardized data elements in the form of checklist for pathology reporting. This facilitates pathologists to document their findings and ultimately improve the overall quality of pathology reports.\ud \ud Objectives: The goal of this review article is to discuss (1) the importance of synoptic reporting in pathology, (2) utility and applications, (3) its impact on pathology reporting and patient care, and (4) the challenges and barriers of implementing synoptic reporting. Pertinent literature will also be reviewed.\ud \ud Design: The synoptic reporting system provides a complete set of data elements in the form of synoptic templates or “worksheets” for pathology tumor reporting based on the World Health Organization (WHO) Classification and the College of American Pathologists (CAP) Cancer Checklists. These standards provide most updated and supplemented classification scheme, specimen details, and staging as well as prognostic information. Data from synoptic reporting tool can be imported to a relational database where they are organized and efficiently searched and retrieved. Since search and retrieval are streamlined, synoptic databases enhance basic ­science, clinical, and translational cancer research.\ud \ud Conclusion: Synoptic reporting facilitates a standard based structured method for entering the diagnostic and prognostic information in accurate and consistent fashion for a particular ­pathology specimen, thus reducing transcription services, specimen turnaround time, and typographical and transcription errors. The structured data can be imported into the Laboratory Information Service (LIS) database, which facilitates swift data access and improved communication for cancer management. Finally, these synoptic templates act as a robust medium of high-quality data from the various biospecimens, which can be shared across multiple on-going research projects to enhance basic and translational research

Corotation Resonance and Diskoseismology Modes of Black Hole Accretion Disks

We demonstrate that the corotation resonance affects only some non-axisymmetric g-mode oscillations of thin accretion disks, since it is located within their capture zones. Using a more general (weaker radial WKB approximation) formulation of the governing equations, such g-modes, treated as perfect fluid perturbations, are shown to formally diverge at the position of the corotation resonance. A small amount of viscosity adds a small imaginary part to the eigenfrequency which has been shown to induce a secular instability (mode growth) if it acts hydrodynamically. The g-mode corotation resonance divergence disappears, but the mode magnitude can remain largest at the place of the corotation resonance. For the known g-modes with moderate values of the radial mode number and axial mode number (and any vertical mode number), the corotation resonance lies well outside their trapping region (and inside the innermost stable circular orbit), so the observationally relevant modes are unaffected by the resonance. The axisymmetric g-mode has been seen by Reynolds & Miller in a recent inviscid hydrodynamic accretion disk global numerical simulation. We also point out that the g-mode eigenfrequencies are approximately proportional to m for axial mode numbers |m|>0.Comment: 16 pages, no figures. Submitted to The Astrophysical Journa

First Order Quantum Phase Transition in Adiabatic Quantum Computation

We investigate the connection between local minima in the problem Hamiltonian and first order quantum phase transitions during an adiabatic quantum computation. We demonstrate how some properties of the local minima can lead to an extremely small gap that is exponentially sensitive to the Hamiltonian parameters. Using perturbation expansion, we derive an analytical formula that can not only predict the behavior of the gap, but also provide insight on how to controllably vary the gap size by changing the parameters. We show agreement with numerical calculations for a weighted maximum independent set problem instance.Comment: 4 pages, 3 figures, published final versio

Role of Single Qubit Decoherence Time in Adiabatic Quantum Computation

We have studied numerically the evolution of an adiabatic quantum computer in the presence of a Markovian ohmic environment by considering Ising spin glass systems with up to 20 qubits independently coupled to this environment via two conjugate degrees of freedom. The required computation time is demonstrated to be of the same order as that for an isolated system and is not limited by the single-qubit decoherence time $T_2^*$, even when the minimum gap is much smaller than the temperature and decoherence-induced level broadening. For small minimum gap, the system can be described by an effective two-state model coupled only longitudinally to environment.Comment: 4 pages, 3 figures, published versio