96 research outputs found

    User Interface Design in Virtual Reality Research

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    Thesis Statement The primary objective of this research is to develop and investigate a user interface that supports learning to be implemented in the virtual reality application Anatomy Builder VR, an ongoing project from the Department of Visualization. Through the conception of this interface, we will explore the research question “how can user interface design in virtual reality applications support learning and engagement?”. Theoretical Framework Through the use of iterative design, we will develop an interface to be implemented in the virtual reality application Anatomy Builder VR.To accomplish this, we will create several prototypes to be evaluated by a focus group before implementing a high fidelity interface into the application. The three prototypes will be used to conduct a user study that will improve the quality and functionality of the final interface as a whole. Project Description Effective user interface design is extremely important when creating an application focused on learning. If the application’s interface is misleading, the user will either incorrectly learn the information or stop using the application altogether. For this reason, we will center our research on the question “how can user interface design in virtual reality applications support learning and engagement?”. Expected outcomes include designing a user interface that will provide an intuitive and engaging learning experience. Our interface will be implemented intoAnatomy Builder VR, an application that allows users to assemble a human or canine skeleton while learning comparative anatomy. Anatomy Builder VR is a current collaborative project between Department of Visualization and Department of Veterinary Integrative Biosciences. We will investigate how our design impacts the user’s anatomy learning experience

    Functional Characterisation of Candida Glabrata Open Reading Frames with no Orthologue in Saccharomyces Cerevisiae

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    Candida glabrata is a significant and increasingly common pathogen of humans yet its mechanism of virulence remains unclear. Comparative genomic studies revealed that C. glabrata is more closely related to the non-pathogenic yeast Saccharomyces cerevisiae and that both these genomes are distinct from C. albicans. In order to explore C. glabrata virulence attributes, C. glabrata ORFs with no orthologue in S. cerevisiae were studied since these ORFs may have accompanied the adaptation of C. glabrata to the human host. Reciprocal best hit searches identified C. glabrata ORFs with no S. cerevisiae orthologue. A barcoded deletion library targeting 65 C. glabrata-specific ORFs was constructed. To functionally characterise the deletion library, mutants were tested for fitness and phenotypically screened to identify gene products required for growth in response to biologically relevant stresses. As such, novel phenotypes associated with the deletion of previously uncharacterised ORFs were uncovered. Mutants were also tested for infection-related properties including biofilm formation, antifungal agent susceptibility and for virulence in a Drosophila melanogaster infection model, resulting in the identification of two C. glabrata-specific ORFs, CAGL0K05687g and CAGL0H01749g, which were required for virulence. Three ORFs with notable phenotypes were taken forward for further characterisation. An adapted genome-wide synthetic genetic interaction approach was used to create genetic interaction networks for C. glabrata ORFs over-expressed in S. cerevisiae. Genetic interaction analysis of a C. glabrata chromatin remodeler CAGL0D05434g revealed a role for this ORF in metal ion homeostasis and DNA damage repair. Genetic interaction profiling for an oxidoreductase encoded by CAGL0K05687g was used to reveal mechanisms related to transport by which this ORF may be required for virulence

    87th Legislature of Texas

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    Report from the Sunset Commission regarding the Texas Commission on Fire Protection, including the Commission's decisions and the final actions taken by the Texas Legislature, along with information from the original staff report, such as the need for, performance by, and improvements to the Texas Commission on Fire Protection

    87th Legislature of Texas

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    Report from the Sunset Commission regarding the Texas Commission on Fire Protection, including decisions on statutory recommendations for the Texas Legislature and management recommendations for the agency, as well as information from the original staff report, such as the need for, performance by, and improvements to the Texas Commission on Fire Protection

    87th Legislature of Texas

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    Report from the Sunset Commission regarding the Teacher Retirement System of Texas, including the Commission's decisions and the final actions taken by the Texas Legislature, along with information from the original staff report, such as the need for, performance by, and improvements to the Teacher Retirement System of Texas

    87th Legislature of Texas

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    Report from the Sunset Commission regarding the Texas Racing Commission, including decisions on statutory recommendations for the Texas Legislature and management recommendations for the agency, as well as information from the original staff report, such as the need for, performance by, and improvements to the Texas Racing Commission

    87th Legislature of Texas

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    Report from the Sunset Commission regarding the Anatomical Board of the State of Texas, including the Commission's decisions and the final actions taken by the Texas Legislature, along with information from the original staff report, such as the need for, performance by, and improvements to the Anatomical Board of the State of Texas
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