89 research outputs found
Steroid treatment increases the recurrence of radiation‐induced organizing pneumonia after breast‐conserving therapy
A systematic review of validated methods for identifying pulmonary fibrosis and interstitial lung disease using administrative and claims data
Australian Idiopathic Pulmonary Fibrosis Registry: Vital lessons from a national prospective collaborative project
Incidence and classification of pediatric diffuse parenchymal lung diseases in Germany
<p>Abstract</p> <p>Background</p> <p>Diffuse parenchymal lung diseases (DPLD) in children represent a rare and heterogeneous group of chronic pulmonary disorders. Despite substantial advances in genetics and pathomechanisms, these often lethal diseases are still under-diagnosed. This is due to the fact that (i) the incidence is low, and (ii) clinical presentation, (iii) disease classification and (iv) specific treatment options are largely unknown.</p> <p>Methods</p> <p>Here we systematically assessed the incidence, the presentation, the diagnostic yield and treatments of pediatric DPLD in Germany, using the Surveillance Unit for Rare Paediatric Disorders (ESPED).</p> <p>Results</p> <p>The incidence of DPLD was 1.32 new cases per 1 million of children per year. The majority of these children were diagnosed within the first year of life. Overall survival was 87%. Using centralized data entry and stratification tools, the patients were categorized into an advanced classification system based on diagnostic algorithms, including clinical presentations, genetics and/or histology. Combining molecular and clinical information, this survey provides an etiological overview and specific diagnostic recommendations for children with DPLD.</p> <p>Conclusions</p> <p>Standardized surveys and systematic classifications are valuable tools for the clinical handling of children with DPLD and aim to improve the disease understanding and the prognosis of these rare detrimental lung diseases.</p
Clinical and functional outcomes in Middle Eastern patients with idiopathic pulmonary fibrosis
Effect of Muc5b promoter polymorphism on disease predisposition and survival in idiopathic interstitial pneumonias
Prognostic significance of fibroblastic foci in usual interstitial pneumonia and non-specific interstitial pneumonia
Differential distribution of lymphatic clearance between upper and lower regions of the lung
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