31 research outputs found
Pilot production of ulvans with different molecular weights from the seaweed <i>Ulva</i> sp., and their effects on hyaluronan and collagen production in cultured human dermal fibroblasts
International audienc
Production d’ulvanes de différents poids moléculaires provenant de l'algue <i>Ulva</i> sp., et leurs effets sur la production d'hyaluronane et de collagène par des fibroblastes cutanés humains
International audienc
Evaluation of the anticoagulant potential of polysaccharide-rich fractions extracted from macroalgae
International audienceThe aim of this study was to evaluate the potential anticoagulant activity of sulphated polysaccharide-containing extracts of six french edible marine macroalgae. Aqueous extracts of brown (Himanthalia elongata, Laminaria digitata, Ascophyllum nodosum, Fucus vesiculosus), green (Ulva lactuca) and red (Chondrus crispus) macroalgae were prepared and their biochemical properties were determined, including major biomolecules, sulphate and ash contents. The anticoagulant activity of each extract was investigated using different scales from the specific antithrombin-dependent pathway (anti-Xa and anti-IIa) to the intrinsic and/or common (Activated Partial Thromboplastin Time, APTT), extrinsic (Prothrombin Time, PT) or common (Thrombin Time, TT) anticoagulant pathways, and compared with those of commercial anticoagulants, heparin and Lovenox®. Laminaria digitata, Fucus vesiculosus and Chondrus crispus extracts showed a significant APTT anticoagulant capacity, only 5-fold lower than that of Lovenox®, which is a pure low molecular weight heparin used as an anticoagulant agent to prevent pulmonary embolism in patients undergoing surgery
Polysaccharides sulfatés provenant de macro-algues vertes type Ulva sp. et leurs utilisations pour la régulation des troubles de la coagulation
Anticoagulant activity of sulfated polysaccharide-rich macroalgae extracts
International audienc