Predator- Prey Interaction In Plant –Associated Ecosystems. Effect On Plant Fitness And Trophic Cascade

Predator-prey interactions in plant-associated ecosystems play a crucial role in shaping ecosystem dynamics and stability. This study provides a comprehensive overview of the implications of these interactions, highlighting the intricate web of relationships among predators, herbivores, and plants. The findings underscore the importance of maintaining predator-prey interactions for ecosystem stability and functioning. Trophic cascades initiated by predator-prey interactions have been shown to regulate herbivore populations, indirectly benefiting plant communities. However, human activities can significantly impact predator populations and trophic cascades, emphasizing the need for conservation efforts to preserve these important ecological dynamics. The integration of molecular techniques and modeling approaches can enhance our understanding of trophic cascades in plant-associated ecosystems. Conservation strategies aimed at promoting predator diversity and enhancing plant fitness are essential for maintaining ecosystem stability and promoting sustainable management of plant-associated ecosystems. Further research is needed to investigate the complex dynamics of predator-prey interactions and trophic cascades, as well as to develop effective conservation strategies to preserve these important ecological dynamics

Probing the antibacterial and anticancer potential of tryptamine based mixed ligand Schiff base Ruthenium(III) complexes

Development of new chemotherapeutic agents to treat microbial infections and recurrent cancers is of pivotal importance. Metal based drugs particularly ruthenium complexes have the uniqueness and desired properties that make them suitable candidates for the search of potential chemotherapeutic agents. In this study, two mixed ligand Ru(III) complexes Ru(Cl)(2)(SB)(Phen] (RC-1) and Ru(Cl)(2)(SB)(Bipy)] (RC-2) were synthesised and characterized by elemental analysis, IR, UV-Vis, H-1, C-13 NMR spectroscopic techniques and their molecular structure was confirmed by X-ray crystallography. Antibacterial activity evaluation against two Gram-positive (S. pneumonia and E. faecalis) and four Gram-negative strains (P. aurogenosa, K. pneumoniae, S. enterica, and E. coli) revealed their moderate antibacterial activity with MIC value of >= 250 mu g/mL. Anticancer activity evaluation against a non-small lung cancer cell line (H1299) revealed the tremendous anticancer activity of these complexes which was further validated by DNA binding and docking results. DNA binding profile of the complexes studied by UV-Visible and fluorescence spectroscopy showed an intercalative binding mode with CT-DNA and an intrinsic binding constant in the range of 3.481-1.015 x 10(5) M-1. Both the complexes were also found to exert weak toxicity to human erythrocytes by haemolytic assay compared to cisplatin. Potential of these complexes as anticancer agents will be further delineated by in vivo studies