Evaluation of oral health status and quality of life of head and neck cancer patients after radiation therapy

Introduction. Neoplasm of the head and neck can be treated surgically, by radiation, chemotherapy, or using combination of these methods. In contrast to surgical and radiation treatment which mostly have a local effect, chemotherapy in addition to local have also a systemic effect. Both XRT in oral region and chemotherapy can affect oral health. The aim of this study was to assess the oral health status and quality of life in patients with head and neck cancer after receiving radiation therapy. Material and Methods. Quantitative, analytical and cross-sectional research methods along with the application of UW-QOL questionnaire version 4, were used. Seventy one patients of the outpatient facilities at two cancer hospitals in the state of Paraнba, Brazil, were included in the study. Oral health status was evaluated using the Lockhart and Clark criteria. Linear Poisson and Logistic Regression tests were applied to assess associations between the variables using a significance level of 5%. Results. Of the total number of patients, 71.83% were male, the average age was 62 years and 57.74% were non-Caucasian. The group that received dental monitoring and follow-up attained the highest (830.13) Quality of life scores, including: “pain” (93.13) and “taste” (83.07). The highest score for oral health in the group that did not receive dental monitoring and follow-up treatment was 4.08 for “oral hygiene”. Conclusion. Dental monitoring and follow-up should begin before radiation therapy, given that both the illness and methods used for the treatment negatively affect patients’ quality of life

Histological analysis of biocompatibility of ionomer cements with an acid-base reaction

The purpose of this study was to evaluate the inflammatory and cure events of acid-based reactions using glass ionomer cement used for cementation of crowns, bridges, onlays and orthodontic bands implanted in subcutaneous tissue, at different time intervals. A total of 48 male Wistar rats were used, distributed into 4 groups (n = 12), as follows: Group C (control, polyethylene), Group ME (Meron), Group KC (Ketac Cem) and Group PR (Precedent). The animals were sacrificed after time intervals of 7, 15 and 30 days, and their tissues were analyzed under an optical microscope for such events as inflammatory infiltrate, edema, necrosis, granulation tissue, multinucleated giant cells, young fibroblasts and collagen. The results was assessed using Kruskal-Wallis and Dunn's tests (p < 0.05). In the initial period, intense inflammatory infiltrate was observed for all the materials with no significant difference among them (p = 0.104). Groups PR and KC showed significant difference in relation to Group C, at 7 days (p = 0.025) and 15 days (p = 0.006). Edema and giant cells were more expressive in Group ME, differing significantly from Groups C (p = 0.023) and KC (p = 0.039), respectively, at 7 days. Group ME showed a statistically significant difference in relation to Groups PR and KC for the presence of young fibroblasts (p = 0.009) and for collagen (p = 0.002), at 7 days. Within the limits of this in vivo study, Precedent and Ketac Cem glass ionomer cements showed better tissue healing with a greater number of fibroblasts and collagen, as compared to Meron