1,447 research outputs found
Development and validation of a new methodological platform to measure behavioral, cognitive, and physiological responses to food interventions in real time
To fully understand the causes and mechanisms involved in overeating and obesity, measures of both cognitive and physiological determinants of eating behavior need to be integrated. Effectively synchronizing behavioral measures such as meal micro-structure (e.g., eating speed), cognitive processing of sensory stimuli, and metabolic parameters, can be complex. However, this step is central to understanding the impact of food interventions on body weight. In this paper, we provide an overview of the existing gaps in eating behavior research and describe the development and validation of a new methodological platform to address some of these issues. As part of a controlled trial, 76 men and women self-served and consumed food from a buffet, using a portion-control plate with visual stimuli for appropriate amounts of main food groups, or a conventional plate, on two different days, in a random order. In both sessions participants completed behavioral and cognitive tests using a novel methodological platform that measured gaze movement (as a proxy for visual attention), eating rate and bite size, memory for portion sizes, subjective appetite and portion-size perceptions. In a sub-sample of women, hormonal secretion in response to the meal was also measured. The novel platform showed a significant improvement in meal micro-structure measures from published data (13 vs. 33% failure rate) and high comparability between an automated gaze mapping protocol vs. manual coding for eye-tracking studies involving an eating test (ICC between methods 0.85; 90% CI 0.74, 0.92). This trial was registered at Clinical Trials.gov with Identifier NCT03610776
The Collective Field Theory of a Singular Supersymmetric Matrix Model
The supersymmetric collective field theory with the potential is studied, motivated by the matrix model proposed by Jevicki
and Yoneya to describe two dimensional string theory in a black hole
background. Consistency with supersymmetry enforces a two band solution. A
supersymmetric classical configuration is found, and interpreted in terms of
the density of zeros of certain Laguerre polynomials. The spectrum of the model
is then studied and is seen to correspond to a massless scalar and a majorana
fermion. The space eigenfunctions are constructed and expressed in terms of
Chebyshev polynomials. Higher order interactions are also discussed.Comment: Revtex 8 pages, Submitted to Phys. Rev. D. References and preprint
numbers have been adde
Coherent Radio Pulses From GEANT Generated Electromagnetic Showers In Ice
Radio Cherenkov radiation is arguably the most efficient mechanism for
detecting showers from ultra-high energy particles of 1 PeV and above. Showers
occuring in Antarctic ice should be detectable at distances up to 1 km. We
report on electromagnetic shower development in ice using a GEANT Monte Carlo
simulation. We have studied energy deposition by shower particles and
determined shower parameters for several different media, finding agreement
with published results where available. We also report on radio pulse emission
from the charged particles in the shower, focusing on coherent emission at the
Cherenkov angle. Previous work has focused on frequencies in the 100 MHz to 1
GHz range. Surprisingly, we find that the coherence regime extends up to tens
of Ghz. This may have substantial impact on future radio-based neutrino
detection experiments as well as any test beam experiment which seeks to
measure coherent Cherenkov radiation from an electromagnetic shower. Our study
is particularly important for the RICE experiment at the South Pole.Comment: 44 pages, 29 figures. Minor changes made, reference added, accepted
for publication in Phys. Rev.
Tissue remodelling and increased DNA damage in patients with incompetent valves in chronic venous insufficiency
Chronic venous insufficiency (CVI), in which blood return to the heart is impaired, is a prevalent condition worldwide. Valve incompetence is a complication of CVI that results in blood reflux, thereby aggravating venous hypertension. While CVI has a complex course and is known to produce alterations in the vein wall, the underlying pathological mechanisms remain unclear. This study examined the presence of DNA damage, pro-inflammatory cytokines and extracellular matrix remodelling in CVI-related valve incompetence. One hundred and ten patients with CVI were reviewed and divided into four groups according to age (<50 and â„50 years) and a clinical diagnosis of venous reflux indicating venous system valve incompetence (R) (n = 81) or no reflux (NR) (n = 29). In vein specimens (greater saphenous vein) from each group, PARP, IL-17, COL-I, COL-III, MMP-2 and TIMP-2 expression levels were determined by RT-qPCR and immunohistochemistry. The younger patients with valve incompetence showed significantly higher PARP, IL-17, COL-I, COL-III, MMP-2 and reduced TIMP-2 expression levels and a higher COL-I/III ratio. Young CVI patients with venous reflux suffer chronic DNA damage, with consequences at both the local tissue and systemic levels, possibly associated with ageing.This study (FIS-PI18/00912) was supported by the Instituto de Salud Carlos III (Plan Estatal de I + D+i 2013-2016) and co-financed by the European Development Regional Fund âA way to achieve Europeâ (ERDF) and B2017/BMD-3804 MITIC-CM
Selberg Supertrace Formula for Super Riemann Surfaces III: Bordered Super Riemann Surfaces
This paper is the third in a sequel to develop a super-analogue of the
classical Selberg trace formula, the Selberg supertrace formula. It deals with
bordered super Riemann surfaces. The theory of bordered super Riemann surfaces
is outlined, and the corresponding Selberg supertrace formula is developed. The
analytic properties of the Selberg super zeta-functions on bordered super
Riemann surfaces are discussed, and super-determinants of Dirac-Laplace
operators on bordered super Riemann surfaces are calculated in terms of Selberg
super zeta-functions.Comment: 43 pages, amste
Radiation Hydrodynamical Instabilities in Cosmological and Galactic Ionization Fronts
Ionization fronts, the sharp radiation fronts behind which H/He ionizing
photons from massive stars and galaxies propagate through space, were
ubiquitous in the universe from its earliest times. The cosmic dark ages ended
with the formation of the first primeval stars and galaxies a few hundred Myr
after the Big Bang. Numerical simulations suggest that stars in this era were
very massive, 25 - 500 solar masses, with H II regions of up to 30,000
light-years in diameter. We present three-dimensional radiation hydrodynamical
calculations that reveal that the I-fronts of the first stars and galaxies were
prone to violent instabilities, enhancing the escape of UV photons into the
early intergalactic medium (IGM) and forming clumpy media in which supernovae
later exploded. The enrichment of such clumps with metals by the first
supernovae may have led to the prompt formation of a second generation of
low-mass stars, profoundly transforming the nature of the first protogalaxies.
Cosmological radiation hydrodynamics is unique because ionizing photons coupled
strongly to both gas flows and primordial chemistry at early epochs,
introducing a hierarchy of disparate characteristic timescales whose relative
magnitudes can vary greatly throughout a given calculation. We describe the
adaptive multistep integration scheme we have developed for the self-consistent
transport of both cosmological and galactic ionization fronts.Comment: 6 pages, 4 figures, accepted for proceedings of HEDLA2010, Caltech,
March 15 - 18, 201
Aspects of String-Gas Cosmology at Finite Temperature
We study string-gas cosmology in dilaton gravity, inspired by the fact that
it naturally arises in a string theory context. Our main interest is the
thermodynamical treatment of the string-gas and the resulting implications for
the cosmology. Within an adiabatic approximation, thermodynamical equilibrium
and a small, toroidal universe as initial conditions, we numerically solve the
corresponding equations of motions in two different regimes describing the
string-gas thermodynamics: (i) the Hagedorn regime, with a single scale factor,
and (ii) an almost-radiation dominated regime, which includes the leading
corrections due to the lightest Kaluza Klein and winding modes, with two scale
factors. The scale factor in the Hagedorn regime exhibits very slow time
evolution with nearly constant energy and negligible pressure. By contrast, in
case (ii) we find interesting cosmological solutions where the large dimensions
continue to expand and the small ones are kept undetectably small.Comment: 21 pages, 5 eps figure
Dynamic Evolution Model of Isothermal Voids and Shocks
We explore self-similar hydrodynamic evolution of central voids embedded in
an isothermal gas of spherical symmetry under the self-gravity. More
specifically, we study voids expanding at constant radial speeds in an
isothermal gas and construct all types of possible void solutions without or
with shocks in surrounding envelopes. We examine properties of void boundaries
and outer envelopes. Voids without shocks are all bounded by overdense shells
and either inflows or outflows in the outer envelope may occur. These
solutions, referred to as type void solutions, are further
divided into subtypes and
according to their characteristic behaviours across the sonic critical line
(SCL). Void solutions with shocks in envelopes are referred to as type
voids and can have both dense and quasi-smooth edges.
Asymptotically, outflows, breezes, inflows, accretions and static outer
envelopes may all surround such type voids. Both cases of
constant and varying temperatures across isothermal shock fronts are analyzed;
they are referred to as types and
void shock solutions. We apply the `phase net matching procedure' to construct
various self-similar void solutions. We also present analysis on void
generation mechanisms and describe several astrophysical applications. By
including self-gravity, gas pressure and shocks, our isothermal self-similar
void (ISSV) model is adaptable to various astrophysical systems such as
planetary nebulae, hot bubbles and superbubbles in the interstellar medium as
well as supernova remnants.Comment: 24 pages, 13 figuers, accepted by ApS
Neutrino Masses in the Supersymmetric Standard Model with Right-Handed Neutrinos and Spontaneous R-Parity Violation
We propose an extension of the supersymmetric standard model with
right-handed neutrinos and a singlet Higgs field, and study the neutrino masses
in this model. The Majorana masses for the right-handed neutrinos are generated
around the supersymmetry breaking scale through the vacuum expectation value of
the singlet Higgs field. This model may induce spontaneous R-parity violation
via the vacuum expectation value of the right-handed sneutrino. In the case,
the effective theory is similar to a bilinear R-parity violating model. There
are two sources for the neutrino masses: one is this bilinear R-parity breaking
effect, and the other is the ordinary seesaw effect between left- and
right-handed neutrinos. Combining these two effects, the hierarchical neutrino
mass pattern arises even when the neutrino Yukawa matrices are not
hierarchical. We acquire appropriate masses and mixings to explain both the
solar and atmospheric neutrino oscillations.Comment: 22pages, RevTeX, 3 ps figures; a reference adde
Off-Diagonal Elements of the DeWitt Expansion from the Quantum Mechanical Path Integral
The DeWitt expansion of the matrix element M_{xy} = \left\langle x \right|
\exp -[\case{1}{2} (p-A)^2 + V]t \left| y \right\rangle, in
powers of can be made in a number of ways. For (the case of interest
when doing one-loop calculations) numerous approaches have been employed to
determine this expansion to very high order; when (relevant for
doing calculations beyond one-loop) there appear to be but two examples of
performing the DeWitt expansion. In this paper we compute the off-diagonal
elements of the DeWitt expansion coefficients using the Fock-Schwinger gauge.
Our technique is based on representing by a quantum mechanical path
integral. We also generalize our method to the case of curved space, allowing
us to determine the DeWitt expansion of \tilde M_{xy} = \langle x| \exp
\case{1}{2} [\case{1}{\sqrt {g}} (\partial_\mu - i
A_\mu)g^{\mu\nu}{\sqrt{g}}(\partial_\nu - i A_\nu) ] t| y \rangle by use of
normal coordinates. By comparison with results for the DeWitt expansion of this
matrix element obtained by the iterative solution of the diffusion equation,
the relative merit of different approaches to the representation of as a quantum mechanical path integral can be assessed. Furthermore, the
exact dependence of on some geometric scalars can be
determined. In two appendices, we discuss boundary effects in the
one-dimensional quantum mechanical path integral, and the curved space
generalization of the Fock-Schwinger gauge.Comment: 16pp, REVTeX. One additional appendix concerning end-point effects
for finite proper-time intervals; inclusion of these effects seem to make our
results consistent with those from explicit heat-kernel method
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