5,5-Dimethyl-2,2-bis­(pyridin-2-yl)-1,3-diazinane

In the mol­ecule of the title compound, C16H20N4, the 1,3-diazinane ring adopts a chair conformation and the dihedral angle formed by the pyridine rings is 78.64 (8)°. The mol­ecular conformation is stabilized by an intra­molecular C—H⋯N hydrogen bond, forming an S(6) ring motif. In the crystal, centrosymmetrically related mol­ecules are linked into dimers by pairs of N—H⋯N hydrogen bonds, generating rings of R 2 2(10) graph-set motif

Knowledge of Emergency Contraception Among Married Women Attending Antenatal Clinics, Makkah Saudi Arabia 2022

Background: Contraception is an effective mean of Family Planning (FP) and fertility control, promotes maternal and child health. It is interesting to explore the perception and use of contraceptives among Saudi women. The usage of contraceptive has  a significant part in reducing fertility and control of population, which in turn is important for the development of the nation. Despite the advancements in current methods of contraception, unintended pregnancies are still widespread in the Kingdom of Saudi Arabia which adversely impacts the well-being and health of women and their families. Unintended pregnancies pose a major challenge to the reproductive health of young adults in developing countries. students are an important high-risk group in any society and emergency contraceptives can prevent unintended pregnancies and its consequences in this high risk group, contraception is unique among medical interventions in the breadth of its positive outcomes. An effective means of Family Planning (FP) and fertility control promotes maternal and child health. Aim of the study: The study aimed to  assessment  the level of knowledge of emergency contraception among married women attending antenatal clinics, Makkah (2022). Methods: cross sectional descriptive study has be conducted using saudi women who fulfilling the inclusion criteria, used to randomly select women from Primary Health Care Centers (PHCCs) in Makkah in Saudi Arabia . using a well-structured pretested questionnaire composed of four main parts to collect the data. Our total participants were (200).Results: the majority of the participants answer the correct timing of emergency contraceptive pill (Within 5 days) were (86.0%)while IUD (Within 5 days) were (77.0%) while Total Knowledge regarding emergency contraceptive the majority of participants answer yes were (88.0%), regarding the ever using emergency contraception the majority of participants answer no were  (75.0%). Conclusion: In the light of the above results, there is an urgent need to improve the knowledge of Saudi women in age of fertility towards the use of modern contraceptives , low utilization was notices mainly due to religious concerns. Awareness programmers should be organized by the management on emergency contraception and other modern contraceptive methods

5,5-Dimethyl-2,2-di(pyridin-2-yl)hexahydropyrimidine

Novel 5,5-dimethyl-2,2-di(pyridin-2-yl)hexahydropyrimidine was synthesized in good yield by a one-pot condensation reaction of 2,2-dimethylpropane-1,3-diamine with di(pyridin-2-yl)methanoneusing dichloromethane as solvent at room temperature. The structure of the synthesized compound was assigned on the basis of its elemental analysis, UV-visible, 1H-NMR, 13C-NMR, IR, and mass spectral data

Gut Microbiota Dynamics in Relation to Long-COVID-19 Syndrome: Role of Probiotics to Combat Psychiatric Complications

Increasing numbers of patients who recover from COVID-19 report lasting symptoms, such as fatigue, muscle weakness, dementia, and insomnia, known collectively as post-acute COVID syndrome or long COVID. These lasting symptoms have been examined in different studies and found to influence multiple organs, sometimes resulting in life-threating conditions. In this review, these symptoms are discussed in connection to the COVID-19 and long-COVID-19 immune changes, highlighting oral and psychiatric health, as this work focuses on the gut microbiota’s link to long-COVID-19 manifestations in the liver, heart, kidney, brain, and spleen. A model of this is presented to show the biological and clinical implications of gut microbiota in SARS-CoV-2 infection and how they could possibly affect the therapeutic aspects of the disease. Probiotics can support the body’s systems in fighting viral infections. This review focuses on current knowledge about the use of probiotics as adjuvant therapies for COVID-19 patients that might help to prevent long-COVID-19 complications

The effectiveness of simulation-based training in general health practitioner education

The objective of this research was to examine the efficacy of simulation-based training in the field of nursing education. A thorough search of electronic databases was done to identify relevant research using a systematic literature review. The researchers used inclusion criteria to identify studies that specifically examined the effects of simulation-based training in nursing education on a range of outcomes. The review included both quantitative and qualitative investigations. Thematic analysis was conducted on the retrieved data in order to uncover prevalent patterns and topics pertaining to the efficacy of simulation-based training. The assessment of the listed studies' quality was conducted using suitable methodologies. The review's results underscored the advantages of incorporating simulation-based training into nursing school, including enhanced information acquisition, competence enhancement, and increase in self-assurance. Nevertheless, obstacles such as financial implications, personnel training, and student apprehension were also recognized. The research underscores the need for more investigation and agreement among nursing experts in order to develop a robust body of data about the efficacy of simulation-based training. The results of this research enhance comprehension of the influence of simulation-based training in the field of nursing education and provide suggestions for its integration and enhancement