Veterinarsko značenje komarčića roda Culicoides (Ceratopogonidae) u nekim podruèjima Saudijske Arabije.

Despite reports of severe outbreaks of arboviral diseases in domestic animals in Saudi Arabia, very little effort has been made to study the potential local vectors of these diseases. Diseases such as bluetongue and African horse sickness were reported in Saudi Arabia. Such diseases are internationally known to be vectored by Culicoides midges. The present study was undertaken at three localities in Saudi Arabia where arboviral activity had previously been reported. Results revealed the presence of four Culicoides species in the three localities. Two of these species were confirmed as vectors of arboviruses of domestic animals in neighbouring countries. The results were discussed in relation to the epidemiology of arboviral diseases in Saudi Arabia.Usprkos pojave teških arbovirusnih zaraza u domaćih životinja u Saudijskoj Arabiji, vrlo malo pozornosti posvećuje se istraživanjima mogućih vektora. U Saudijskoj Arabiji javljaju se bolesti kao što su bolest plavog jezika i konjska kuga. Poznato je da njih prenose komarčići roda Culicoides. Istraživanje je poduzeto na trima područjima u Saudijskoj Arabiji na kojima je već prethodno dokazana aktivnost arbovirusa. Dokazane su četiri vrste komarčića. Potvrđeno je da dvije od tih vrsta služe kao vektori arbovirusa u domaćih životinja. Rezultati su razmatrani u sklopu epizootiologije arbovirusnih bolesti u Saudijskoj Arabiji

Exploring Challenges to COVID-19 Vaccination in the Darfur Region of Sudan.

The current COVID-19 pandemic has affected the ability of health systems to provide essential services globally. The Darfur region, located in the western part of Sudan, has been largely devastated by the war that began in 2003 and has been drawing considerable attention from the international community. The war, which erupted as a result of environmental, political, and economic factors, has led to tragic outcomes. Collapsing health-care infrastructures, health workforce shortages, lack of storage facilities for medicines and medical products, and inadequate access to health services are some of the effects of the war. After Sudan received the AstraZeneca COVID-19 vaccine through the COVID-19 Vaccines Global Access facility, significant challenges have been implicated in the delivery, storage, and use of the vaccine in the Darfur region. Lack of vaccine storage and transportation facilities, vaccination hesitancy, inequity in the distribution to health facilities, and shortage of health-care professionals resulting from insecurity and instability have added an extra layer of burden on local authorities and their ability to manage COVID-19 vaccinations in the region adequately. Addressing the impact of COVID-19 requires an effectively managed vaccination program. In the face of current challenges in Darfur, ensuring a fully vaccinated population might remain far-fetched and improbable if meaningful efforts are not put in place by all stakeholders and actors to address some of the challenges identified

Veterinarsko značenje komarčića roda Culicoides (Ceratopogonidae) u nekim podruèjima Saudijske Arabije.

Despite reports of severe outbreaks of arboviral diseases in domestic animals in Saudi Arabia, very little effort has been made to study the potential local vectors of these diseases. Diseases such as bluetongue and African horse sickness were reported in Saudi Arabia. Such diseases are internationally known to be vectored by Culicoides midges. The present study was undertaken at three localities in Saudi Arabia where arboviral activity had previously been reported. Results revealed the presence of four Culicoides species in the three localities. Two of these species were confirmed as vectors of arboviruses of domestic animals in neighbouring countries. The results were discussed in relation to the epidemiology of arboviral diseases in Saudi Arabia.Usprkos pojave teških arbovirusnih zaraza u domaćih životinja u Saudijskoj Arabiji, vrlo malo pozornosti posvećuje se istraživanjima mogućih vektora. U Saudijskoj Arabiji javljaju se bolesti kao što su bolest plavog jezika i konjska kuga. Poznato je da njih prenose komarčići roda Culicoides. Istraživanje je poduzeto na trima područjima u Saudijskoj Arabiji na kojima je već prethodno dokazana aktivnost arbovirusa. Dokazane su četiri vrste komarčića. Potvrđeno je da dvije od tih vrsta služe kao vektori arbovirusa u domaćih životinja. Rezultati su razmatrani u sklopu epizootiologije arbovirusnih bolesti u Saudijskoj Arabiji

Prevalence of Malaria Parasite among Pregnant Women Attending to Saudi Kassala Teaching Hospital in Kassala State, Eastern Sudan

Objective. Malaria during pregnancy is a priority area for malaria research and control as pregnant women represent a high risk group for severe malaria, and the presentation of malaria during pregnancy varies according to the level of transmission in the area; so the aim of this study is to determine the prevalence rates of malaria parasite among pregnant women attending to Saudi Kassala Teaching hospital in Kassala state, 2022. Methods. A cross-sectional study was carried out in Saudi Kassala Teaching hospital in Kassala State. This study involved one hundred and eighty-five blood samples collected from pregnant women who was then examined by using blood films and ICT for malaria, and the data were collected by a structured questionnaire and analyzed using SPSS version 21. Results. The prevalence of malaria among pregnant women was 2.2% (95% CI: 0.006–0.054). There was no significant difference among the different age groups with respect to the prevalence of malaria (P value = 0.483). The prevalence of malaria in rural residency was 2.2%, and this was significantly more common than the urban residency (P value = 0.021). When compared across the gestational trimesters, there was no significant difference between them (P value = 0.518). The number of gravidity is not related to malaria infection (P value = 0.737). The presence of symptom compliant of malaria during pregnancy does not suggest the presence of malaria (P value = 0.152). No difference was found between the different educational levels with respect to the prevalence of malaria (P value = 0.362). The result showed that there was 1 (0.5%) negative result in ICT which was positive in blood film for malaria (BFFM) and there were 3 (1.6%) positive malaria parasites by both methods in all 185 samples with statistically insignificant differences (P = 0.703). Conclusion. Plasmodium falciparum was only species detected in this study. Malaria among pregnant women was more prevalent in rural areas. However, other factors such as age, gestational age, gravidity, and educational level do not affect the prevalence of malaria in pregnant women. The presence of symptomatic compliant of malaria during pregnancy does not suggest the presence of malaria. The use of ICT or BFFM has similar diagnostic outcome for malaria in pregnancy

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

Background: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods: The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18-49, 50-69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results: NNVs were more favourable in surgical patients than the general population. The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351; best case 196, worst case 816) or non-cancer surgery (733; best case 407, worst case 1664). Both exceeded the NNV in the general population (1840; best case 1196, worst case 3066). NNVs for surgical patients remained favourable at a range of SARS-CoV-2 incidence rates in sensitivity analysis modelling. Globally, prioritizing preoperative vaccination of patients needing elective surgery ahead of the general population could prevent an additional 58 687 (best case 115 007, worst case 20 177) COVID-19-related deaths in 1 year. Conclusion: As global roll out of SARS-CoV-2 vaccination proceeds, patients needing elective surgery should be prioritized ahead of the general population