Invisible Market: Energy and Agricultural Technologies for Women's Economic Advancement

This research explores what it takes for technology initiatives, specifically in the energy and agricultural sectors, to reach and economically benefit women in developing countries through market-based strategies that have the potential for achieving scale and financial sustainability. It builds on ICRW's landmark paper, Bridging the Gender Divide: How Technology Can Advance Women Economically, which made the case for how technologies can create pathways for strengthening women's economic opportunities. Through a field-level investigation and interviews with experts, the authors examine how women's use of technology and their involvement in the development and distribution of a technology can not only advance women economically, but also can benefit enterprise-based technology initiatives by expanding their markets and helping them generate greater financial returns

Most \u3cem\u3eCaenorhabditis elegans\u3c/em\u3e MicroRNAs are Individually Not Essential for Development or Viability

MicroRNAs (miRNAs), a large class of short noncoding RNAs found in many plants and animals, often act to post-transcriptionally inhibit gene expression. We report the generation of deletion mutations in 87 miRNA genes in Caenorhabditis elegans, expanding the number of mutated miRNA genes to 95, or 83% of known C. elegans miRNAs. We find that the majority of miRNAs are not essential for the viability or development of C. elegans, and mutations in most miRNA genes do not result in grossly abnormal phenotypes. These observations are consistent with the hypothesis that there is significant functional redundancy among miRNAs or among gene pathways regulated by miRNAs. This study represents the first comprehensive genetic analysis of miRNA function in any organism and provides a unique, permanent resource for the systematic study of miRNAs

The Singapore summit: integrating the 10 essential shared capabilities into an international research and clinical framework for mental health - the international standing conference for capability development for mental health

The Singapore summit: integrating the 10 essential shared capabilities into an international research and clinical framework for mental health - the international standing conference for capability development for mental health

Most Caenorhabditis elegans microRNAs are individually not essential for development or viability.

MicroRNAs (miRNAs), a large class of short noncoding RNAs found in many plants and animals, often act to post-transcriptionally inhibit gene expression. We report the generation of deletion mutations in 87 miRNA genes in Caenorhabditis elegans, expanding the number of mutated miRNA genes to 95, or 83% of known C. elegans miRNAs. We find that the majority of miRNAs are not essential for the viability or development of C. elegans, and mutations in most miRNA genes do not result in grossly abnormal phenotypes. These observations are consistent with the hypothesis that there is significant functional redundancy among miRNAs or among gene pathways regulated by miRNAs. This study represents the first comprehensive genetic analysis of miRNA function in any organism and provides a unique, permanent resource for the systematic study of miRNAs