477 research outputs found

    Caveat Excavator: A Sea Bird Midden on Steep Head Island, North West Tasmania

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    Considerations for non man made artefacts; for example, shell middens created by sea birds, charcoal layers due to burnt ant hills, and flaked stones resulting from birds dropping pebbles

    A stratified archaeological site on great Glennie Island, Bass Strait

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    The minimum distance to Wilson's Promontory is 7km, but this is to the 40m perpendicular cliffs of Oberon Point. The only feasible landing or embarking places on the west coast of the Promontory opposite the island group are the beaches of Oberon Bay, Norman Bay at Tidal River or Squeaky Beach to the north. In all cases, the minimum open sea distance to the anchorage on the island is 9km. In western and southern Tasmania there was an inverse relationship between the intensity of use of an offshore island and the minimum cross-sea distance required to reach it

    A radiocarbon date for the final prehistoric occupation of Glennie Island Cave, Bass Strait

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    The previous issue of Australian Archaeology (no.9), described the discovery of a small cave on Great Glennie Island some 7km west of Wilson's Promontory, Bass Strait, Victoria (Jones and Allen 1979). A shell midden in this granite cave consisted mostly of limpets (Cellana solida) and in order to obtain a date for final occupation of the site, a sample of limpet shell was submitted to the ANU Radiocarbon Research Laboratory, hoping that it would at least indicate a date beyond that of the arrival of European sailors into Bass Strait at the very end of the 18th century and thus prove that the midden was genuinely of Aboriginal origin. This paper discusses the results of sample no. GIC/1968:ANU-2296 1440±100BP (Libby half life of 5568 years) on limpet shell 'Cellana solida'

    Equivalent biaxial strain evaluation in small punch testing using acoustic emission

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    The small punch test initially used mainly in the nuclear sector proved to be an efficient method of estimating the mechanical properties of materials, including fracture toughness. In general, the fracture toughness is estimated based on a correlation with equivalent biaxial fracture strain. However, the latter depends on knowing the onset of the unstable fracture. In this article, the acoustic emission technique is used within the small punch test for estimating the unstable fracture initiation and determining the corresponding punch displacement from the load–displacement curve. Although, the acoustic emission signal can be slightly altered due to the location of the sensor, the results confirm the potential of the acoustic emission technique for detecting the onset of the unstable cracking and thus accurately estimating the equivalent biaxial fracture strain. The accumulated energy during the small punch test is one of the relevant acoustic emission parameters in estimating the fracture onset since it can be associated with the accumulated strain energy released by the deformed material

    Exploring patient views and acceptance of multiparametric magnetic resonance imaging for the investigation of suspected prostate cancer (the PACT Study): a mixed-methods study protocol

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    BACKGROUND: The introduction of multiparametric magnetic resonance imaging (mpMRI) has improved the diagnosis of suspected prostate cancer, accurately risk-stratifying men before a biopsy. However, pre-biopsy mpMRI represents a significant deviation from the traditional approach of prostate specific antigen testing with subsequent systematic transrectal ultrasound-guided prostate biopsy and we have not yet explored the views of men who experience this new pathway. The purpose of the PACT study (PAtient views and aCceptance of mulTiparametric MRI) is to explore men’s perceptions of mpMRI. METHODS: PACT will be conducted at teaching hospitals in which mpMRI is central to the prostate cancer diagnostic pathway using a two-phase, mixed-methods, quantitative and qualitative approach. In phase I, men referred with suspected prostate cancer will complete detailed surveys to explore their views on the mpMRI-directed pathway compared to the traditional pathway and on what constitutes ‘significant’ prostate cancer. In phase II, these themes will be expanded upon with in-depth, semi-structured interviews. Qualitative data will be transcribed and thematically analysed, and quantitative questionnaire responses will be analysed statistically. DISCUSSION: PACT will provide the first detailed insight into patient perceptions on the use and acceptability of mpMRI. Furthermore, results from PACT will help contribute to the resolution of outstanding controversies that surround this technology

    2021 assessment of the status of the West Coast Demersal Scalefish Resource

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    A recovery program for the West Coast Demersal Scalefish Resource was introduced between late 2007 and early 2010, based on the maintenance of retained catches of demersal species (overall suite and each indicator species) by both the commercial and recreational sectors below 50% of the catches reported in 2005/06 (original catch recovery benchmarks)

    Genetic landscape of prostate cancer conspicuity on multiparametric MRI: a protocol for a systematic review and bioinformatic analysis

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    Download PDFPDF Urology Protocol Genetic landscape of prostate cancer conspicuity on multiparametric MRI: a protocol for a systematic review and bioinformatic analysis Joseph M Norris1, Benjamin S Simpson1, Marina A Parry2, Clare Allen3, Rhys Ball4, Alex Freeman4, Daniel Kelly5, Alex Kirkham3, Veeru Kasivisvanathan1, Hayley C Whitaker1, Mark Emberton1 Author affiliations Abstract Introduction The introduction of multiparametric MRI (mpMRI) has enabled enhanced risk stratification for men at risk of prostate cancer, through accurate prebiopsy identification of clinically significant disease. However, approximately 10%–20% of significant prostate cancer may be missed on mpMRI. It appears that the genomic basis of lesion visibility or invisibility on mpMRI may have key implications for prognosis and treatment. Here, we describe a protocol for the first systematic review and novel bioinformatic analysis of the genomic basis of prostate cancer conspicuity on mpMRI. Methods and analysis A systematic search of MEDLINE, PubMed, EMBASE and Cochrane databases will be conducted. Screening, data extraction, statistical analysis and reporting will be performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Included papers will be full text articles, written between January 1980 and December 2019, comparing molecular characteristics of mpMRI-visible lesions and mpMRI-invisible lesions at the DNA, DNA-methylation, RNA or protein level. Study bias and quality will be assessed using a modified Newcastle-Ottawa score. Additionally, we will conduct a novel bioinformatic analysis of supplementary material and publicly available data, to combine transcriptomic data and reveal common pathways highlighted across studies. To ensure methodological rigour, this protocol is written in accordance with the PRISMA Protocol 2015 checklist. Ethics and dissemination Ethical approval will not be required, as this is an academic review of published literature. Findings will be disseminated through publications in peer-reviewed journals, and presentations at national and international conferences

    The EUCAMS gear partnership - a model of industry/academic collaboration

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    Challenges in maintenance systems can pose multi-faceted problems, which are difficult to resolve alone. Over a four year period, a partnership evolved a vision for tackling the understanding of fundamentally difficult mechanical failures and their detection, with potential for practical exploitation of the solutions. The partnership assembled a team of researchers and far-sighted project management, to undertake a study of gearbox failures, including finite element modelling, gear testing, and signal analysis. The partnership trained a series of doctoral and postdoctoral staff in running an integrated project, coping with changes in staffing and locations. The final stages of the work will validate the models and signal processing
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