Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Turnstile Justice: Issues in American Corrections (2nd Edition)

Focused on the major issues facing corrections today, this collection of readings analyzes the social context within which current American punishment philosophy and practice take place. Each chapter deals with a major topic, policy, or strategy that is currently generating debate in the correctional field, and varying points of view reflect the diversity of thought on each critical issue. The author of each chapter provides factual information and data on an issue or topic and then invites readers to step back and critically examine the impact of the correctional problem on the system or society. American Corrections in the New Millennium. Societal Change and Its Impact on Corrections. Correctional Philosophies. Prison Violence. The Inmate Subculture in Juvenile Correctional Settings. Health Care for Women Offenders. Jailed Fathers. Correctional Boot Camps. Detention in I.N.S. Jails. Postsecondary Correctional Education. For anyone involved in criminal justice/corrections.https://digitalcommons.unomaha.edu/criminaljusticefacbooks/1019/thumbnail.jp