11 research outputs found

    Age-Defying and Photoprotective Potential of Geranium/Calendula Essential Oil Encapsulated Vesicular Cream on Biochemical Parameters against UVB Radiation Induced Skin Aging in Rat

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    UVB irradiation promotes the production of reactive oxygen species, which can lead to an increase in oxidative stress in the cell and the generation of toxic components, resulting in photoaging. Essential oils (EOs) are well-known in the cosmetics sector for their beneficial effects, as they have a wide range of biological activities. Considering this fact, the current study investigates the photoprotective potential of geranium essential oil (GEO)/calendula essential oil (CEO) encapsulated vesicular cream on the biochemical parameters of the skin of albino rats exposed to UVB radiation. After 30 days of treatment with cream formulations and UVB irradiation, the skin tissue was assayed for several biochemical parameters and histopathology analysis. The results of biochemical study revealed that, in comparison to non-vesicular creams, vesicular cream formulations were able to protect the endogenous skin natural antioxidant system by maintaining superoxide dismutase, catalase, total protein, ascorbic acid, and hydroxyproline levels and by decreasing malondialdehyde levels in the skin after UVB exposure. Changes in various cellular structures along with the change in the epidermis and dermis of the skin after UVB exposure in the treated group were observed by a histopathology of skin tissue and compared to the non-treated group, which revealed the skin damaging effect of UVB radiation and the protective effect of vesicular creams. The results suggest that the GEO/CEO-encapsulated vesicular creams have the potential to protect the skin against harmful UVB radiation by maintaining the natural antioxidant defence mechanism of the skin. In conclusion, this research presents novel herbal cosmetic formulations with improved antioxidant capacity and photoprotective potential that may help to slow down the skin aging process

    Age-Defying and Photoprotective Potential of Geranium/Calendula Essential Oil Encapsulated Vesicular Cream on Biochemical Parameters against UVB Radiation Induced Skin Aging in Rat

    No full text
    UVB irradiation promotes the production of reactive oxygen species, which can lead to an increase in oxidative stress in the cell and the generation of toxic components, resulting in photoaging. Essential oils (EOs) are well-known in the cosmetics sector for their beneficial effects, as they have a wide range of biological activities. Considering this fact, the current study investigates the photoprotective potential of geranium essential oil (GEO)/calendula essential oil (CEO) encapsulated vesicular cream on the biochemical parameters of the skin of albino rats exposed to UVB radiation. After 30 days of treatment with cream formulations and UVB irradiation, the skin tissue was assayed for several biochemical parameters and histopathology analysis. The results of biochemical study revealed that, in comparison to non-vesicular creams, vesicular cream formulations were able to protect the endogenous skin natural antioxidant system by maintaining superoxide dismutase, catalase, total protein, ascorbic acid, and hydroxyproline levels and by decreasing malondialdehyde levels in the skin after UVB exposure. Changes in various cellular structures along with the change in the epidermis and dermis of the skin after UVB exposure in the treated group were observed by a histopathology of skin tissue and compared to the non-treated group, which revealed the skin damaging effect of UVB radiation and the protective effect of vesicular creams. The results suggest that the GEO/CEO-encapsulated vesicular creams have the potential to protect the skin against harmful UVB radiation by maintaining the natural antioxidant defence mechanism of the skin. In conclusion, this research presents novel herbal cosmetic formulations with improved antioxidant capacity and photoprotective potential that may help to slow down the skin aging process

    Active Ingredients and Carriers in Nutritional Eco-Cosmetics

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    Beauty and personal care became a significant part of the global economy for two reasons: (1) The elderly growing in the global population and (2) the desire of women and men to appear younger and more attractive. Thus, both young and old people are looking for revolutionary nutritional eco-cosmetics (combined use of cosmeceuticals and nutraceuticals) manufactured by natural active ingredients, using biopolymers as substrates, and made by innovative and sustainable technologies. Consequently, the market of both cosmetics and diet supplements is continually growing together with the request of natural active ingredients, including bio-peptides and biological macromolecules such as chitin and lignin. Therefore, both consumers and industry need to recover innovative active ingredients and carriers (vehicles), naturally derived and supported by advanced methods for controlling their effectiveness and safeness on skin and mucous membrane layers. The use of selected bio-ingredients, such as hyaluronic acid and bio-mimetic peptides, obtained by advanced, innovative and sustainable bio nanotechnologies, will be of interest to develop smart cosmeceutical and nutraceutical formulations. Innovation is considered the key business strategy to drive sustainable economic growth. For trying to reduce waste and produce sustainable, biodegradable and innovative products, the realization of new non-woven tissues, used as carriers for making innovative cosmeceuticals and nutraceuticals was considered. Both carriers and active ingredients have been obtained from food waste to reduce loss and pollution. This review will report a brief description of the skin functions, trying also to focus and discuss some of the active ingredients and carriers used in nutritional eco-cosmetics to clarify the supposed mechanism of action, effectiveness and safeness of both active ingredients and carriers, as well as the supposed activity of beauty and personal care products

    From Cosmetics to Innovative Cosmeceuticals—Non-Woven Tissues as New Biodegradable Carriers

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    Due to pollution and climate-change fear, further increased by the COVID19 pandemic, consumers are looking for body and mind health by the request of more effective and safe products, including the anti-aging skincare cosmeceuticals.. The term “cosmeceuticals” was coined in 1962 as a fusion of cosmetic and pharmaceutical to cover a new class of products able to achieve aesthetic and drug-like benefits. They not only improve the skin’s appearance, but also treat different dermatological conditions, through a physiological activity, shown by in vitro and in vivo studies. This new category of cosmetics should contain no recognized drugs, but nonetheless have medicinal value. Consumers, in fact, are looking for products able to regenerate the skin and maintain not only a youthful appearance together with well-ness and well-being, but preserving the environment also. Consequently, they are searching for cosmetics and food made with high-quality natural ingredients, packaged with biodegradable materials and realized by sustainable technologies, possibly at zero waste. Consumers, in fact, are afraid of the pollution and plastics invading lands and oceans, causing many frequent disasters on our planet. New and smart tissues and films, made by polysaccharides and natural active ingredients, are proposed as innovative cosmeceuticals. These non-woven tissues, embedded by micro/nano complexes of chitin and lignin encapsulating different active ingredients, could represent a new category of vehicles that are characterized for their high effectiveness and safeness. Moreover, they do not induce allergic nor sensitizing phenomena, being biodegradable; skin- and environmentally friendly; and free of preservatives, emulsifiers, colors, fragrances and any kind of chemicals. Last but not least, polysaccharides, chitin and lignin may be obtained from industrial and agro-forestry waste, safeguarding the natural raw materials for the future generations

    Nanotechnology-Based Cosmeceuticals

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    Active Ingredients and Carriers in Nutritional Eco-Cosmetics

    No full text
    Beauty and personal care became a significant part of the global economy for two reasons: (1) The elderly growing in the global population and (2) the desire of women and men to appear younger and more attractive. Thus, both young and old people are looking for revolutionary nutritional eco-cosmetics (combined use of cosmeceuticals and nutraceuticals) manufactured by natural active ingredients, using biopolymers as substrates, and made by innovative and sustainable technologies. Consequently, the market of both cosmetics and diet supplements is continually growing together with the request of natural active ingredients, including bio-peptides and biological macromolecules such as chitin and lignin. Therefore, both consumers and industry need to recover innovative active ingredients and carriers (vehicles), naturally derived and supported by advanced methods for controlling their effectiveness and safeness on skin and mucous membrane layers. The use of selected bio-ingredients, such as hyaluronic acid and bio-mimetic peptides, obtained by advanced, innovative and sustainable bio nanotechnologies, will be of interest to develop smart cosmeceutical and nutraceutical formulations. Innovation is considered the key business strategy to drive sustainable economic growth. For trying to reduce waste and produce sustainable, biodegradable and innovative products, the realization of new non-woven tissues, used as carriers for making innovative cosmeceuticals and nutraceuticals was considered. Both carriers and active ingredients have been obtained from food waste to reduce loss and pollution. This review will report a brief description of the skin functions, trying also to focus and discuss some of the active ingredients and carriers used in nutritional eco-cosmetics to clarify the supposed mechanism of action, effectiveness and safeness of both active ingredients and carriers, as well as the supposed activity of beauty and personal care products

    Food Loss and Food Waste for Green Cosmetics and Medical Devices for a Cleaner Planet

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    To stay wealthy in a world where all can live in prosperity and wellbeing, it is necessary to develop sustainable growth at net zero emissions to stop climate change, neutralizing both risks and diseases such as the COVID-19 pandemic and inequalities. Changing the worldwide use of the great quantity of food loss and waste can help to move in this direction. At this purpose, it seems useful to transform food waste into richness, extracting and using its content in natural ingredients and biopolymers to make new sustainable products and goods, including cosmetics and medical devices. Many of these ingredients are not only bioactive molecules considered of interest to produce these consumer products but are also useful in reducing the environmental footprint. The active agents may be obtained, for example, from waste material such as grapes or olive pomace, which include, among others natural polymers, phythosterols, vitamins, minerals and unsaturated fatty acids. Among the polymers, chitin and lignin have shown particular interest because biodegradable, nontoxic, skin- and environmentally friendly ingredients can be obtained at low cost from food and forestry waste, respectively. According to our experience, these polymers may be used to make nanocomposites and micro-nanoparticles that encapsulate different active ingredients, and which may be embedded into gel and non-woven tissues to realize advanced medications and smart cosmeceuticals. However, to utilize food waste in the best possible way, a better education of both industry and the consumer is considered necessary, introducing all to change the ways of production and living. The consumer has to understand the need to privilege, food, cosmetics and goods by selecting products known to be effective that also have a low release of carbon dioxide. Thus, they must pay heed to purchasing cosmetics and medical devices made by natural ingredients and packaged by biodegradable and/or reusable containers that are possibly plastic free. Conversely, the industry must try to use natural raw materials obtained from waste by changing their actual production methods. Therefore, both industry and the consumer should depart from the linear economy, which is based on taking, making, and producing waste, to move into a circular economy, which is based on redesigning, reducing, reusing and recycling. Some examples will report on the possibility to use natural polymers, including chitin and lignin, to produce new cosmeceutical tissues. These innovative tissues, to be used as biodegradable carriers for making smart cosmetics and medical devices, may be produced at zero waste to save our health and the planet biodiversity
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