Additional file 3: Table S2. of Abdominal fat depots associated with insulin resistance and metabolic syndrome risk factors in black African young adults

Pearson’s correlation coefficients (P-values) between body fat parameters and individual metabolic traits in women. (XLS 11 kb

Additional file 1: Figure S1. of Abdominal fat depots associated with insulin resistance and metabolic syndrome risk factors in black African young adults

MRI image taken at the L4 vertebral body, showing visceral adipose tissue (VAT) in green, superficial subcutaneous adipose tissue (S-SCAT) in blue, and deep subcutaneous adipose tissue. (D_SCAT) in pink. (TIFF 429 kb

Accelerometry and ³¹P-MRS measurements for the participants with Down’s syndrome (DS) and those with a non Down’s syndrome related intellectual disability (ID).

<p>Data presented are mean (SEM).</p><p>k, PCr recovery rate constant; [Pi], concentration of inorganic phosphate; [PCr], concentration of phosphocreatine; [PDE], concentration of phosphodiester; [ADP], concentration of adenosine diphosphate; pH_i, intracellular pH.</p

Characteristics of the participants with Down’s syndrome (DS) and those with a non Down’s syndrome related intellectual disability (ID).

<p>Data presented are mean (SEM).</p><p>M, Male; F, Female; BMI, body mass index.</p

³¹P-MRS measures of mitochondrial function.

<p>(A) Representative single spectra (NA = 1) at rest (upper) and near end exercise (lower), with 2 Hz line broadening applied for illustrative purposes. (B) Corresponding PCr timecourse to the spectra in A, which illustrates the typical [PCr] end-exercise depletion in this study. The SNR of this timecourse was 46, significantly below average. The black line represents the monoexponential fit to both PCr recoveries. The recovery time constant, k, was 1.87 min⁻¹ and 1.83 min⁻¹ for recovery from exercise bouts 1 and 2 respectively. (C) Mean fractional PCr recovery curves for physical activity matched ID (grey squares; n = 11) and DS (black circles; n = 10). Five spectra were averaged to give a time resolution of 10 seconds for clarity in this figure. The monoexponential fit using the mean recovery rate constant is shown for ID (grey line) and DS (black line). (D) Recovery rate constant (k) for matched physical activity groups of ID (white bars; n = 11) and for DS (black bars; n = 10). In C–D, data are mean +/− SEM.</p