Funnel plot of studies testing for anti-EA IgG sero-positivity.

<p>Funnel plot of studies testing for anti-EA IgG sero-positivity.</p

Funnel plot for studies testing for anti-EBNA IgG sero-positivity.

<p>Funnel plot for studies testing for anti-EBNA IgG sero-positivity.</p

Combined OR in paediatric vs. adult studies.

<p>Note: P value is significant at or below 0.01.</p

Combined OR in studies using McDonlad/Poser criteria vs. other/criteria not specified.

<p>Note: P value is significant at or below 0.01.</p

Combined OR in studies with quality assessment score of 6 (median) or above vs. below 6.

<p>Note: <i>post hoc</i> analyses. P value is significant at or below 0.01.</p

Forest plot of the Odds ratio for anti-EBV IgG sero-negativity.

<p>Forest plot of the Odds ratio for anti-EBV IgG sero-negativity.</p

Additional file 1: Table S1. of Systematic review and meta-analysis of the sero-epidemiological association between Epstein-Barr virus and rheumatoid arthritis

Search strategy for systematic review; Figure S1. Forest plot anti-VCA IgG including excluded article by Saal et al. [25]; Figure S2. Forest plot anti-VCA IgG for age- and sex-matched studies; Figure S3. Forest plot anti-VCA IgG for community-controlled studies; study protocol; data extraction form; adapted Newcastle-Ottawa quality assessment scale. (PDF 440 kb

Forest plot of the Odds Ratio for anti-EA IgG sero-positivity.

<p>Note: the study Wagner, et al., (2000)<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0061110#pone.0061110-Wagner1" target="_blank">[56]</a> in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0061110#pone-0061110-g006" target="_blank">Figure 6</a> is an older version of the study Wandinger, et al., (2000)<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0061110#pone.0061110-Wandinger1" target="_blank">[53]</a>.</p

Combined OR in studies with confirmed MS cases vs. Confirmed and probable cases.

<p>Note: <i>post hoc</i> analyses. P value is significant at or below 0.01.</p

Combined OR in studies below median latitude vs. above the median.

<p>Note: P value is significant at or below 0.01.</p