Оцінка якості життя хворих на хронічне обструктивне захворювання легень за супутніх розладів психоемоційної сфери

Aim – to study quality of life (QOL) indicators in patients with chronic obstructive pulmonary disease (COPD) at different types and expressiveness of concomitant psycho-emotional disorders.Materials and methods. There were examined 206 patients with COPD (158 (76,7 %) men and 48 (23,3 %) women, whose mean age was 64,4±0,8 years, mean disease duration – 8,8±0,4 years) using clinical-functional and questionnaire methods of research. The psychic status of respondents was determined using the complex of standardized questionnaire methods. QOL was assessed using the Ukrainian version of the international questionnaire on QOL MOS SF-36. The statistical processing of data was realized using the package of statistical programs SPSS 20.0 for Windows by parametric and non-parametric methods according to the type of variables distribution.Results. It was established, that patients with COPD had statistically reliably higher mean values than practically healthy persons by scales of neurotization ((44,97±1,27) %, р=0,005), state anxiety ((42,82±0,64) points, р<0,001), trait anxiety ((44,95±0,63) points, р <0,001) and depressive states ((41,00±0,65) points, р<0,001). There were established the prevalence of psycho-emotional disorders in patients with COPD: neurotization (26,2 %), state anxiety (37,9 %), traitanxiety (49,5 %), depressive states (16,5 %).It was revealed that patients with COPD have reliably lower mean values than practically healthy persons by all indicators of physical, psychic and general statuses of QOL and change health comparing with the previous year.It was established, that each separate psycho-emotional disorder essentially influences QOL indicators of patients with COPD that is manifested in the reliable decrease of mean values by all scales of MOS SF-36 form.Conclusions. In the result of the study there were assessed QOL indicators of patients with COPD and also established their dependence on the type and expressiveness of concomitant psycho-emotional disordersУ хворих на хронічне обструктивне захворювання легень одними з найбільш частих коморбідних станів є розлади психоемоційної сфери. Досліджено показники якості життя хворих в залежності від виду та виразності психоемоційних розладів. Встановлено, що клінічно значимі синдроми невротизації, тривожності та депресивні стани посилюють негативний вплив захворювання на показники якості життя пацієнті

The birth of a healthy child in a married couple with a history of multiple unsuccessful attempts at ART by selecting sperm on oocyte-cumulus complexes. Case report

In male infertility, couples must use assisted reproductive technologies with the intracytoplasmic sperm injection (ICSI) technique. A significant disadvantage of ICSI is bypassing natural selection barriers since selective processes in the female reproductive tract are replaced by the choice of an embryologist based on sperm motility and morphological criteria. Various selection methods are being actively studied, bringing fertilization by ICSI closer to physiological, ensuring the selection of sperm with high DNA quality and good potential for fertilization. The article presents a clinical case of the birth of a healthy child in a married couple with severe male infertility and many ineffective attempts at assisted reproductive technologies using the method of sperm selection on oocyte-cumulus complexes. The child is physically healthy and develops according to age