HEMI-SYNC® AND RADIATION ONCOLOGY: A PILOT STUDY

This pilot study is reprinted from the Monroe Institute Hemi-Sync Journal, Vol. XXVI, Nos. 3 & 4, Summer/Fall 2008 Hemi-Sync, a binaural-beat brain-wave entrainment technology and consciousness-modulating tool developed by Robert Monroe and his associates, can be combined with guided meditation to produce a useful tool for behavioral medicine: the field of treating medical problems with behavioral modalities.The authors applied the technology to the problem of side effects of radiation treatment in cancer patients. Patients filled out the Brief Fatigue Inventory (BFI) daily in the course of listening to MIND FOOD Energy Walk. At the end of the study, participants also completed a patient satisfaction questionnaire, which included questions about pain. Only two of the sixteen patients who returned the BFI questionnaire found the tape ineffective for pain and fatigue.The data strongly support the binaural-beat exercise's effectiveness for relieving fatigue associated with radiation treatments. Though this was an open rather than a placebo-controlled study, the effect size is far beyond what one would expect from a placebo effect. This pilot study gives strong encouragement for using the Hemi-Sync technology as an adjunct to radiation oncology. Further investigation with a larger patient population is recommended

HEMI-SYNC® AND RADIATION ONCOLOGY: A PILOT STUDY

This pilot study is reprinted from the Monroe Institute Hemi-Sync Journal, Vol. XXVI, Nos. 3 & 4, Summer/Fall 2008 Hemi-Sync, a binaural-beat brain-wave entrainment technology and consciousness-modulating tool developed by Robert Monroe and his associates, can be combined with guided meditation to produce a useful tool for behavioral medicine: the field of treating medical problems with behavioral modalities.The authors applied the technology to the problem of side effects of radiation treatment in cancer patients. Patients filled out the Brief Fatigue Inventory (BFI) daily in the course of listening to MIND FOOD Energy Walk. At the end of the study, participants also completed a patient satisfaction questionnaire, which included questions about pain. Only two of the sixteen patients who returned the BFI questionnaire found the tape ineffective for pain and fatigue.The data strongly support the binaural-beat exercise's effectiveness for relieving fatigue associated with radiation treatments. Though this was an open rather than a placebo-controlled study, the effect size is far beyond what one would expect from a placebo effect. This pilot study gives strong encouragement for using the Hemi-Sync technology as an adjunct to radiation oncology. Further investigation with a larger patient population is recommended

Very Preterm Early Motor Repertoire and Neurodevelopmental Outcomes at 8 Years

BACKGROUND AND OBJECTIVES: Children born very preterm (<32 weeks' gestation) have more neurodevelopmental problems compared with term-born peers. Aberrant fidgety movements (FMs) are associated with adverse motor outcomes in children born very preterm. However, associations of aberrant FMs combined with additional movements and postures to give a motor optimality score-revised (MOS-R) with school-aged cognitive and motor outcomes are unclear. Our aim with this study was to determine those associations. METHODS: Of 118 infants born <30 weeks' gestation recruited into a randomized controlled trial of early intervention, 97 had a general movements assessment at 3 months' corrected age and were eligible for this study. Early motor repertoire including FMs and MOS-R were scored from videos of infant's spontaneous movement at 3 months' corrected age. At 8 years' corrected age, cognitive and motor performances were evaluated. Associations of early FMs and MOS-R with outcomes at 8 years were determined using linear regression. RESULTS: Seventy-eight (80%) infants with early motor repertoire data had neurodevelopmental assessments at 8 years. A higher MOS-R, and favorable components of the individual subscales of the MOS-R, including the presence of normal FMs, were associated with better performance for general cognition, attention, working memory, executive function and motor function at 8 years; eg, presence of normal FMs was associated with a 21.6 points higher general conceptual ability score (95% confidence interval: 12.8-30.5; P < .001) compared with absent FMs. CONCLUSIONS: Favorable early motor repertoire of infants born <30 weeks is strongly associated with improved cognitive and motor performance at 8 years

How well do RCMs and ESDs reproduce the occurrence of extreme precipitation events over Southeastern South America? A case study approach

Individual extreme precipitation eventsover Southeastern South America(SESA)during thes pringand summer time are responsible of more than 40% of the total accumulated seasonal precipitation. These extreme events are associated with the occurrence of organized convection in the region.Giventhe mesoscale features involved in their development..Fil: Solman, Silvina Alicia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones del Mar y la Atmósfera. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmósfera; ArgentinaFil: Bettolli, Maria Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones del Mar y la Atmósfera. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmósfera; ArgentinaFil: Doyle, Moira Evelina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones del Mar y la Atmósfera. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmósfera; ArgentinaFil: Blazquez, Josefina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones del Mar y la Atmósfera. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmósfera; ArgentinaFil: Feijoó, Martín. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones del Mar y la Atmósfera. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmósfera; ArgentinaFil: Olmo, Matías Ezequiel. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ciencias de la Atmósfera y los Océanos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Díaz, Gonzalo Martín. Ministerio de Defensa. Secretaria de Planeamiento. Servicio Meteorológico Nacional; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Balmaceda, Rocio. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ciencias de la Atmósfera y los Océanos; ArgentinaFil: Poggi, María Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ciencias de la Atmósfera y los Océanos; ArgentinaThe International Conference on Regional Climate CordexBeijingChinaWorld Climate Research Programm

The Grizzly, January 30, 1996

The Ruby is Dead • Research Conference Originates at Ursinus • The Soul of the Matter • Ursinus Recital Featured Two Organists • The Ursinus Blackout • Heefner Organ Recital Series Kicks Off • The Bear Facts About the Ursinus Mascot: Part 1 • Study Abroad: More Than Just an Academic Experience • Women\u27s Hoops Struggling • Bears In Thick of Playoff Race • Anecdotes of a Wagon Lost in Denver • Bears Nationally Ranked • Bears Look Tough to Beat as Centennial Tourney Hostshttps://digitalcommons.ursinus.edu/grizzlynews/1372/thumbnail.jp

Analysis of epigenetic changes in survivors of preterm birth reveals the effect of gestational age and evidence for a long term legacy

BACKGROUND: Preterm birth confers a high risk of adverse long term health outcomes for survivors, yet the underlying molecular mechanisms are unclear. We hypothesized that effects of preterm birth can be mediated through measurable epigenomic changes throughout development. We therefore used a longitudinal birth cohort to measure the epigenetic mark of DNA methylation at birth and 18 years comparing survivors of extremely preterm birth with infants born at term. METHODS: Using 12 extreme preterm birth cases and 12 matched, term controls, we extracted DNA from archived neonatal blood spots and blood collected in a similar way at 18 years of age. DNA methylation was measured at 347,789 autosomal locations throughout the genome using Infinium HM450 arrays. Representative methylation differences were confirmed by Sequenom MassArray EpiTYPER. RESULTS: At birth we found 1,555 sites with significant differences in methylation between term and preterm babies. At 18 years of age, these differences had largely resolved, suggesting that DNA methylation differences at birth are mainly driven by factors relating to gestational age, such as cell composition and/or maturity. Using matched longitudinal samples, we found evidence for an epigenetic legacy associated with preterm birth, identifying persistent methylation differences at ten genomic loci. Longitudinal comparisons of DNA methylation at birth and 18 years uncovered a significant overlap between sites that were differentially-methylated at birth and those that changed with age. However, we note that overlapping sites may either differ in the same (300/1,555) or opposite (431/1,555) direction during gestation and aging respectively. CONCLUSIONS: We present evidence for widespread methylation differences between extreme preterm and term infants at birth that are largely resolved by 18 years of age. These results are consistent with methylation changes associated with blood cell development, cellular composition, immune induction and age at these time points. Finally, we identified ten probes significantly associated with preterm individuals and with greater than 5% methylation discordance at birth and 18 years that may reflect a long term epigenetic legacy of preterm birth

The Grizzly, October 24, 1995

The Results Are In: Chi Rho Psi Recruited the Most Donors per Pledge • Mocktails \u27n More • Senior Class Update • Join the Army! • The Pressures Make us Miserable • De-Americanizing America • Infringing on a Conducive Learning Environment? • Why Keep Pushing? • My View on Abortion • The Million Man Exclusion • It is About Respect • In Need of Answers • Our Perspectives on Homosexuality • Homosexuality: Not an Alternative • Morality of Sexual Preference • Homecoming 1995 • Red & Gold Regulations • Mike Green Gives Advice on Drinking • Brendlinger Named Ursinus Assistant • Team Earns First Conference Win • Field Hockey Defeats Temple, Falls to American U. • Cross Country Competes in Allentown Invitational • Everyone is Invited! • Football Snaps Five-Game Skid • Steigerwalt Honoredhttps://digitalcommons.ursinus.edu/grizzlynews/1366/thumbnail.jp