7 research outputs found
Indications for ART Initiation in 222 children whose CD4 counts were above CD4 treatment thresholds.
<p><sup>a</sup> Not within the guidelines for ART initiation in children</p><p>Indications for ART Initiation in 222 children whose CD4 counts were above CD4 treatment thresholds.</p
Multivariate analysis of sex differences in CD4+ T cell recovery after initiating ART.
<p><sup>a</sup> HR: Hazard ratio</p><p><sup>b</sup> 95% confidential interval range</p><p><sup>c</sup> aHR: adjusted hazard ratio</p><p>Multivariate analysis of sex differences in CD4+ T cell recovery after initiating ART.</p
Proportion of HIV-infected children who were female in the subgroups analyzed within the Kimberley cohort.
<p>The proportion of female children in whom ART was initiated at CD4 counts higher than the CD4 thresholds compared to those in whom ART was initiated at CD4 counts lower than the CD4 thresholds differed significantly (p<0.001).</p
Sex differences in CD4+ T cell count, CD4% and viral load, amongst 2,101 ART-naĂŻve South African children.
<p>A. Absolute CD4 counts changes with age. B. CD4% changes with age. C. Viral load changes with age. In each panel, the solid lines are Loess-smoothed regression lines for female children and the dotted lines are Loess-smoothed regression lines for male children. A multivariable linear regression model, with both sex and age as covariates, shows significantly lower absolute CD4 counts in males (p = 0.005); significantly lower CD4% in males (p = 3.7x10<sup>-7</sup>); and no significant difference in viral load between the sexes.</p
Sex differences in immune reconstitution amongst the patients started treatment under the pre-2013 WHO guidelines.
<p>Sex differences by log rank test are shown as follows: A. Survival after ART initiation. B. CD4+ T cell percentage recovery (>35%) rate among the children who started ART aged 1–4 years old with CD4+ T cell <25%. C. Absolute CD4+ T cell count recovery (>750/ul) among children initiating ART aged ≥5 years old with absolute CD4+ T cell counts <350/ul.</p
Absolute CD4 count, CD4% and viral load in HIV-infected children and HIV-uninfected neonates.
<p><sup><b>a</b></sup> Mann Whitney test</p><p><u>HIV-Infected Children, n = 2,101</u>.</p
Study cohorts of HIV-infected South African children analyzed.
<p>Study cohorts of HIV-infected South African children analyzed.</p