Homemaker as Citizen

In a way German women are more enfranchized than the women of other countries. Not only that every female being from the age of twenty has a right to vote-the number of women in the Reichstag equally surpasses the representation of women in other parliamentary bodies, as it amounts to thirty-six in the present moment

External validation of models to estimate gestational age in the second and third trimester using ultrasound: A prospective multicentre observational study

Objectives: Accurate assessment of gestational age (GA) is important at both individual and population levels. The most accurate way to estimate GA in women who book late in pregnancy is unknown. The aim of this study was to externally validate the accuracy of equations for GA estimation in late pregnancy and to identify the best equation for estimating GA in women who do not receive an ultrasound scan until the second or third trimester. Design: This was a prospective, observational cross‐sectional study. Setting: 57 prenatal care centres, France. Participants: Women with a singleton pregnancy and a previous 11–14‐week dating scan that gave the observed GA were recruited over an 8‐week period. They underwent a standardised ultrasound examination at one time point during the pregnancy (15–43 weeks), measuring 12 foetal biometric parameters that have previously been identified as useful for GA estimation. Main Outcome Measures: A total of 189 equations that estimate GA based on foetal biometry were examined and compared with GA estimation based on foetal CRL. Comparisons between the observed GA and the estimated GA were made using R2, calibration slope and intercept. RMSE, mean difference and 95% range of error were also calculated. Results: A total of 2741 pregnant women were examined. After exclusions, 2339 participants were included. In the 20 best performing equations, the intercept ranged from −0.22 to 0.30, the calibration slope from 0.96 to 1.03 and the RSME from 0.67 to 0.87. Overall, multiparameter models outperformed single‐parameter models. Both the 95% range of error and mean difference increased with gestation. Commonly used models based on measurement of the head circumference alone were not amongst the best performing models and were associated with higher 95% error and mean difference. Conclusions: We provide strong evidence that GA‐specific equations based on multiparameter models should be used to estimate GA in late pregnancy. However, as all methods of GA assessment in late pregnancy are associated with large prediction intervals, efforts to improve access to early antenatal ultrasound must remain a priority. Trial Registration: The proposal for this study and the corresponding methodological review was registered on PROSPERO international register of systematic reviews (registration number: CRD4201913776)

The Iowa Homemaker vol.4, no.3-4

Table of Contents Canning and Its Bacteriology by Clarissa Clark, page 1 Book Binding for Summer Afternoons by Marvel Secor, page 2 Salads and Sandwiches by Ida Mae Shilling, page 3 Clothes for Tiny Tots by Harriet Allen, page 4 The Food with the Flower’s Flavor by Agnes Sorenson, page 5 “Thirty-five Cents Worth of Food” by Anna Sorenson, page 6 Once Upon a Time by Marvel Secor, page 6 Nutrition Work in Iowa by Viola Jammer, page 7 Pleasant, Practical Porches by Edna Armstrong, page 7 Homemaker as Citizen by Dr. Alice Salomon, page 8 Protein Foods of the Japanese by Sarah Field, page 9 Who’s There and Where by Helen Putnam, page 10 Editorial Page, page 11 The Eternal Question, page 12 National Story Contest by Grace V. Gray, page 13 Bits About Cheese by Katherine Holden, page 1

Simultaneous Magneto-Optical Trapping of Two Lithium Isotopes

We confine 4 10^8 fermionic 6Li atoms simultaneously with 9 10^9 bosonic 7Li atoms in a magneto-optical trap based on an all-semiconductor laser system. We optimize the two-isotope sample for sympathetic evaporative cooling. This is an essential step towards the production of a quantum-degenerate gas of fermionic lithium atoms.Comment: 4 pages, 3 figure

Regulation of Respiration and Apoptosis by Cytochrome c Threonine 58 Phosphorylation

Cytochrome c (cytc) is a multifunctional protein, acting as an electron carrier in the electron transport chain (ETC), where it shuttles electrons from bc1 complex to cytochrome c oxidase (COX), and as a trigger of type II apoptosis when released from the mitochondria. We previously showed that cytc is regulated in a highly tissue-specific manner: Cytc isolated from heart, liver, and kidney is phosphorylated on Y97, Y48, and T28, respectively. Here, we have analyzed the effect of a new Cytc phosphorylation site, threonine 58, which we mapped in rat kidney Cytc by mass spectrometry. We generated and overexpressed wild-type, phosphomimetic T58E, and two controls, T58A and T58I cytc; the latter replacement is found in human and testis-specific Cytc. In vitro, COX activity, caspase-3 activity, and heme degradation in the presence of H2o2 were decreased with phosphomimetic Cytc compared to wild-type. Cytc-knockout cells expressing T58E or T58I Cytc showed a reduction in intact cell respiration, mitochondrial membrane potential (∆Ψm), ROS production, and apoptotic activity compared to wild-type. We propose that, under physiological conditions, Cytc is phosphorylated, which controls mitochondrial respiration and apoptosis. Under conditions of stress Cytc phosphorylations are lost leading to maximal respiration rates, ∆Ψm hyperpolarization, ROS production, and apoptosis

Rabies, Still Neglected after 125 Years of Vaccination

International audienceno abstrac

Nanogap structures for molecular nanoelectronics

This study is focused on the realization of nanodevices for nano and molecular electronics, based on molecular interactions in a metal-molecule-metal (M-M-M) structure. In an M-M-M system, the electronic function is a property of the structure and can be characterized through I/V measurements. The contact between the metals and the molecule was obtained by gold nanogaps (with a dimension of less than 10 nm), produced with the electromigration technique. The nanogap fabrication was controlled by a custom hardware and the related software system. The studies were carried out through experiments and simulations of organic molecules, in particular oligothiophenes

Stoma-free survival after anastomotic leak following rectal cancer resection : worldwide cohort of 2470 patients

Funding Information: The TENTACLE-Rectum study was funded by Medtronic External Research Program. The authors declare no other conflict of interest.Peer reviewedPublisher PD