Statins inhibit the activation of Rho signaling, which negatively influences eNOS mRNA stability and activity, leading to an increased NO bioavailability

<p><b>Copyright information:</b></p><p>Taken from "The role of HMG-CoA reductase inhibition in endothelial dysfunction and inflammation"</p><p></p><p> 2007;3(5):567-577.</p><p>Published online Jan 2007</p><p>PMCID:PMC2291301.</p><p></p

Ang II and NO functions interplay to influence vascular tone, through different effects on RhoA pathway

<p><b>Copyright information:</b></p><p>Taken from "The role of HMG-CoA reductase inhibition in endothelial dysfunction and inflammation"</p><p></p><p> 2007;3(5):567-577.</p><p>Published online Jan 2007</p><p>PMCID:PMC2291301.</p><p></p