The Effects of the Roy’s Adaptation Model on Primigravida Women’s Self-Concept: A Randomized Controlled Trial

Most women do not have a positive self-concept and impression about themselves during pregnancy because they become less active and gain more weight. Self-concept significantly contributes to individuals’ mental health. This controlled trial was performed to assess the effect of an intervention based on the Roy’s adaptation model on self-concept among primigravida women. This study was conducted on a random sample of 83 Iranian primigravida women. Women in the experimental group received educational and counseling services in five sessions held in five consecutive weeks. Thereafter, they received a four-week follow-up care. Before the intervention, there were no significant differences between the two groups regarding adaptation knowledge and self-concept adaptation. However, after the intervention, these differences were statistically significant. The Roy’s adaptation model has positive effects on primigravida women’s physical and interpersonal self-concept adaptation. Given its simplicity and easy applicability, this model can be used for improving pregnancy-related outcomes

Impact of Roux-en-Y gastric bypass surgery on rat intestinal glucose transport

Roux-en-Y gastric bypass (RYGB) has become the gold-standard bariatric procedure, partly because of the rapid resolution of accompanying diabetes. There is increasing evidence this is mediated by duodenal exclusion. We hypothesize that duodenal exclusion suppresses intestinal Na+/glucose cotransporter SGLT1-mediated glucose transport, improving glucose handling, and aimed to test this in a rodent RYGB model. Sprague-Dawley rats underwent sham procedure or duodenal exclusion by RYGB (10 cm Roux, 16 cm biliopancreatic limbs). Animals were maintained for 3 wk on a Western diet, before harvest at 10 AM, 4 PM, and 10 PM. Sections were taken from each limb for hematoxylin and eosin staining, and morphological assessment was performed. Functional glucose uptake studies, along with Western blotting and quantitative PCR, were performed on Roux limb. Histology showed morphometric changes in Roux and common limbs, with increase in villus height and crypt depth compared with BP and sham jejunum. Despite this, glucose transport was reduced by up to 68% (P < 0.001) in the Roux limb compared with sham jejunum. Normal diurnal rhythms in glucose uptake were ablated. This occurred at a posttranscriptional level, with little change in message but appearance of different weight species of Sglt1 on Western blotting. We have shown duodenal exclusion significantly influences both intestinal structure and glucose transport function, with glucose absorptive capacity reduced after RYGB. This provides a novel mechanistic explanation for some of the antidiabetic effects of RYGB