Bibliometric analysis of amebiasis research

Aim: Amebiasis is a disease caused by protozoon Entamoeba histolytica, that results in amoebic dysentery. While intestinal parasites are the third leading cause of death, especially in developing countries, it has been of global concern. Bibliometric methods have been used in the parasitology discipline for more than 30 years, however there is not any bibliometric study on amebiasis in the literature. Our aim was to analyse the published literature on amebiasis by bibliometric methods. Material and methods: A systematic evaluation of the literature using the Scopus database was made from inception to 2021. The search terms ‘amebiasis’, ‘Entamoeba’, ‘Entamoeba histolytica’, and ‘amoebic dysentery’ were used. The authors, publication year, title, publishing country/journal/institution, title, keywords, and citation numbers were acquired for each article. Descriptive data analysis was conducted via Microsoft Excel 2010 and Scopus database’s graphics were used. Results: Among 7,140 articles, 18.9 % of them were published open access, and 72.75 % of them were in the English language. Most of the articles were from the area of medicine. The USA, Mexico, and India were the top leading countries. The number of publications did not fall below 50 per year since 1950. There was an increasing number of citations on amebiasis research recently. Conclusion: Amebiasis is a global concern as one of the leading infectious causes of mortality in developing countries. Bibliometric analysis has shown the growing attraction to the amebiasis research, so it will continue to be global public health issue. Key words: amebiasis, bibliometric analysis, Entamoeba histolytica, bibliometric

Giant serous microcystic pancreas adenoma

Serous cystadenomas are rare tumors comprising 1-2% of exocrine pancreas tumors. They are mostly known as benign conditions but malign transformation as serous cystadenocarcinoma is also reported. It is usually seen in females. Non-specific symptoms, such as abdominal pain or symptoms due to mass affect, are usually seen. A 64-year old female patient was investigated for abdominal pain. Physical and laboratory findings were normal. Abdomen ultrasonography confirmed an 11x9.5 cm solid cystic lesion and abdomen computed tomography scan confirmed a 12x11 cm lobulated cystic solid lesion which had central cystic necrotic areas extending from liver hilus inferiorly. Fine needle biopsy confirmed benign cytology and trucut biopsy of the pancreatic mass reported chronic inflamation. Nevertheless, this mass could have malignant contents and transformation potential. A laparatomy was decided due to patient's symptoms and mass effect. Due to vascular invasion of the tumor, Whipple procedure was performed. The pathology report confirmed serous microcystic adenoma. These rare tumors are usually benign but pre-operative malignity criterias are not identified. There are few differential diagnostic tools for excluding malignity. We suggest surgical resection as best treatment approach for selected cases

The 2nd to 4th Digit Length Difference and Ratio as Predictors of Hyperandrogenism and Metabolic Syndrome in Females

Objective: In this study we evaluated the usefulness of 2nd to 4th (2nd:4th) digit length difference and ratio in determining hyperandrogenism in females and the relationship with metabolic syndrome

The 2nd to 4th Digit Length Difference and Ratio as Predictors of Hyperandrogenism and Metabolic Syndrome in Females

WOS: 000363103000008Objective: In this study we evaluated the usefulness of 2nd to 4th (2nd:4th) digit length difference and ratio in determining hyperandrogenism in females and the relationship with metabolic syndrome. Methods: We designed a cross-sectional clinical study and examined 150 females who visited our clinic; 137 completed the study. We measured blood pressure and anthropometric values. Biochemical parameters associated with metabolic syndrome were also measured. Results: The mean age of our patient is 46.1 yrs. The 2nd:4th digit length difference and ratio were correlated slightly with total testosterone levels and positively with free testosterone levels (p=0.028, p=0.016, p=0.003, p=0.016). Sex hormone-binding globulin levels and 2nd:4th digit length difference and ratio were mildly negatively correlated (p=0.011, p=0.016). No statistically significant differences were found between 2nd:4th digit length difference and ratio, and metabolic syndrome parameters. Thus, the 2nd:4th digit length difference and ratio are significantly correlated with androgens. Conclusion: The 2nd:4th digit length difference and ratio, which are easily measurable values, can be used as an important predictor of hyperandrogenism in females. In the present study, 2nd:4th digit length difference and ratio were not statistically significantly correlated with metabolic syndrome; however, additional studies with a larger group of patients are necessary

Comparison of Fenestrating and Reconstituting Subtotal Cholecystectomy Techniques in Difficult Cholecystectomy.

PurposeCholecystectomy is one of the most frequently performed surgeries. Although laparoscopy is considered the gold standard approach, it cannot prevent biliary injuries. Subtotal cholecystectomy has been performed mainly to prevent biliary injuries during difficult cholecystectomies. This study aimed to analyse our subtotal cholecystectomy results for difficult cholecystectomy cases and to evaluate the fenestrating and reconstituting techniques.MethodsRetrospective data were collected and analysed statistically for cases that underwent subtotal cholecystectomy in a single referral centre between 2015 and 2020. Comparisons were made of the patients’ age, gender, preoperative American Society of Anaesthesiologists (ASA) score, comorbidities, surgical timing, surgical procedure choice, postoperative complications, and mortality.ResultsThe number of patients who underwent subtotal cholecystectomy was 46; 30.4% underwent emergent surgery and 69.6% underwent elective surgery. Twelve patients had subtotal fenestrating cholecystectomy and 34 had subtotal reconstituting cholecystectomy. Wound issues were noted in 17.4% of the patients, while 10.9% had temporary biliary fistulas that resolved spontaneously. Reoperation was performed in one patient due to high-output biliary drainage. Patients with postoperative complications had significantly higher co-morbid conditions (p=0.000), but surgery timing (p=0.192) and type of subtotal cholecystectomy (p=0.409) had no statistically significant effect on complications. Mortality showed a statistically significant correlation with patient comorbidities, surgery timing, and the type of procedure (p&lt;0.05). Postoperative complications showed a statistically significant correlation with mortality (p&lt;0.05).ConclusionSubtotal cholecystectomy prevents major biliary complications after cholecystectomy. Yet, the frequency of postoperative complications after subtotal cholecystectomy is incontrovertible. Intraoperative characteristics and the surgeon’s expertise decide the optimal choice of the subtotal cholecystectomy technique.</p