2 research outputs found

    As revoltas árabes e a democracia no mundo

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    Desde Kant que sabemos como a natureza dos regimes importa para a segurança internacional e como os povos “republicanos” tendem a ser mais pacíficos do que aqueles que vivem sob regimes despóticos ou autoritários. Nesse sentido, pode dizer-se que o estudo das mudanças políticas e o acompanhamento da evolução dos regimes nas várias regiões do globo é crucial para a análise das tendências e das ameaças e riscos à segurança nacional, e como tal inserem-se na missão do Instituto da Defesa Nacional (IDN). Foi justamente por isso que o IDN lançou uma linha de investigação sobre este tema e que, no dia 26 de Abril de 2012, organizou um seminário internacional intitulado “As Revoltas Árabes e a Democracia no Mundo”, com painéis sobre transições democráticas, a situação no mundo árabe e a promoção da democracia. O seminário contou com a intervenção de altos funcionários, antigos responsáveis políticos e académicos especializados em processos de democratização e na análise do mundo árabe e do Médio Oriente. Alguns desses oradores deixaram-nos ou enviaram-nos contributos escritos. São precisamente esses contributos que aqui se reúnem

    Evolution over Time of Ventilatory Management and Outcome of Patients with Neurologic Disease∗

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    OBJECTIVES: To describe the changes in ventilator management over time in patients with neurologic disease at ICU admission and to estimate factors associated with 28-day hospital mortality. DESIGN: Secondary analysis of three prospective, observational, multicenter studies. SETTING: Cohort studies conducted in 2004, 2010, and 2016. PATIENTS: Adult patients who received mechanical ventilation for more than 12 hours. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Among the 20,929 patients enrolled, we included 4,152 (20%) mechanically ventilated patients due to different neurologic diseases. Hemorrhagic stroke and brain trauma were the most common pathologies associated with the need for mechanical ventilation. Although volume-cycled ventilation remained the preferred ventilation mode, there was a significant (p < 0.001) increment in the use of pressure support ventilation. The proportion of patients receiving a protective lung ventilation strategy was increased over time: 47% in 2004, 63% in 2010, and 65% in 2016 (p < 0.001), as well as the duration of protective ventilation strategies: 406 days per 1,000 mechanical ventilation days in 2004, 523 days per 1,000 mechanical ventilation days in 2010, and 585 days per 1,000 mechanical ventilation days in 2016 (p < 0.001). There were no differences in the length of stay in the ICU, mortality in the ICU, and mortality in hospital from 2004 to 2016. Independent risk factors for 28-day mortality were age greater than 75 years, Simplified Acute Physiology Score II greater than 50, the occurrence of organ dysfunction within first 48 hours after brain injury, and specific neurologic diseases such as hemorrhagic stroke, ischemic stroke, and brain trauma. CONCLUSIONS: More lung-protective ventilatory strategies have been implemented over years in neurologic patients with no effect on pulmonary complications or on survival. We found several prognostic factors on mortality such as advanced age, the severity of the disease, organ dysfunctions, and the etiology of neurologic disease
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