An Analysis of the Physical and Cultural Landscape of Grand Isle, Louisiana

The town of Grand Isle, Louisiana, and its rich geographic history, can offer insight into the early history of the State of Louisiana and the establishment of the United States as a country, as well as the study of the formation of barrier islands and methods of land use with such areas. The following thesis presents a geographic, as well as a historical, analysis of Grand Isle’s history. It attempts to answer the following questions: What is the shape, form, and origin of the physical landscape of Grand Isle? How have humans interacted with the land and surrounding areas of Grand Isle? And what impacts, if any, have these interactions had on the island and its landscape? These questions include research into both the built environment and the natural environment

A Methodology for Three-Dimensional Quantification of Anterior Tooth Width

The use of cone-beam computed tomography (CBCT) technology has been shown to be more accurate in measuring individual incisor tooth widths than the use of wax exemplars. There were fewer differences by investigators using CBCT than others using an F-test in a mixed model of the measurement differences of investigators, wax type, and which tooth was measured. In addition, the frequency of outliers was less in the CBCT method (a total of 5) as compared to the two-dimensional measurements in ether Aluwax (a total of 8) or Coprwax (a total of 12). Both results indicate that CBCT measurements accounted more precisely for tooth width and level of eruption

The emerging role of Clostridium histolyticum collagenase in the treatment of Dupuytren disease

Dupuytren disease (DD) is a common fibroproliferative disease of unknown etiopathogenesis affecting the palmar aponeurosis, causing reduced hand function and resulting in fixed flexion contractures of the digits. Current gold standard treatment for the management of DD is surgical excision involving removal of the affected palmar fascial tissue. However, there are potential complications associated with surgery as it is costly and a positive surgical outcome is often short-lived because the disease tends to recur. Therefore, there is growing interest in nonsurgical, outpatient-based treatments that could be quicker, cheaper, reduce morbidity, show a decreased rate of recurrence, and give DD patients an improved quality of life when compared with traditional surgical management. Of the available nonsurgical options, injectable Clostridium histolyticum collagenase (CHC) has received recent clinical interest. In this article, a brief overview of DD surgical and nonsurgical treatments utilized is given, followed by a detailed examination of the nine papers published to date on the use of CHC in DD (and similar fibrotic disorders). These papers have investigated safe and efficacious doses for the injection of CHC to treat palpable DD cords in adult patients and have shown significant short- to mid-term results for correction to near-full digital extension (≤5° extension) following CHC injection of DD cords. CHC has been shown to target the collagen-based DD cords while sparing surrounding neurovasculature, with a complication profile that appears comparable to that of the surgical methods currently utilized. In conclusion, clostridial collagenase is a novel nonsurgical treatment option of considerable potential in the management of DD when administered by specialist hand surgeons with detailed knowledge of the disease and the relevant anatomy. Nonetheless, there is a need for further data on long-term results, complications, and rate of recurrence with the use of this emerging treatment option

Absorptive Capacity and Export Diversification in Sub-Saharan African Countries

This paper examines the extent to which dependence on primary commodities in Sub-Saharan African(SSA) countries can be explained by low levels of absorptive capacity (the ability to acquire, internalize and utilize knowledge developed elsewhere). We examine the individual and combined effects of various indicators of absorptive capacity on export diversification. We test the significance of these effects on a sub-sample consisting of SSA countries and a sample of other developing countries. Our results show that the association between higher levels human capital and basic infrastructure -two crucial components of absorptive capacity -with more export diversification is subject to threshold level effects, while the abundance of natural resources turns out to be impeding diversification in SSA. These results imply that SSA countries need to substantially increase their investments in basic infrastructure as well as reinforce the accumulation pace of human and physical capital to allow active technological learning and reduce their dependence on primary commodities.absorptive capacity, human capital, capital accumulation, export diversification, Sub-Saharan Africa.