Utilizarea principiilor recuperării medicale în practica veterinară

Recuperarea fizică este o terapie standard de îngrijire în medicina umană și s-a dovedit a maximiza recuperarea fizică a pacienților. Utilizată împreună cu tratamentul standard medical și chirurgical și gestionarea corectă a durerii, reabilitarea poate facilita recuperarea timpurie și mai completa. Progresul în medicina veterinară a dus la o speranță de viață mai mare pentru majoritatea animalelor de companie și diminuarea afecțiunilor cronice. Modalitățile de reabilitare fizică oferă opțiuni pentru tratament și ameliorarea simptomatică a acestor pacienți

Robustness Analysis for the Re-entrant Flow Shop Problem

Scheduling is required in almost every industry and when done well it can bring a lot of revenue. Flexibility is often forgotten when creating the initial schedules. Therefore, in case of an unexpected delay, the whole schedule has to suffer. In this paper, we consider a re-entrant flow shop with sequence-dependent setup times and relative due dates for our industrial partner, which specialises in industrial printers. Then, we perform a robustness analysis on real schedules from the industry, which can be extended to any system represented as a flow shop with relative due dates. We find how much time a schedule with relative due dates has before it becomes infeasible. We continue by empirically creating a new robustness measure and comparing it with state-of-the-art techniques. The experiments confirm that this measure can be useful in creating robust initial schedules for re-entrant flow shops with added idle time that has a minimal effect on the total duration of the solution.CSE3000 Research ProjectComputer Science and Engineerin

Low-Molecular-Weight Heparins (LMWH) and Synthetic Factor X Inhibitors Can Impair the Osseointegration Process of a Titanium Implant in an Interventional Animal Study

Background and objectives: Cementless total hip arthroplasty is a common surgical procedure and perioperative thromboprophylaxis is used to prevent deep vein thrombosis or pulmonary embolism. Osseointegration is important for long-term implant survival, and there is no research on the effect of different thromboprophylaxis agents on the process of osseointegration. Materials and Methods: Seventy rats were allocated as follows: Group I (control group), Group II (enoxaparin), Group III (nadroparin), and Group IV (fondaparinux). Ovariectomy was performed on all subjects, followed by the introduction of an intramedullary titanium implant into the femur. Thromboprophylaxis was administered accordingly to each treatment group for 35 days postoperatively. Results: Group I had statistically significantly lower anti-Xa levels compared to treatment groups. Micro-CT analysis showed that nadroparin had lower values compared to control in bone volume (0.12 vs. 0.21, p = 0.01) and percent bone volume (1.46 vs. 1.93, p = 0.047). The pull-out test showed statistically significant differences between the control group (8.81 N) compared to enoxaparin, nadroparin, and fondaparinux groups (4.53 N, 4 N and 4.07 N, respectively). Nadroparin had a lower histological cortical bone tissue and a higher width of fibrous tissue (27.49 μm and 86.9 μm) at the peri-implant area, compared to control (43.2 μm and 39.2 μm), enoxaparin (39.6 μm and 24 μm), and fondaparinux (36.2 μm and 32.7 μm). Conclusions: Short-term administration of enoxaparin, nadroparin, and fondaparinux can reduce the osseointegration of titanium implants, with nadroparin having the most negative effect. These results show that enoxaparin and fondaparinux are preferred to be administered due to a lesser negative impact on the initial implant fixation

Clinical Remission in a 72-Year-Old Patient with a Massive Primary Cutaneous Peripheral T-Cell Lymphoma-NOS of the Eyelid, Following Combination Chemotherapy with Etoposide Plus COP

Peripheral T-cell lymphoma not otherwise specified (PTCL-NOS) is the rarest subtype of primary cutaneous lymphoma, accounting for approximately 2% of cutaneous lymphomas. The rarity of primary cutaneous PTCL-NOS means that there is a paucity of data regarding clinical and histopathological features and its clinical course. This malignancy is an aggressive and life-threatening hematological malignancy that often presents mimicking other less severe plaque-like skin conditions. Due to the nonspecific nature of these lesions, CD4-positive cutaneous T-cell lymphoma (CTCL) is often misdiagnosed as either mycosis fungoides or Sezary syndrome. We describe a patient who presented with a large tumoral mass in the right frontal area, with involvement of the right upper eyelid and the ocular globe, causing loss of vision greatly impacting the quality of life. Biopsy revealed primary cutaneous PTCL-NOS, treated successfully with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) plus etoposide combination chemotherapy. As elderly patients are indicated to receive attenuated doses of chemotherapy, CHOP-based regimens represent viable options