2 research outputs found
Pleural effusions in Hematologic malignancies
Nearly all hematologic malignancies can occasionally present with or
develop pleural effusions during the clinical course of disease. Among
the most common disorders are Hodgkin and non-Hodgkin lymphomas, with a
frequency of 20 to 30%, especially if mediastinal involvement is
present. Acute and chronic leukemias, myelodysplastic syndromes, are
rarely accompanied by pleural involvement. Furthermore, 10 to 30% of
patients receiving bone marrow transplantation develop pleural
effusions. In cases of hematologic pleural effusions, drug toxicity,
underlying infectious, secondary malignant or rarely autoimmune causes
should be carefully sought. In most cases, the pleural fluid responds to
treatment of the primary disease, whereas resistant or relapsing cases
may necessitate pleurodesis