Individual and obstetrical characteristics of the women included in the study (n = 481).

<p>Individual and obstetrical characteristics of the women included in the study (n = 481).</p

Risk of preterm birth within 48 hours: Optimal threshold determination.

<p><b>On the left: In cohort 1</b>: To determine the best preterm risk threshold (minimization of false-negative and false-positive rates), one reliable statistical tool was used: MinROCdist. MinROCdist is the cut-off that minimizes the distance between the ROC curve and the upper left corner of the unit square. <b><i>On the right</i>: <i>In cohort 2</i>:</b> To determine the best preterm risk threshold (minimization of false-negative and false-positive rates), one reliable statistical tool was used: MinROCdist. MinROCdist is the cut-off that minimizes the distance between the ROC curve and the upper left corner of the unit square.</p

Characteristics of infants according to the occurrence of readmission for wheezing.

<p>Total number of children analyzed in each subgroup is specified, if different from the total number available.</p

Kaplan—Meier analysis to estimate freedom from re-hospitalization.

<p>Kaplan—Meier analysis to estimate freedom from re-hospitalization.</p

Characteristics of first and second readmissions for wheezing.

<p>The total number of children analyzed in each subgroup is specified if it differs from the total number available.</p

Readmissions among children with CDH, between hospital discharge and 24 months of age.

<p>The number of children who were readmitted zero, one, two, or three or more times is shown. Black columns correspond to hospitalizations for any cause, and white columns correspond to hospitalizations for wheezing exacerbations. The total number of children evaluated is n = 86.</p

A: Correlation between the two UA-PIs measured at the perivesical (PVC) segment.

<p>The larger UA-PI value of the pair was designated PVC-UA-PI_max and the smaller, PVC-UA-PI_min. The dotted line depicts the line of equality. B: Comparison between the UA-PI measured at the PVC segment and in the free-floating cord (FFC). </p

Hemodynamic Impact of Absent or Reverse End-Diastolic Flow in the Two Umbilical Arteries in Growth-Restricted Fetuses

<div><p>Objective</p><p>To determine if bilateral absent or reverse end-diastolic (ARED) flow in the two umbilical arteries (UAs) at the perivesical (PVC) segment represents a more severe degree of hemodynamic compromise than unilateral ARED flow at the PVC segment in singleton pregnancies complicated by intrauterine growth restriction (IUGR).</p> <p>Methods</p><p>This was a prospective observational study. One hundred nine fetuses with IUGR underwent a total of 225 ultrasound (US) examinations. We measured the pulsatility index (PI) from the two UAs at the PVC segment, UA in the free floating cord (FFC), middle cerebral artery (MCA), ductus venosus (DV) and the aortic isthmus blood flow index (IFI). Three groups were classified according to bilateral positive end-diastolic (PED) flow, unilateral ARED flow or bilateral ARED flow in the UAs at the PVC segment.</p> <p>Results</p><p>The proportions of US examinations with PED flow, unilateral ARED flow and bilateral ARED flow in the UAs were 54.7%, 20.4%, and 24.9%, respectively. At the last US examination, the IFI z-scores were significantly lower in the bilateral ARED group (-6.28±4.30) compared to the unilateral ARED group (-1.72±3.18, p<0.05) and the bilateral PED group (-0.83±2.36, p<0.05), the DV-PI z-scores were significantly higher in the bilateral ARED group (2.15±3.79) compared to the bilateral PED group (0.64±1.50, p<0.05). Before 32 weeks of gestation, the interval between US examination and delivery was significantly shorter in the bilateral ARED group (8.9 days ±8.2) than the unilateral ARED group (15.9 days ±13.4, p<0.05) and the bilateral PED group (30.3 days±25.7, p<0.05).</p> <p>Conclusion</p><p>There are significant differences in fetal blood fluxes between left and right UA. Doppler examination at the PVC segment significantly improves the comparability of UA-PI between two successive US examinations and allows a longitudinal and independent hemodynamic investigation of each UA. Examination of a single UA in free floating cord may miss a large fraction of unilateral ARED flow. In singleton IUGR fetuses, a bilateral ARED flow in the UAs at the PVC segment indicates more severe hemodynamic compromise and worse fetal conditions than unilateral ARED flow.</p> </div

Sensitivity and specificity of MRI features.

<p>Sensitivity and specificity of MRI features.</p

Uterine bulging and disruption of the hyperechogenic uterine serosa-bladder wall interface on ultrasonography.

<p>Uterine bulging and disruption of the hyperechogenic uterine serosa-bladder wall interface on ultrasonography.</p