Task 1 (active regulation).

<p>Upper row left: Amygdala activation was significantly attenuated during regulation (p<0.05 FWE corrected for ROI). This regulation related decrease of amygdala activation was positively correlated with a regulation related increase in DLPFC activation (Upper row, right). Bottom row, left: Time course of left Amygdala, showing a significant postregulation rebound and a significant interaction of regulation and period (bar plot bottom row, middle). Note: all effects here shown for the left amygdala, are also significant for the right amygdala. Bottom row, right: Positive correlation between peak activation during relax period (rebound) in left amygdala and individual scores in the WBSI.</p

Results of Task 2 (Passive Viewing).

<p>All results: p<0.05 FWE corrected for multiple comparisons; ^*p<0.05 FWE corrected for region of interest; BA Brodmann area; x,y,z, respective coordinates of MNI template.</p

Results of Task 1 (Active Regulation).

<p>All results: p<0.05 FWE corrected for multiple comparisons; ^*p<0.05 FWE corrected for region of interest; BA Brodmann area; x,y,z, respective coordinates of MNI template.</p

Task 2 (passive viewing).

<p>Upper row: Sustained downregulation of amygdala activation for formerly regulated negative pictures (p<0.05 FWE corrected for ROI; this effect was also significant for the left amygdala (not shown here)). Bottom row: Amygdala activation during presentation of formerly regulated negative pictures in task 2 correlated positively with individual differences in peak rebound activation in task 1 (p<0.05, FWE corrected for ROI; this effect was also significant at a lower statistical level (p = 0.008 uncorrected) for the left amygdala (not shown here)).</p