1 research outputs found
Ultrastable and Biofunctionalizable Gold Nanoparticles
Gold nanoparticles provide an excellent
platform for biological
and material applications due to their unique physical and chemical
properties. However, decreased
colloidal stability and formation of irreversible aggregates while
freeze-drying nanomaterials limit their use in real world applications.
Here, we report a new generation of surface ligands based on a combination
of short oligo (ethylene glycol) chains and zwitterions capable of
providing nonfouling characteristics while maintaining colloidal stability
and functionalization capabilities. Additionally, conjugation of these
gold nanoparticles with avidin can help the development of a universal
toolkit for further functionalization of nanomaterials