The synthesis of Androgen and Estrogen from cholesterol presented as a SBGN diagram

<p>A pathway diagram describing the synthesis of androgens and estrogens from cholesterol, obtained from a review of the published literature as part of the project work for our MSc in Genomics and Pathway Biology.  The pathway is presented in SBGN notation.  This pathway diagram has not been peer reviewed. </p

Oxysterol metabolism and regulation presented as a SBGN diagram

<p>A pathway diagram describing the regulation of oxysterol metabolim, obtained from a review of the published literature as part of the project work for our MSc in Genomics and Pathway Biology.  The pathway is presented in SBGN notation.  This pathway diagram has not been peer reviewed. </p

The Vitamin D3 Synthesis Pathway

<p>A pathway diagram describing the synthesis of vitamin D3 and its relationship to the cholesterol synthesis pathway, obtained from a review of the published literature as part of the project work for our MSc in Genomics and Pathway Biology. The pathway is presented in SBGN notation. This pathway diagram has not been peer reviewed.</p

Initial Analysis of Tumour Necrosis Factor alpha Promotor Activation by Interferon gamma using Boolean Logic Modelling

<p>A report produced as part of the MSc in Genomics and Pathway Biology course at the Division of Pathway Medicine, University of Edinburgh. (http://www.ed.ac.uk/schools-departments/pathway-medicine).  Note, that this has not been peer-reviewed.</p

Mapping innate immune host and viral gene interactions in monocytes/macrophages, in particular for IL1β and the LTR region of HIV-1

<p>Pathway diagrams describing the regulation of Interferon-beta and the Major Immediate Early Promotor (MIE) of human Cytomegalovirus, obtained from a review of the published literature as part of the project work for our MSc in Genomics and Pathway Biology. The pathways are presented in SBGN notation. This document has not been peer reviewed.</p

Examining common transcription factors and functional sequences that might indicate viral mimicry between the activation of Human Papilloma Virus-18 proteins E6 and E7 and the innate immune genes IRF1 and IL12

<p>Pathway diagrams describing the regulation of Interferon Regulatory Factor-1 (IRF1), Interleukin-12 (IL12) and Human Papilloma Virus-18 (proteins E6 and E7, HPV-18 E6, E7), obtained from a review of the published literature as part of the project work for our MSc in Genomics and Pathway Biology. The pathways are presented in SBGN notation. This document has not been peer reviewed.</p

Additional file 5: of Representing and querying disease networks using graph databases

Cypher query on the relationships between a) the O15534 protein (PER gene) and b) the P20393 protein (REV/ERBalpha gene) and the core clock genes, (Table 3). (DOCX 77 kb

Transcription factors of Interleukin-1β (IL-1β) are important for enhancer of Human Immunodeficiency Virus Type 1 Long Terminal Repeat sequence (HIV-1 LTR)

<p>Pathway diagrams describing the regulation of activation for Interleukin-8 (IL-1b) and Human Immunodeficiency Virus Type 1 long terminal repeat (HIV-1 LTR), obtained from a review of the published literature as part of the project work for our MSc in Genomics and Pathway Biology. The pathways are presented in SBGN notation. This document has not been peer reviewed. </p

Additional file 4: of Representing and querying disease networks using graph databases

Information on genes related to a simple disease only, as reported in [23]. (DOCX 120 kb

Additional file 1: of Representing and querying disease networks using graph databases

Disease-associated genes used in the study (from [23]). (DOCX 93 kb