New cassettes for single-step drug-resistance and prototrophic marker switching in fission yeast

Copyright © 2015 John Wiley & Sons, Ltd. Funded by College of Life Science and Medicine, University of Aberdeen, UK This work was funded by a start-up grant from the College of Life Science and Medicine, University of Aberdeen, UK. I am grateful to J. Bähler, E. Hartsuiker, F. Klein, J. Kohli, K. Nasmyth, M. C. Whitby, the Leibniz Institute – German Collection of Microorganisms and Cell Cultures (DMSZ) and the National BioResource Project Japan (NBRP) for providing materials used in this study. I thank Alistair J. P. Brown and Takashi Kubota for critically reading this manuscript.Peer reviewedPostprin

Candida auris : The path of yeast resistance

Non peer reviewedPublisher PD

A failure of meiotic chromosome segregation in a fbh1Δ mutant correlates with persistent Rad51-DNA associations

Peer reviewedPublisher PD

Rad51/Dmc1 paralogs and mediators oppose DNA helicases to limit hybrid DNA formation and promote crossovers during meiotic recombination

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. ACKNOWLEDGMENTS We are grateful to J ¨urg Kohli, Ramsay J. McFarlane, Paul Russell, Gerald R. Smith, Walter W. Steiner and the National BioResource Project (NBRP) Japan for providing strains and to C. Bryer for technical assistance. FUNDING Wellcome Trust [090767/Z/09/Z to M.C.W.]; College of Life Sciences and Medicine, University of Aberdeen [to A.L., in part]. Funding for open access charge: Wellcome TrustPeer reviewedPublisher PD

Asymptotic Entropy of Random Walks on Regular Languages over a Finite Alphabet

We prove existence of asymptotic entropy of random walks on regular languages over a finite alphabet and we give formulas for it. Furthermore, we show that the entropy varies real-analytically in terms of probability measures of constant support, which describe the random walk. This setting applies, in particular, to random walks on virtually free groups.Comment: 47 pages, 2 figure

Radiation Generated by Charge Migration Following Ionization

Electronic many-body effects alone can be the driving force for an ultrafast migration of a positive charge created upon ionization of molecular systems. Here we show that this purely electronic phenomenon generates a characteristic IR radiation. The situation when the initial ionic wave packet is produced by a sudden removal of an electron is also studied. It is shown that in this case a much stronger UV emission is generated. This emission appears as an ultrafast response of the remaining electrons to the perturbation caused by the sudden ionization and as such is a universal phenomenon to be expected in every multielectron system.Comment: 5 pages, 4 figure

On design studies for the future 50 GeV arrays of imaging air Cherenkov telescopes

Arrays of imaging air Cherenkov telescopes (IACTs) like VERITAS, HESS have been recently proposed as the instruments of the next generation for ground based very high energy gamma-ray astronomy invading into 50-100 GeV energy range. Here we present results of design studies for the future IACT arrays which have been performed by means of Monte Carlo simulations. We studied different trigger strategies, abilities of cosmic ray rejection for arrays of 4 and 16 telescopes with 10 m reflectors, equipped with cameras comprising 271 and 721 pixels of 0.25 and 0.15 degree, respectively. The comparative analysis of the performance of such telescope arrays has been done for both camera options, providing almost the same field of view of 4.3 degree. An important issue is the choice of the optimum spacing between the telescopes in such an array. In order to maximize the signal-to-noise ratio in observations at the small zenith angles of 20 degree as well as at large zenith angles of 60 degree, different arrangements of IACT array have been examined. Finally, we present a major recommendations regarding the optimum configuration.Comment: 5 pages, presented at the VERITAS Workshop on TeV Astrophysics of Extragalactic Sources, eds. M. Catanese, J. Quinn, and T. Weekes, to be published in Astroparticle Physic