Relative myelin water fraction change post-injury.

<p>Change scores for myelin water fraction, relative to baseline, plotted against time for each subject with a mild traumatic brain injury in all significant voxels A) across the whole brain; B) in the splenium of the corpus callosum (a structure most commonly affected in mild TBI). Dots represent data points for each injured athlete (mean ± standard error plotted in grey). Note: time zero refers to baseline.</p

Brain areas with significantly reduced myelin water fraction.

<p>Areas of significantly reduced myelin water fraction in athletes with concussion at two weeks post-injury, superimposed on a standard brain. These areas include the splenium of the corpus callosum, right posterior thalamic radiation, left superior corona radiata, left superior longitudinal fasciculus, and left posterior limb of the internal capsule.</p

Representative myelin water fraction maps.

<p>Myelin water fraction maps from a concussed athlete at baseline (left) and two weeks post-injury (right). Myelin water fraction is measured as the T2 signal from 0–40 ms divided by the total T2 signal. A region of the corpus callosum with a visible reduction in MWF post-injury is highlighted by the red arrow.</p

Demographic Characteristics for All Athletes.

<p>Demographic Characteristics for All Athletes.</p