14 research outputs found
The Spectrum of Yang Mills on a Sphere
In this note, we determine the representation content of the free, large N,
SU(N) Yang Mills theory on a sphere by decomposing its thermal partition
function into characters of the irreducible representations of the conformal
group SO(4,2). We also discuss the generalization of this procedure to finding
the representation content of N=4 Super Yang Mills.Comment: 18 pages v2. references added. typos fixe
Synchrotron-Derived Vibrational Data Confirm Unprotonated Oxo Ligand in Myoglobin Compound II
Significant Delay of Lethal Outcome in Cancer Patients Due to Peroral Administration of Bacillus oligonitrophilus KU-1
Treatment of cancer patients remains a serious medical problem and the development of alternative treatment strategies is therefore of great importance. In this connection, we developed a new bacterial-based, anticancer method. Ten cancer patients (three males, seven females) were involved in this study. Bacterial suspension of stationary phase Bacillus oligonitrophilus KU-1 was used as a remedy for peroral administration. In five patients, side effects (sicchasia, slight blood, and intracranial pressure gain) were detected, but all patients showed significant delay of lethal outcome without serious side effects. In conclusion, the suggested method was, in our opinion, a good alternative to conventional chemo-and radiotherapy techniques. In order to evaluate its efficiency for various tumors, a double-blind, placebo-controlled, multicenter study is needed
Significant Delay of Lethal Outcome in Cancer Patients Due to Peroral Administration of Bacillus oligonitrophilus KU-1
Nuclear resonance vibrational spectra of five-coordinate imidazole-ligated iron(II) porphyrinates
Nuclear resonance vibrational spectra have been obtained for six five-coordinate imidazole-ligated iron(II) porphyrinates, [Fe(Por)(L)] (Por = tetraphenylporphyrinate, octaethylporphyrinate, tetratolylporphyrinate, or protoporphyrinate IX and L = 2-methylimidazole or 1,2-dimethylimidazole). Measurements have been made on both powder and oriented crystal samples. The spectra are dominated by strong signals around 200\u2013300 cm\u20131. Although the in-plane and out-of-plane vibrations are seriously overlapped, oriented crystal spectra allow their deconvolution. Thus, oriented crystal experimental data, along with density functional theory (DFT) calculations, enable the assignment of key vibrations in the spectra. Molecular dynamics are also discussed. The nature of the Fe\u2013NIm vibrations has been elaborated further than was possible from resonance Raman studies. Our study suggests that the Fe motions are coupled with the porphyrin core and peripheral groups motions. Both peripheral groups and their conformations have significant influence on the vibrational spectra (position and shape).Peer reviewed: YesNRC publication: Ye
Effects of Imidazole Deprotonation on Vibrational Spectra of High-Spin Iron(II) Porphyrinates
The effects of the deprotonation
of coordinated imidazole on the vibrational dynamics of five-coordinate
high-spin iron(II) porphyrinates have been investigated using nuclear
resonance vibrational spectroscopy. Two complexes have been studied
in detail with both powder and oriented single-crystal measurements.
Changes in the vibrational spectra are clearly related to structural
differences in the molecular structures that occur when imidazole
is deprotonated. Most modes involving the simultaneous motion of iron
and imidazolate are unresolved, but the one mode that is resolved
is found at higher frequency in the imidazolates. These out-of-plane
results are in accord with earlier resonance Raman studies of heme
proteins. We also show the imidazole vs imidazolate differences in
the in-plane vibrations that are not accessible to resonance Raman
studies. The in-plane vibrations are at lower frequency in the imidazolate
derivatives; the doming mode shifts are inconclusive. The stiffness,
an experimentally determined force constant that averages the vibrational
details to quantify the nearest-neighbor interactions, confirms that
deprotonation inverts the relative strengths of axial and equatorial
coordination