Spring waters and the birth of a civilization, sacred waters of Roman Forum, physical chemical analysis of the sources in the III millennium, preliminary measurements

Lot of ancient cities born “around” a water spring; Be’er Sheva, the city of seven wells, מעיין הגיחון the Gihon in Jerusalem, Sulukulekap the Water-Tower Gate of Constantinople, the Kallirroe in Athens (born of Nymphs divinity), the Peirene in Corinth are some examples but surely Rome must be considered one of the city richest of springs. Thank to the presence of Tiber, from 1000 B.C. Romans had a great availability of water sources, 23 historically identified up today. The demographic increase (someone talks about more then 1 million citizens in the golden age) has led to a greater demand for water; so, in 312 B.C., the first Romans aqueduct was constructed and the water sources inside the Forum (cultural and government centre of Rome), as Juturnae, Tullianum, Lacus Curtius, became sacred. This paper treats a research inserted in a wider project aiming to compare different spring waters emerging in the area of the Roman Forum (Rome, Italy). In particular, data from in situ (Temperature, pH, Conductivity) and in-lab (anions and cations content) measures obtained in two campaigns in 2017, that compare nine sources and two nearby standpipes, are reported and discussed. From the preliminary results, the sacred springs seem quite different from Roman’s supply water; unfortunately, today, they are only resurgence, and in some cases, the flow is so low to be difficult to measure. The microbiological quality and a continuous monitoring of at least one of the sources will be the next step of the research project

Role of dopaminergic neurotransmission in pathophysiology of action tremor in Parkinson's disease

Rest tremor (RT), a tremor that occurs in a body part that is completely supported against gravity, is together with rigidity and bradykinesia among the core features of Parkinson's disease (PD). In addition to classical RT, many PD patients also have action tremor (AT) occurring during sustained postures or voluntary movement. Earlier studies showed a good correlation between striatal dopamine transporter (DAT) binding, measured with [(123)I] FP-CIT SPET and bradykinesia. By contrast, neither rigidity nor rest tremor seems to be closely related to the degree of dopaminergic denervation as measured by DAT imaging. Little is known about the relationship, if any, between the severity of action tremor and striatal DAT binding