Interaction between <i>DRD2</i> rs1076560 and <i>CHNRA5</i> rs16969968 on prefrontal gray matter volume.

<p>3Dimensional rendering (left, image thresholded at p<0.005, uncorrected) and mean ±0.95 CIs of gray matter content (right) of the interaction between <i>DRD2</i> rs1076560 and <i>CHNRA5</i> rs16969968 on DLPFC gray matter.</p

Correlation between BOLD fMRI in prefrontal cortex and Working Memory accuracy in <i>CHRNA5</i>-GA/<i>DRD2</i>-GT subjects.

<p>3Dimensional rendering (left, image thresholded at p<0.005, uncorrected) of the correlation between BOLD response in DLPFC and percentage of correct responses at 2-Back task in <i>CHRNA5</i>-GA/<i>DRD2</i>-GT subjects. On the right, relative scatterplot is shown indicating individual data points.</p

Interaction between <i>DRD2</i> rs1076560 and <i>CHNRA5</i> rs16969968 on prefrontal physiology at 2-Back.

<p>3Dimensional rendering (left, image thresholded at p<0.005, uncorrected) and mean ±0.95 CIs of BOLD response (right) of the interaction between <i>DRD2</i> rs1076560 and <i>CHNRA5</i> rs16969968 on working memory DLPFC activity.</p

Interaction between Working Memory behavioral performance, <i>DRD2</i> rs1076560 and <i>CHNRA5</i> rs16969968 genotypes.

<p>Mean ± Standard Errors correct responses (<i>DRD2</i>-GG, left panel; <i>DRD2</i>-Tcarriers, right panel) showing the interaction between the two genotypes. See text for statistics.</p

Results of exploratory uncorrected whole brain statistics (p<0.001, k = 10) showing the main effect of <i>DRD2</i> and its interaction with <i>CHRNA5</i> on brain physiology at 2-Back WM Task.

<p>Results of exploratory uncorrected whole brain statistics (p<0.001, k = 10) showing the main effect of <i>DRD2</i> and its interaction with <i>CHRNA5</i> on brain physiology at 2-Back WM Task.</p

Results of exploratory uncorrected whole brain statistics (p<0.001, k = 10) showing the main effect of genotypes and their interaction on gray matter volume.

<p>Results of exploratory uncorrected whole brain statistics (p<0.001, k = 10) showing the main effect of genotypes and their interaction on gray matter volume.</p

Demographics (±SD) and genetics of the samples included in the experiments performed.

<p>Demographics (±SD) and genetics of the samples included in the experiments performed.</p