121 research outputs found
Using Quantitative and Qualitative Methods to Pretest the Publication Take Charge of Your Diabetes: A Guide for Care
Quantitative and qualitative methods used to pretest the guidebook Take Charge of Your Diabetes: A Guide for Care are presented in this paper. Questionnaires were used as the quantitative method (completed by 59 diabetes educators and 301 people with diabetes) and focus groups were used as the qualitative method (3 groups composed of 22 black men and women with diabetes) to examine the relevance, purpose, content, and presentation of the Guide. Findings from between-methods triangulation supported the relevance, clarity Of messages, identification of groups that would be most likely to benefit, readability, understandability, and credibility of the Guide. Specific areas that needed modification were identified. Each evaluation method provided unique data; for example, quantifiable data on intention to change behavior was provided from one method and a recommendation that diversity be maintained was provided from the other method, The relative strengths and limitations of combining quantitative and qualitative approaches are described.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68540/2/10.1177_014572179602200608.pd
Confronting the issues of patient safety and investigator conflict of interest in an international clinical trial of myocardial reperfusion
The Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries (GUSTO) trial is a large scale international trial of new myocardial reperfusion strategies. The primary hypothesis is that early and sustained coronary artery recanalization will be associated with a significant reduction in mortality. The four regimens that are being tested are 1) streptokinase with subcutaneous heparin; 2) streptokinase with intravenous heparin; 3) accelerated recombinant tissue-type plasminogen activator (rt-PA) with intravenous heparin; and 4) combination streptokinase, rt-PA and intravenous heparin. The planned recruitment of 41,600 patients in 1,500 sites from 15 countries is expected to be completed by December 1992 and will enable detection of a 15% reduction or 1% absolute difference in mortality compared with that associated with standard therapy (streptokinase and subcutaneous heparin). In designing the trial, two important issues were directly addressed. First, a strategy was developed to provide assurance of patient safety during large scale investigational use of an aggressive thrombolytic regimen. This includes fascimile transmission of a one-page safety summary form to the Data Coordinating Center within 24 h of death or discharge, acceptance of the concept of "net clinical benefit" and close surveillance of the trial's progress by the independent Data and Safety Monitoring Committee. S
Prevention plus.
Latest issue consulted: 3 (1991).Description based on: 2 (1989).Mode of access: Internet
Alcohol research : meeting the challenge.
Shipping list no.: 86-194-P.Mode of access: Internet
ADAMHA news.
Title from caption.None published, July-Aug. 1992.Mode of access: Internet
NDATUS instruction manual : 1982 national drug and alcoholism treatment utilization survey.
Limited cataloging.Mode of access: Internet
"Just say no" clubs resource paper.
Shipping list no.: 86-711-P.Caption title.Mode of access: Internet
Self-run, self-supported houses for more effective recovery from alcohol and drug addiction : recovery, responsibility, replication : technical assistance manual for implementation of the Group Recovery Homes Provision of the Anti-Drug Abuse Act of 1988.
Latest issue consulted: 1992.Description based on: 1990.Mode of access: Internet
Alcohol, drug abuse, mental health, research grant awards /
Title varies slightly.Mode of access: Internet.Vols. for 1973-1979 prepared by: National Institute of Mental Health, Division of Extramural Research Programs, Program Analysis and Evaluation Section; 1980-198 by: Office of Extramural Programs, ADAMHA; 198 by: Office of Science, Alcohol, Drug Abuse, and Mental Health Administration; by: Division of Program Analysis, Office of Extramural Programs
DHHS publication no. (ADM).
Series consists of publications by the Alcohol, Drug Abuse and Mental Health Administration.Mode of access: Internet
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