Effects of a Multicomponent Exercise Program on Prevalence and Severity of the Frailty Syndrome in a Sample of Italian Community-Dwelling Older Adults

Background: Frailty is a well-known condition that leads to a lack of resilience, with a reduced homeostatic capacity and a consequent higher risk of suffering adverse health outcomes. This study investigated the effectiveness of an exercise program to improve and reverse physical frailty amongst Italian older adults. Methods: One hundred and twenty-three community dwelling older adults (mean age 74 years, SD = 6; 64% women) were involved in an experimental (EG; n = 62) and a control (CG; n = 61) group. Frailty was assessed at baseline and after the intervention using an adapted version of the frailty phenotype. The EG took part in a 16-week exercise program, consisting of endurance, strength, balance and flexibility exercises, while the CG maintained the same routine. Results: After the exercise program, the EG was more robust than the CG (F = 43.51, p < 0.001). Within the EG, 46% of pre-frail and 50% of frail people reached the robust and pre-frail levels, respectively. Effects of training were higher in frail and pre-frail people (reduction of frailty of 0.67 and 0.76 points, respectively) compared to robust ones (who frailty levels increased by 0.23 points; F = 11.32, p < 0.001). Conclusions: A multicomponent exercise program may be effective at improving and reverting frailty, specifically for frail and pre-frail people

The Daily Mile is able to improve cardiorespiratory fitness when practiced three times a week

The Daily Mile is a promising initiative aimed at removing some of the barriers to physical activity in the school setting. This quasi-experimental study investigated the dose\u2013effect of The Daily Mile on cardiorespiratory fitness, waist-to-height ratio, and body mass index (BMI) after a period of 3- and 6-months. A total of 279 students (mean age = 9 \ub1 1 years) participated in The Daily Mile while 269 students (mean age = 9 \ub1 1 years) did not (control group). A posteriori, the classes performing The Daily Mile on average two times per week were included in the 2_times subgroup, while those performing the activity on average three times per week in the 3_times subgroup. A significant difference was observed in favor of the experimental compared to the control group in the 6 Minute Run Test (F = 13.932, p = 0.008). Moreover, the improvement of the 6-minute run test was more pronounced for 3_times (effect size = 0.51) rather than for the 2_times subgroup (effect size = 0.29). No differences were observed in waist-to-height ratio and BMI scores. In conclusion, teachers are strongly recommended to implement The Daily Mile at least three times a week to see appreciable effects on cardiorespiratory fitness

Neural and contractile determinants of burst-like explosive isometric contractions of the knee extensors

Walking and running are based on rapid burst-like muscle contractions. Burst-like contractions generate a Gaussian-shaped force profile, in which neuromuscular determinants have never been assessed. We investigated the neural and contractile determinants of the rate of force development (RFD) in burst-like isometric knee extensions. Together with maximal voluntary force (MVF), voluntary and electrically evoked (8 stimuli at 300 Hz, octets) forces were measured in the first 50, 100 and 150 ms of burst-like quadriceps contractions in 24 adults. High-density surface electromyography (HDsEMG) was adopted to measure the root mean square (RMS) and muscle fiber conduction velocity (MFCV) from the vastus lateralis and medialis. The determinants of voluntary force at 50, 100 and 150 ms were assessd by stepwise multiple regression analysis. Force at 50 ms was explained by RMS (R2 = 0.361); force at 100 ms was explained by octet (R2 = 0.646); force at 150 ms was explained by MVF (R2 = 0.711) and octet (R2 = 0.061). Peak RFD (which occurred at 60 ± 10 ms from contraction onset) was explained by MVF (R2 = 0.518) and by RMS50 (R2 = 0.074). MFCV did not emerge as a determinant of RFD. Muscle excitation was the sole determinant of early RFD (50 ms), while contractile characteristics were more relevant for late RFD (≥100 ms). As peak RFD is mostly determined by MVF, it may not be more informative than MVF itself. Therefore, a time-locked analysis of RFD provides more insights into the neuromuscular characteristics of explosive contractions

Subjective versus objective measure of physical activity: a systematic review and meta-analysis of the convergent validity of the physical activity questionnaire for children (PAQ-C)

This study aimed to highlight the relationship between moderate-to-vigorous physical activity (MVPA) as assessed by accelerometer devices and the Physical Activity Questionnaire for Children (PAQ-C) to estimate the convergent validity of the questionnaire. A systematic review and a meta-analysis were applied by collecting pertinent studies (PubMed,Web of Science, PsycINFO, and SCOPUS) from 1997 until November 2020. The relationship between PAQ-C and MVPA scores was estimated considering correlation coefficients such as the effect size. Fisher\u2019s transformation was used to convert each correlation coefficient into an approximately normal distribution. The pooled correlations between PAQ-C and MVPA scores were measured by r values after converting the Fisher\u2019s z values back into correlation coefficients for presentation. A total of 13 studies were included in the meta-analysis, and a random effects model was adopted. The pooled correlation between PAQ-C and MVPA scores was significant but with a moderate effect size (r = 0.34 [0.29, 0.39], Z = 15.00, p &lt; 0.001). No heterogeneity among the studies was observed (I2 &lt; 25%). In conclusion, the results highlighted a moderate relationship (around 0.30\u20130.40) between PAQ-C and accelerometer measurements. These results suggested to concurrently administer both tools to reach a more comprehensive description of children\u2019s PA, in terms of quality and quantity

Motor unit discharge rate and the estimated synaptic input to the vasti muscles is higher in open compared with closed kinetic chain exercise

Conflicting results have been reported on whether closed kinetic chain exercises (such as a leg press) may induce more balanced activation of vastus medialis (VM) and lateralis (VL) muscles compared with open kinetic chain exercise (such as pure knee extension). This study aimed to 1) compare between-vasti motor unit activity and 2) analyze the combined motor unit behavior from both muscles between open and closed kinetic chain exercises. Thirteen participants (four women, mean ± SD age: 27 ± 5 yr) performed isometric knee extension and leg press at 10, 30, 50, 70% of the maximum voluntary torque. High density surface EMG signals were recorded from the VM and VL and motor unit firings were automatically identified by convolutive blind source separation. We estimated the total synaptic input received by the two muscles by analyzing the difference in discharge rate from recruitment to target torque for motor units matched by recruitment threshold. When controlling for recruitment threshold and discharge rate at recruitment, the motor unit discharge rates were higher for knee extension compared with the leg press exercise at 50% [estimate = 1.2 pulses per second (pps), standard error (SE) = 0.3 pps, P = 0.0138] and 70% (estimate = 2.0 pps, SE = 0.3 pps, P = 0.0001) of maximal torque. However, no difference between the vasti muscles were detected in both exercises. The estimates of synaptic input to the muscles confirmed these results. In conclusion, the estimated synaptic input received by VM and VL was similar within and across exercises. However, both muscles had higher firing rates and estimated synaptic input at the highest torque levels during knee extension. Taken together, the results show that knee-extension is more suitable than leg-press exercise at increasing the concurrent activation of the vasti muscles. NEW &amp; NOTEWORTHY There is a significant debate on whether open kinetic chain, single-joint knee extension exercise can influence the individual and combined activity of the vasti muscles compared with closed kinetic chain, multijoint leg press exercise. Here we show that attempting to change the contribution of either the vastus medialis or vastus lateralis via different forms of exercise does not seem to be a viable strategy. However, the adoption of open kinetic chain knee extension induces greater discharge rate and estimated synaptic input to both vasti muscles compared with the leg press.</p

Italian student-athletes only need a more effective daily schedule to support their dual career

Purpose: The present study aimed to investigate dual-career issues of Italian student-athletes according to gender, age, type of sport, competition level, university path, and year of attendance variables to highlight their main problems and solutions. Methods: An ad hoc 24-item questionnaire was administered to 711 academic Italian student-athletes (Mean age = 23; SD = 4&nbsp;years). A multivariate analysis was applied for data related to the first 21 (section A), whereas answers from the last 3 items (section B) were only described.Results: For section A items, two factors (factor 2: items 5, 7, 8, 14; Cronbach alpha = 0.728; factor 5: items 10, 11; Cronbach alpha = 0.78) related to sport participation and education for future job emerged. For both factors, effects emerged between \u201cyear of attendance\u201d subcategories (i.e., lower values for \u201cout of course\u201d subgroup), whereas only for factor 5, differences emerged in terms of age (i.e., higher values for younger than older subgroup). For section B, most student-athletes declared to wish schedules of lessons and exams (e.g., higher number of sessions; oral online interrogations) for better combining sport and academic requirements.Conclusion: The present study represents a further step to better understand the Italian student-athletes\u2019 daily and weekly limitations and wished solutions related to the combination of sport and academic tasks. Institutional bodies should consider the present findings in case of future policies in supporting dual career