Spatial frequency maps for haplogroups with frequencies above 3%, their Y-STR based phylogenetic networks in Corsican populations (Blue: North, Green: West, Orange: South, Black: Center and Purple: East) and their TMRCA (in years, +/- SE).

<p>Spatial frequency maps for haplogroups with frequencies above 3%, their Y-STR based phylogenetic networks in Corsican populations (Blue: North, Green: West, Orange: South, Black: Center and Purple: East) and their TMRCA (in years, +/- SE).</p

Description of the 18 Corsican, 1 Provençal and 3 Tuscan populations under study.

<p>Description of the 18 Corsican, 1 Provençal and 3 Tuscan populations under study.</p

A, Event free survival from major cardiovascular events in patients on basis of leukocyte telomere length at enrollment measured as t/s.

<p>B, Event free survival from major cardiovascular events in patients on basis of leukocyte telomere length at enrollment measured as t/s normalized.</p

Wilcoxon sum rank test on leukocyte telomere length presented t/s ratio normalized and cardiovascular risk factors of cases (n = 199).

<p>Data are presented as means and standard deviation. LTL, leukocyte telomere length; CAD, coronary artery disease.</p

Wilcoxon sum rank test on leukocyte telomere length presented t/s ratio normalized and cardiovascular risk factors of controls (n = 190).

<p>Data are presented as means and standard deviation. LTL, leukocyte telomere length; CAD, coronary artery disease.</p

F_st values (in bold) and genomic control inflation factor (λ_GC) (<i>in italics</i>) between Sardinian linguistic macro-areas.

<p>F_st values (in bold) and genomic control inflation factor (λ_GC) (<i>in italics</i>) between Sardinian linguistic macro-areas.</p

Nine genomic regions showing signals of positive selection in the Sardinian's genome ordered by |iHS|.

<p>Column headers: Position on NCBI36/hg18 of region showing evidence for selection; Size in Kb of the genomic region; nSNP |iHS|>4 indicates the number of SNPs with an absolute |iHS| higher than 4 in each region; nSNP is the number of SNPs in each region; Max iHS is the highest value of each region; Max iHS SNP is the polymorphism with the highest value for each region; P-values: nominal p-values; Empirical p-values: after permutation-based multiple testing corrections; Genes: the genes within the region. When, in the genomic region, there are more than 4 genes, only the first 4 are indicated.</p

ADMIXTURE software results for K = 2–4.

<p>Ancestry for each individual inferred using ADMIXTURE software.</p

SNP-Based Principal Component Analysis of 1,077 individuals from Sardinia.

<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0091237#pone-0091237-g002" target="_blank">Figure 2</a> A) division accounting linguistic macro-areas. Key of the colors: red: <i>Campidanese</i>; green: <i>Alghero</i>; deep blue: <i>Gallurese</i>; light blue: <i>Logudorese</i>; yellow: <i>Sassarese</i>; purple: <i>Nuorese</i>. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0091237#pone-0091237-g002" target="_blank">Figure 2</a> B) division accounting geographical areas. Key of the colors: green: <i>Southern Sardinia</i>; grey: <i>Central Sardinia</i>; yellow: <i>Northern Sardinia</i>.</p

Map of Mediterranean basin showing the localization of Sardinia and Sardinian linguistic domains.

<p>A) Map of the Mediterranean basin showing the geographic position of Sardinia. B) The Sardinian linguistic domains: 1 = <i>Gallurese</i> (77 individuals); 2 = <i>Nuorese</i> (88); 3 = <i>Logudorese</i> (385); 4 = <i>Sassarese</i> (342); 5 = <i>Alghero</i> (87); 6 = <i>Campidanese</i> (98).</p