Changes in pH and bicarbonate during isohydric and standard dialysis.

<p>Changes in pH and bicarbonate during isohydric and standard dialysis.</p

Changes in free fraction.

<p>Solute concentration and plasma clearance during isohydric and standard dialysis.</p

Proportion of variation accounted for by mixed models predicting free concentration from either pH or total concentration.

<p>Proportion of variation accounted for by mixed models predicting free concentration from either pH or total concentration.</p

Changes in pH and bicarbonate concentration during standard and isohydric dialysis.

<p>Individual lines are actual subject data, heavy lines are adjusted means from mixed model. The black vertical line represents the time during isohydric dialysis at which the bicarbonate buffer concentration was changed.</p

Changes in free fraction during isohydric and standard dialyses.

<p>Heavy lines connect fitted means from the mixed model analyses. Colored lines represent individual patient data.</p

Clinical characteristics of subjects.

<p>Clinical characteristics of subjects.</p

Changes in total solute concentration during isohydric and standard dialysis.

<p>Heavy lines represent fitted means from mixed model. Colored lines represent individual patient data.</p