Awareness, attitudes and knowledge about evidence based medicine among doctors in Gaza:A cross sectional survey

Evidence-based medicine (EBM) has emerged as a strategy to integrate research evidence within clinical decision-making. We have explored awareness, knowledge and attitudes about EBM among doctors in the Gaza Strip. In 2014, we conducted a cross-sectional survey among doctors working in health centres in Gaza, using a 20 item, web-based self-administered questionnaire. Approximately two thirds of the respondents welcomed EBM in principle, and believed that it could improve patient care. However, they had a relatively low level of knowledge about EBM. The main barriers to EBM mentioned by respondents were lack of knowledge needed to practise EBM [n= 47 (35%)]; negative attitude among senior colleagues [n= 34 (25%)]; lack of relevant resources [n= 31 (23%)]; work overload [n= 27 (20%)]; and lack of institutional support [n= 248 (18%)]. Thus, there are personal and organisational barriers to its practice that need to be addressed

A systematic review of educational interventions aiming to reduce prehospital delay in patients with acute coronary syndrome

Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Interventions aiming at reducing prehospital delay (PHD) in patients with acute coronary syndrome (ACS) have yielded inconsistent findings. Therefore, we aimed to systematically review studies which investigated the impact of educational interventions on reducing PHD in patients with ACS. We searched four electronic databases (Cumulative Index to Nursing and Allied Health Literature, MEDLINE, Embase, Cochrane) from inception throughout December 2016 for studies that reported the impact of either mass-media or personalised intervention on PHD. Reporting quality was assessed with the Template for Intervention Description and Replication checklist for interventional trials. Two reviewers screened 12 184 abstracts and performed full-text screening on 86 articles, leading to 34 articles which met our inclusion criteria. We found 18 educational interventions with a total of 180 914 participants (range: n=100-125 161) and a median of 1342 participants. Among these educational interventions, 13 campaigns employed a mass-media approach and five a personalised approach. Ten studies yielded no significant effects on the primary outcome while the remaining interventions reported a significant reduction with a decrease between 17 and 324 min (median reduction: 40 min, n=5). The success was partly driven by an increase in emergency medical services use. Two studies reported an increase in acute myocardial infarction knowledge. We observed no superiority of the personalised over the mass-media approach. Although methodological shortcomings and the heterogeneity of included interventions still do not allow definite recommendations for future campaigns, it becomes evident that either mass media or personalised interventions can be successful in reducing PHD, especially those who address behavioural consequences and psychological barriers (eg, denial) and provide practical action plan considerations as part of their campaign messages. CRD42017055684 (PROSPERO registration number)

Patient preferences for cardiovascular preventive medication:A systematic review

Objective To systematically review current evidence regarding the minimum acceptable risk reduction of a cardiovascular event that patients feel would justify daily intake of a preventive medication. Methods We used the Web of Science to track the forward and backward citations of a set of five key articles until 15 November 2016. Studies were eligible if they quantitatively assessed the minimum acceptable benefit - in absolute values - of a cardiovascular disease preventive medication among a sample of the general population and required participants to choose if they would consider taking the medication. Results Of 341 studies screened, we included 22, involving a total of 17 751 participants: 6 studied prolongation of life (POL), 12 studied absolute risk reduction (ARR) and 14 studied number needed to treat (NNT) as measures of risk reduction communicated to the patients. In studies framed using POL, 39%-54% (average: 48%) of participants would consider taking a medication if it prolonged life b