The Important Role of Optometrist and Qualified Nursing in Primary Healthcare for Eye Care

The use of evidence-based practice is essential for delivering high-quality care, ensuring patient satisfaction, and making efficient use of limited healthcare resources. Nevertheless, there have been reports of inconsistency in the administration of evidence-based eye care. To enhance our comprehension of the obstacles and enablers to delivering optometric care, it is necessary to recognize the significant role that optometrists play in providing primary eye care. This narrative study sought to identify the provision of eye care services by optometrists and measures that could enhance the delivery of eye care in primary care settings, alongside certified nursing. In the field of optometry, similar to other healthcare professions like nursing, there has been a broadening of the optometrist\u27s responsibilities in primary eye care. This includes taking on tasks such as prescription medication, which was previously done by general practitioners. Within the field of optometry, this expanded responsibility entails overseeing eye diseases that do not necessitate treatment or monitoring in secondary healthcare settings, which were historically referred to. Nevertheless, any expanded responsibility necessitates educational assistance

Association between the expression of toll-like receptors, cytokines, and homeostatic chemokines in SARS-CoV-2 infection and COVID-19 severity

The recent identification of the involvement of the immune system response in the severity and mortality of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection highlights the importance of cytokines and chemokines as important factors in the clinical outcomes of COVID-19. However, the impact and roles of the BAFF/APRIL cytokine system, homeostatic chemokines (CXCL12, CXCL13, CCL19, and CCL21), as well as Toll-like receptor (TLR)-3/4 in COVID-19, have not been investigated. We sought to assess the expression levels and roles of TLR3/4, BAFF, APRIL, IFN-β, homeostatic chemokines (CXCL12, CXCL13, CCL19, and CCL21), SARS-CoV-2 IgG and IgM antibodies in patients with critical (ICU) and non-ICU (mild) COVID-19 and their association with mortality and disease severity. Significant high levels of TLR-4 mRNA, IFN-β, APRIL, CXCL13, and IgM and IgG antibodies were observed in ICU patients with severe COVID-19 compared to non-ICU COVID-19 patients and healthy controls. On the other hand, BAFF and CCL21 expression were significantly upregulated in non-ICU patients with COVID-19 compared with that in critical COVID-19 patients. The two groups did not differ in TLR-3, CXCL12, and CCL19 levels. Our findings show high expression levels of some inflammatory chemokines in ICU patients with COVID-19. These findings highlight the potential utility of chemokine antagonists as an immune-based treatment for the severe form of COVID-19. We also believe that selective targeting of TLR/spike protein interactions might lead to the development of a new COVID-19 therapy