In-vitro Relationship between Protein-binding and Free Drug Concentrations of a Water-soluble Selective Beta-adrenoreceptor Antagonist (Atenolol) and Its Interaction with Arsenic

The degree of binding of a drug to plasma proteins has a marked effect on its distribution, elimination, and pharmacological effect since only the unbound fraction is available for distribution into extra-vascular space. The protein-binding of atenolol was measured by equilibrium dialysis in the bovine serum albumin (BSA). Free atenolol concentration was increased due to addition of arsenic which reduced the binding of the compounds to BSA. During concurrent administration, arsenic displaced atenolol from its high-affinity binding Site I, and free concentration of atenolol increased from 4.286±0.629% and 5.953±0.605% to 82.153±1.924% and 85.486±1.158% in absence and presence of Site I probe respectively. Thus, it can be suggested that arsenic displaced atenolol from its binding site resulting in an increase of the free atenolol concentration in plasma

Assessment of impact of ten days fishing ban in the major spawning grounds of hilsa (Tenualosa ilisha, Fisher and Bianchi, 1984)

A study was undertaken to find out the impact of ten days fishing ban in the major spawning grounds of hilsa during October to December. The study revealed a positive impact of fishing ban during spawning season on reproduction success of hilsa. Proportionate distribution of male and female hilsa also showed a significant level of distribution in and around the spawning grounds where the ratio was 35:65. Percent of oozing hilsa during fishing ban period in the spawning grounds was observed 1.61%. About 5% spent hilsa was observed in the fish landing centers and was compared with the data of Global Environment Facility (GEF) and Bangladesh Fisheries Research Institute (BFRI) studies and was found about 2.80-3.57 times higher than that of the findings of 2002 and 2003. Estimated egg production value showed about 46,800 Kg of eggs could have been produced that indicating a positive impact of 10 days fishing ban in spawning season. Abundance of higher percentages of gravid hilsa was found which were not available in the same quantity and condition in the non-fishing ban period. During the present investigation, fairly higher amount of spent hilsa and juveniles were also observed in the spawning grounds. Along with the jatka fry, spawn and fries of other fishes were also found in higher quantity than the previous years and thus it is assumed that fishing ban also might have positive impact on the successful breeding of other fishes. Overall, the fishing ban was found effective for successful breeding of hilsa

A practical biogas based energy neutral home system for rural communities of Bangladesh

Growing demand of energy consumption, subsequent increase in energy generation costs, and increased greenhouse gas(GHG) emissions, as well as global warming from the conventional energy sources, encourages interest worldwide to bring a higher percentage of renewable energy sources such as biogas into the energy mix to build a climate friendly environment for the future. Moreover, due to high investment and maintenance costs, governments are not providing enough support for grid extension and delivering electricity to remote locations or rural areas, in particular, in under-developing countries like Bangladesh. Therefore, this paper presents an Energy Neutral Home System (ENHS) that can meet all its energy requirements from low-cost, locally available, nonpolluting biogas generated from animal waste, in particular, chicken and cow manure. The proposed ENHS has been developed for rural community, typically an area of 200 families, and will not only provide cooking gas and sustainable and affordable power supply to the community with low emissions, but will also facilitate high quality fertilizer for agricultural purposes. In-depth analysis clearly demonstrates that the proposed ENHS not only offers electricity and cooking gas to the community with the lowest costs, but also reduces the energy crisis and GHG emissions and can play an active role in developing socio-economic infrastructure of rural communities in Bangladesh in many ways

Non-puddling practice for rice-based cropping system increases carbon sequestration in soil

In Indo-Gangetic Plains, intensive rice-based cropping systems with conventional crop establishment practices has been followed for many years. Contradictory results are reported about the effect of rice monoculture or rice-upland crop rotations on soil properties. While CA practices may sequester C into the soil organic C pool and improve soil health, in most cases, the practice of CA in rice-upland rotations is only partial; conservation tillage and residues retention are followed for upland crops only but not for rice. So, whatever benefits may accrue from CA practices followed for upland crops are lost by several wet tillage operations followed by puddling. In the EGP, rice-upland crop growers are now adopting CA increasingly, namely non-puddling of rice, in the intensive triple cropping systems (Alam et al. 2016; Haque et al. 2016). The incorporation of minimum tillage and retention of more residues in these systems of the EGP will change the dynamics of C in soil but nature of these changes has not been explored yet. The study was, therefore, conducted to determine the C cycling in soils of rice-upland triple cropping systems under CA practices

The potential of mixed culture of freshwater giant prawn Macrobrachium rosenbergii de Man and tiger shrimp Penaeus monodon Fab. at Khulna region, Bangladesh

The freshwater giant prawn (golda), Macrobrachium rosenbergii and tiger shrimp (bagda), Penaeus monodon were stocked together with or without fin fishes at different stocking rates in semi-saline waters at Khulna region and their growth, survival, yield and costreturn analysis were made. Survival rate of golda and bagda ranged from 23.0 to 36.8% and 8.2 to 24%, respectively. The both species were significantly affected by their own stocking density. The average final weight of golda and bagda ranged from 62.4 to 73.3 g and 32.0 to 66.4 g. The bivariate analysis of average final weight of both golda and bagda revealed that golda positively and bagda negatively influenced by the total stocking density. However, the results of the individual sizes of both golda and bagda showed an increase in the proportions of smaller animals and a decrease in the proportion of larger ones with increasing stocking rates. The harvesting weights of all animals in the experimental ghers were in marketable sizes although their prices varied with the individual size. The total production comprised of both golda and bagda ranged from 514.6 to 952.8 kg ha·1, over a culture period of 10 months. Return on investment ranged from 51.0 to 125.7%

Embryonic and larval development of Mystus gulio (Ham.)

Mystus gulio eggs are strongly adhesive and contain relatively small yolk (0.75-1.0 mm). The egg envelop is thick and transparent. First cleavage (two cells), four cells, eight cells, sixteen cells and multi cells stages were found 20, 25, 35-40, 60 and 70 minutes after fertilization, respectively. The morula stage was visualized within 1.5 h after fertilization. The heart beat visible and the circulatory system commenced after 16 h of fertilization. Embryos hatched 18-20h after activation of egg. The newly hatched larva measured 2.82±0.03 mm in length and 0.32±0.06 mg in weight. The yolk sac was fully absorbed by the third day though larvae commenced exogenous feeding even before completion of yolk absorption. A 5-day old post larva began wandering in search of food. Ten-day old post larvae endowed with eight branched rays in dorsal fin and seven in caudal fin. Fifteen-day old post larvae had the pectm:al spine become stout though the embryonic fin folds had to be disappeared. The length of fingerlings ranged from 25-30 mm after 30 days, and their external features were just like those of an adult except that they were not sexually matured

Screening of promising biofortified short duration lentil cultivars for conservation agriculture in North-west Bangladesh

In Bangladesh, lentil (Lens culinaris Medikus subsp.culinaris) production was 0.26 million tons from 0.20 million hectares (average yield 1.3 t ha-1) which is 29 % of the total national pulse production (AIS, 2016). Globally, it is cultivated as a rainfed crop on 3.85 million hectares (m ha) with a yield of only 1.1 t ha-1 (Erskine et al., 2011). In rice based cropping patterns, after harvesting of t.aman rice maximum land remains fallow for about 90 days until establishment of the boro rice. Presently, this rice land cannot be used to grow lentil since varieties have 110-115 days duration (AIS, 2017). Promising biofortified short duration (83-90 days) lentil varieties can play an important role to expand its cultivation through establishing lentil by relay sowing into t.aman rice and harvesting before boro rice. The relay cultivation method involves no tillage and residue retention, and establishes the lentil before t.aman rice is harvested. The selection of promising biofortified short duration lentil genotypes under relay cultivation method is therefore important to accommodate in fallow between t.aman and boro rice

Growth performance and morphological variations of local and Thai climbing perch (Anabas testudineus, Bloch)

Climbing perch locally known as koi (Anabas testudineus) is a popular food fish in our country. Thai climbing perch was introduced in Bangladesh from Thailand. To explore the variation in growth performance and orphological features of local and Thai climbing perch a study was undertaken. The highest gain in length, weight and SGR were found in Thai koi 12.23±0.38 cm, 55.83±0.53 g and 7.92±0.11 %/day respectively. Fourteen morphometric characters were studied where eleven (TL, SL, HL, HBD, LBD, DFL, PECFL, PELFL, AFL, UJL and LJL) showed significant difference (p<0.01) in Thai koi from the local ones. Of the meristic characters no. of dorsal fin rays (hard), anal fin rays (hard), caudal fin rays and scale along lateral line (upper and lower) as recorded from the Thai koi were significantly higher (p<0.01) than that of the local koi. The no. of dorsal fin rays (soft) in Thai koi were also significantly higher (p<0.05) from that of local koi. The number of vertebra were also variable in local and Thai climbing perch (25 in case of local koi and 26 in case of Thai koi). Hence, the results obtained form the present study satisfy the characteristics of A. testudineus which reveals that both the local and Thai koi belongs to the same species. Growth performance of Thai koi was better compared to local koi reared in same conditions

Polyculture of carps using over-wintered fingerlings under different stocking densities

An on-farm trial was undertaken in twelve earthen ponds (1200-1600 m') to evaluate the growth and production of over-wintered fingerlings of rohu (Labeo rohita), catla (Carla catla) and mrigal (Cirrhinus rnrigala) in polyculture at three stocking densities. The stocking densities were 2,250; 3,250 and 4,250 fish/ha in treatment-1, treatment-2 and treatment-3, respectively. Fish in all ponds were fed with rice bran and mustard oil cake at the ratio of 3:1. Fish production obtained in three treatments were 2325±74.75, 2620±49.66 and 2982±171.52 kg/ha. The results demonstrated higher mean growth in T-1 than in T-2 and T-3. However, the highest production as well as net benefit was obtained in treatment-3