Study the possibility of the effect of fluoxetine on the process of implantation of the blastocyst in the uterus of pregnant albino rats?

The current study dealt with knowing the effect of fluoxetine on the process of implantation of the blastocyst in the uterus of pregnant rats, which occurs in the rat on the sixth day of pregnancy because the implantation of the blastocyst is a very critical period of pregnancy. 26 females and male rats were used. Female rats were divided into two groups, the control group, and included 4 rats injected with the physiological solution inside the peritoneal cavity from day zero of pregnancy. The treatment group of 12 females was divided into two groups, the first included 4 females who were injected from day 0 of pregnancy with fluoxetine 20 mg/kg of body weight, and the second also included 4 females who were injected from day 0 of pregnancy with 40 mg/kg of body weight, and the third also included 4 females. From day 0 of pregnancy, she was injected with fluoxetine 60 mg/kg body weight. The histological technique was applied to uterine sections on the 7th day of pregnancy, and samples were stained with hematoxylin-eosin stain.&nbsp

Study of the effect of fluoxetine on liver enzymes in the blood serum of pregnant albino rats

The current study examined the effect of fluoxetine on liver enzymes in pregnant female rats. 42 rats, including ten males, were used for inoculation only, while the number of females was 32 rats. Female rats were divided into two groups, the control group consisted of 8 rats. The fluoxetine-treated group of 24 females was divided into three groups. The first group included 8 pregnant female rats injected with fluoxetine at a concentration of 20 mg/kg of body weight from day 0 of gestation until day 7 or 18, and the second group also included 8 pregnant females injected with fluoxetine at a concentration of 40 mg/kg. of body weight from day day 0 of gestation until day 7 or 18, and the third group included 8 pregnant females injected with fluoxetine at a concentration of 60 mg/kg of body weight from day 0 of gestation until day 7 or 18, blood samples were collected on the 7 or 18 days From pregnancy from all animal groups to measure the following parameters: ALT, alkaline phosphatase, ALP, and aspartate aminotransferase (AST).&nbsp