75 research outputs found

    Analysis of microstructure effects on edge crack of thin strip during cold rolling

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    Edge cracks in cold rolling of the thin strip affect the strip quality and productivity significantly. In this study, an experimental and mechanical investigation on microstructures has been carried out to study the edge crack formation during cold rolling of the thin strip. The effects of the feed material microstructures on the edge crack evolution were studied employing optical microscopy and scanning electron microscopy (SEM). Experimental observation indicates that fine grain occurs in hot-rolled microstructure and coarse grain is produced in ferritic rolled microstructure. Different grain sizes affect significantly the formation mechanics of the microcrack, crack initiation, and orientation of crack extension. The grain size and grain boundaries effects on crack retardation are discussed also during edge crack initiation. During the crack growth in coarse grain, most edge crack tips will blunt, which improves the crack toughness by causing less stress concentration. Overall, the fine microstructure shows a good crack initiation resistance, whereas the coarse microstructure has a better resistance to crack propagation. This research provides additional understanding of the mechanism of microstructure influence on edge crack evolution of cold strip rolling, which could be helpful for developing defect-free thin strip

    A systematic review of the incidence of schizophrenia: the distribution of rates and the influence of sex, urbanicity, migrant status and methodology

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    BACKGROUND: Understanding variations in the incidence of schizophrenia is a crucial step in unravelling the aetiology of this group of disorders. The aims of this review are to systematically identify studies related to the incidence of schizophrenia, to describe the key features of these studies, and to explore the distribution of rates derived from these studies. METHODS: Studies with original data related to the incidence of schizophrenia (published 1965–2001) were identified via searching electronic databases, reviewing citations and writing to authors. These studies were divided into core studies, migrant studies, cohort studies and studies based on Other Special Groups. Between- and within-study filters were applied in order to identify discrete rates. Cumulative plots of these rates were made and these distributions were compared when the underlying rates were sorted according to sex, urbanicity, migrant status and various methodological features. RESULTS: We identified 100 core studies, 24 migrant studies, 23 cohort studies and 14 studies based on Other Special Groups. These studies, which were drawn from 33 countries, generated a total of 1,458 rates. Based on discrete core data for persons (55 studies and 170 rates), the distribution of rates was asymmetric and had a median value (10%–90% quantile) of 15.2 (7.7–43.0) per 100,000. The distribution of rates was significantly higher in males compared to females; the male/female rate ratio median (10%–90% quantile) was 1.40 (0.9–2.4). Those studies conducted in urban versus mixed urban-rural catchment areas generated significantly higher rate distributions. The distribution of rates in migrants was significantly higher compared to native-born; the migrant/native-born rate ratio median (10%–90% quantile) was 4.6 (1.0–12.8). Apart from the finding that older studies reported higher rates, other study features were not associated with significantly different rate distributions (e.g. overall quality, methods related to case finding, diagnostic confirmation and criteria, the use of age-standardization and age range). CONCLUSIONS: There is a wealth of data available on the incidence of schizophrenia. The width and skew of the rate distribution, and the significant impact of sex, urbanicity and migrant status on these distributions, indicate substantial variations in the incidence of schizophrenia

    Prognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study.

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    Background: Acute illness, existing co-morbidities and surgical stress response can all contribute to postoperative acute kidney injury (AKI) in patients undergoing major gastrointestinal surgery. The aim of this study was prospectively to develop a pragmatic prognostic model to stratify patients according to risk of developing AKI after major gastrointestinal surgery. Methods: This prospective multicentre cohort study included consecutive adults undergoing elective or emergency gastrointestinal resection, liver resection or stoma reversal in 2-week blocks over a continuous 3-month period. The primary outcome was the rate of AKI within 7 days of surgery. Bootstrap stability was used to select clinically plausible risk factors into the model. Internal model validation was carried out by bootstrap validation. Results: A total of 4544 patients were included across 173 centres in the UK and Ireland. The overall rate of AKI was 14·2 per cent (646 of 4544) and the 30-day mortality rate was 1·8 per cent (84 of 4544). Stage 1 AKI was significantly associated with 30-day mortality (unadjusted odds ratio 7·61, 95 per cent c.i. 4·49 to 12·90; P < 0·001), with increasing odds of death with each AKI stage. Six variables were selected for inclusion in the prognostic model: age, sex, ASA grade, preoperative estimated glomerular filtration rate, planned open surgery and preoperative use of either an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker. Internal validation demonstrated good model discrimination (c-statistic 0·65). Discussion: Following major gastrointestinal surgery, AKI occurred in one in seven patients. This preoperative prognostic model identified patients at high risk of postoperative AKI. Validation in an independent data set is required to ensure generalizability

    Changes in the Risk of Schizophrenia in Scotland: Is There an Environmental Factor?

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    Various studies have suggested that there may be an environmental factor in schizophrenia acting before or at birth but with delayed effects. Evidence that the risk of developing schizophrenia varies randomly with the year of birth would help confirm the existence of such a factor. Data from the Scottish Health Service Information and Statistics Division, comprising all first admissions for ICD-9 schizophrenia in the years 1963–91, were used to estimate the lifetime risk of developing schizophrenia for each year of birth from 1900 to 1969. In the period after 1928 the lifetime risk steadily declined. The rate of decline was greater in females. The random fluctuations in the risks in females did not change systematically, but there was a significant decline in the variability of these fluctuations in males. These random fluctuations suggest a possible role for randomly varying environmental influences around the time of birth. Our findings suggest a possible diminution in the role of such environmental influences in schizophrenia among males in Scotland in the years 1929 to 1969

    Academic performance of fnal year medical students at kerbala medical college

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    Objective Assessment of fnal year students’ examination results in Kerbala Medical College in the academic years 2014–2015 and 2015–2016. Methods Students’ achievements in different parts of the fnal year examination in Kerbala Medical College for the academic years 2014–2015 and 2015–2016. Students’ scores in different parts of the theoretical and clinical examinations were analyzed to determine the effectiveness of the assessment process. In addition, students’ cumulative scores for the preceding 5 years were explored to determine the association with fnal year scores. The data were analyzed using the (SPSS) version 20 through different descriptive and analytic statistical tools using: percentages, means, standard deviations, internal reliability, confdence intervals, factor analysis, t-test, ANOVA test and correlation. Results The results of mean score (scored out of 10 for all scores) and standard deviation theoretical exam in medicine, surgery, gynecology and obstetrics and pediatrics were: 4.55 ± 1.14, 5.62 ± 1.12, 7.15 ± 0.78, 6.31 ± 1.14, respectively and no gender difference was observed. While the comparable results in 2016 were: 5.61 ± 0.92, 5.28 ± 1.08, 7.13 ± 0.92, 7.79 ± 1.22. Performance, objective structured clinical examination (OSCE) total score were (in the same order) for 2015: 6.30 ± 0.83, 6.66 ± 0.88, 7.02 ± 0.91, 7.81 ± 0.99. On comparison of 2015 and 2016 results, minor signifcant differences were found. A signifcant positive association was found between graduation score and previous year’s scores. Minor signifcant gender differences were observed in only few assessed parameters. Conclusion The present study aimed at a correct in depth analysis of the evaluation process and an examination of Kerbala Medical College graduates in two successive years. The results found were very helpful in pointing out the main shortcomings and strength in the examination stations

    Changes in the risk of Schizophrenia in Scotland: Is there an environmental factor

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    Various studies have suggested that there may be an environmental factor in schizophrenia acting before or at birth but with delayed effects. Evidence that the risk of developing schizophrenia varies randomly with the year of birth would help confirm the existence of such a factor. Data from the Scottish Health Service Information and Statistics Division, comprising all first admissions for ICD-9 schizophrenia in the years 1963–91, were used to estimate the lifetime risk of developing schizophrenia for each year of birth from 1900 to 1969. In the period after 1928 the lifetime risk steadily declined. The rate of decline was greater in females. The random fluctuations in the risks in females did not change systematically, but there was a significant decline in the variability of these fluctuations in males. These random fluctuations suggest a possible role for randomly varying environmental influences around the time of birth. Our findings suggest a possible diminution in the role of such environmental influences in schizophrenia among males in Scotland in the years 1929 to 1969

    EVALUATION OF FOLIAR SPRAY WITH EXTRACT OF MARINE ALGAE AND YEAST AND MOWING DATE ON GROWTH, YIELD, AND ACTIVE COMPONENTS OF WATERCRESS.

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    The experiment was implemented in the fields of the College of Agricultural Engineering Sciences / University of Baghdad during the agricultural season 2021-2022 as a factorial experiment (2 x 3 x 3) with within Randomized Complete Block Design using 3 replcates, The spraying with marine algae extract (0, 4, and 6ml.l-1) represented the first factor symbolized by K0, K1, and K2; the second factor involved spraying with the yeast extract (0, 2, and 4 mg.l-1) referred to as Y0, Y1, and Y2; while the third factor was mowing date as tow mows were applied with 15 days interval between them. The research was aimed to examine the effect of the three mentioned factors and their interaction on the vegetative growth and leaf biochemical traits of watercress plants. The research objectives Results showed a significant superiority of the interaction treatment Y2K2 in increasing number of leaves, leaf area, fresh weight, and dry weight in the second mow (62.80 leaves.plant-1, 131.77cm.plant-1, 265.30g, and 113.5g) as well as increasing the biochemical traits in leaves including the content of carbohydrates, protein, N, P, K, Glucosinolates, total Glucosinolates, total phenolic compounds, and total flavonoids in the second mow.                  

    Total hip replacement in sickle cell disease

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    Limbic dysfunction in schizophrenia and mania. A study using 18F-labelled fluorodeoxyglucose and positron emission tomography.

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    BACKGROUND: Diagnostic classes (derived from CATEGO) can be correlated with regional brain metabolism in patients with major psychiatric disorders. METHOD: Seventeen patients with schizophrenia, 15 with mania, 10 with depression and 10 healthy Volunteers were examined with positron emission tomography (PET) and 18F-labelled fluorodeoxyglucose, as a marker for glucose metabolism. The number of possible comparisons of regions of interest was reduced by principal-components analysis, and differences in factor scores were determined between diagnostic groups. RESULTS: Four independent factors, representing distributed brain systems, emerged: an anterior-posterior (1), a left-right temporal (2), a temporofrontal (3), and a mediofrontal (4) system, of which (1), (2) and (3) were abnormal in schizophrenia, (1) and (2) in mania, and (1) in depression. CONCLUSIONS: Abnormal patterns of metabolism could be detected, in decreasing order, in schizophrenia, mania and depression. Some of these abnormalities are likely to be due to medication, but others will be associated with structural or functional abnormalities of the frontolimbic system in the diagnostic groups
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