PHYTOCHEMICAL, ANTI-INFLAMMATORY, ANALGESIC, ANTIPYRETIC AND ACUTE TOXICITY OF PSIADIA PUNCTULATA GROWING IN YEMEN

Background: Psiadia punctulata growing in Yemen is used traditionally for different medicinal purpose, such as in casts of broken bones and for relief of pain, fever and abdominal pain. Objective: To determine the chemical composition and to assess the anti-inflammatory, analgesic, and antipyretic activity of P. punctulata leaf extracts. Method: Phytochemical screening of P. punctulata ethyl acetate and ethanol extracts were performed using chemical tests and thin layer chromatography. An acute oral toxicity study was conducted in rats by administering oral ethanol leaf extract of up to 5000 mg/kg. The anti-inflammatory activity of orally administered ethyl acetate and ethanol extracts (200, 400 mg/kg) and diclofenac (20 mg/kg) were evaluated using a formalin-induced inflammation rat model. The analgesic activity of orally administered ethyl acetate and ethanol leaf extracts (100, 200, 300mg/kg), compared to diclofenac (20 mg/kg) were evaluated by a formalin-based test as well. The antipyretic activity of oral ethyl acetate and ethanol extracts (400 mg/kg) versus paracetamol (150mg/kg) was assessed in Baker’s Yeast-induced pyrexia rats. Results: The phytochemical analyses indicated the presence of alkaloids, carbohydrates, steroids, phenolic compounds/tannins, phytosterols, saponins, gum and mucilage. The ethanol extract of the plant was apparently safe in rats at doses as high as 5000 mg/kg body weight. Time- and dose-dependent anti-inflammatory activity of the ethyl acetate and ethanol extracts (200 and 400 mg/kg) were clearly observed in rats. The results showed that both extracts exerted significant analgesic and antipyretic effects. Conclusion: Psiadia punctulata possess anti-inflammatory, analgesic and antipyretic activities with a wide safety margin.                        Peer Review History: Received: 22 September 2020; Revised: 7 October; Accepted: 26 October, Available online: 15 November 2020 Academic Editor: Rola Jadallah, Arab American University, Palestine, [email protected] UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file:                Reviewer's Comments: Average Peer review marks at initial stage: 6.5/10 Average Peer review marks at publication stage: 8.0/10 Reviewer(s) detail: Dr. Gehan Fawzy Abdel Raoof Kandeel, Pharmacognosy Department, National Research Centre, Dokki, 12622,  Giza, Egypt, [email protected] Ahmad Najib, Department of Pharmacognosy-Phytochemystry Universitas Muslim Indonesia-Indonesia, [email protected] Similar Articles: ESTIMATION OF ANTI-INFLAMMATORY ACTIVITY AS WELL AS APOPTOTIC ACTIVITY OF ETHANOLIC EXTRACTS OF CROCUS SATIVUS ANTI-INFLAMMATORY AND ANTI-OXIDANT ACTIVITIES OF METHANOL EXTRACT OF BAPHIA NITIDA PHYTOCHEMICAL SCREENING AND IN-VITRO ANTIOXIDANT AND ANTI-INFLAMMATORY POTENTIAL EVALUATIONS OF METHANOLIC EXTRACTS OF COCOS NUCIFERA (L.) LEAVES PHYTOCHEMICAL SCREENING AND THIN LAYER CHROMATOGRAPHIC OF PRUNUS DULCIS (ALMOND) MEDICINAL PLANT LEAVES USED IN FOLK MEDICINE FOR TREATMENT OF WOUNDS AND BURNS IN HUFASH DISTRICT AL MAHWEET GOVERNORATE–YEME

LEVEL OF LEAD IN THE BLOOD AMONG FUEL STATION EMPLOYEES AND ITS RELATIONSHIP TO IMPAIRED LIVER AND KIDNEY FUNCTIONS IN DAMASCUS; SYRIA: OCCUPATIONAL EXPOSURE TO LEAD

Objectives:  Chronic exposure to lead is known to cause adverse health effects. Workers at fuel stations are exposed to high concentrations of lead during filling cars and through Car’s emissions and being in contact with contaminated hands, food, water and clothing. This study was designed to find blood lead level and their adverse effects on kidney and liver function among fuel station workers. Methods:  Forty fuel station workers (exposed group) and thirty apparently healthy subjects (non-exposed group) in Damascus were randomly selected for the study. Blood lead levels were determined using Atomic absorption spectrometry after microwave-assisted acid digestion. Serum concentration of creatinine, uric acid and urea values were recorded to assess kidney function, whereas AST and ALT serum concentrations were used to evaluate liver function. Results:  The results showed a non-significant elevation of blood lead level in the exposed group (11.04 ± 10.36 µg/dl) compared  to the non- exposed group (8.1±2.97 µg/dl). Serum concentration of creatinine and uric acid were significantly elevated in the exposed group, but there was no change in AST and ALT serum levels. Conclusion:  It is concluded that blood lead levels of fuel station workers don’t exceed the threshold that may cause kidney or liver dysfunctions.                        Peer Review History: Received 25 March 2020; Revised 12 April; Accepted 3 May, Available online 15 May 2020 Academic Editor: Dr. Amany Mohamed Alboghdadly, Princess Nourah bint abdulrahman university, Riyadh, [email protected] UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file:                Reviewer's Comments: Average Peer review marks at initial stage: 5.0/10 Average Peer review marks at publication stage: 8.0/10 Reviewer(s) detail: Dr. Ali Abdullah Al-yahawi, Al-Razi university, Department of Pharmacy, Yemen, [email protected] Prof. Dr. Hassan A.H. Al-Shamahy, Sana'a University, Yemen, [email protected] Dr. Asia Selman Abdullah, Al-Razi university, Department of Pharmacy, Yemen, [email protected] Similar Articles: LEAD ACETATE: A DANGEROUS ENVIRONMENTAL TOXICANT THAT IS AMELIORATED BY THE AQUEOUS EXTRACT OF FICUS VOGELII (FV

ANTIDIABETIC AND ANTIHYPERLIPIDEMIC ACTIVITY OF DRACAENA CINNABARI BALF. RESIN ETHANOLIC EXTRACT OF SOQATRA ISLAND IN EXPERIMENTAL ANIMALS

Objective:  Dracaena cinnabari  balf is a species plant in Abalfurn 1984e de la p pharmaciegavaceae family. It is a tree endemic to the Island of Socotra, Yemen. It was used as a dye and medicine in Socotra  and the Mediterranean basin. Some researches demonstrated both hypoglycemic and hypolipidemic of its resin of Dracaena cochinchinensis, a traditional Chinese tree. Accordingly, this study aimed to evaluate the antidiabetic potential of the ethanolic extract of Dracanea cinnabari balf resin (DCBR), endemic in Socotra Island, in Alloxan induced diabetes, and evaluation of possible antihyperlipidemic activity of the same extract in high-cholesterol diet-induced hyperlipidemia in male albino rats. Methods: Experimental diabetes was induced in rats with intraperitoneal injection a single dose of Alloxan (150 mg/Kg). Hyperlipidemia was induced in rats by administration of 1% cholesterol in diet and 0.5 % Hydrogen Peroxide in drinking water for 14 days. Fasting blood glucose levels were measured at 1st day, 7th day and 14th day. Pancreas histopathology was done at the end. Estimation of serum lipid profile and liver   histopathology was done at the end of 14 day. The results were expressed as mean±SD and differences among the groups of animals were compared using one-way ANOVA. Results: Administration of ethanolic extract of resin of two doses (100 and 300mg\Kg) in alloxan induce diabetic rats resulted in a significant decrease in FBG levels with a recovery in destruction of pancreas cell compared with untreated group .Also the same doses of extract showed significant decrease in triglycerides, total cholesterol, low density lipoprotein, very low density lipoprotein and Atherogenic index in comparing with untreated group. Conclusion: From the results of present study we can conclude the ethanolic extract of Dracaena cinnabari Balf. have a hypoglycemic and hypolipidemic activity in experimental animals  , these activity are time and dose dependent.                               Peer Review History: Received 7 October 2018;   Revised 18 October; Accepted 1 November, Available online 15 November 2018 Academic Editor: Dr. Gehan Fawzy Abdel Raoof Kandeel, Pharmacognosy Department, National Research Centre, Dokki, 12622,  Giza, Egypt, [email protected]  UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file:        Reviewer's Comments: Average Peer review marks at initial stage: 5.5/10 Average Peer review marks at publication stage: 8.0/10 Reviewer(s) detail: Dr. Rana Ahmed MohamedEl-Saied El-Fitiany, Ahram Canadian University, Giza, Egypt, [email protected] Dr. Mohamed Derbali, Faculty of Pharmacy, Monastir, Tunisia, [email protected] Similar Articles: EVALUATION OF METHANOLIC EXTRACT OF EUPHORBIA NERIIFOLIA STEM BARK ON BLOOD SUGAR LEVELS, SERUM AND TISSUE LIPIDS IN A PRECLINICAL MODEL HYPOGLYCEMIC AND LIPID LOWERING EFFECT OF AQUEOUS FRESH LEAF EXTRACT OF CHROMOLAENA ODORATA (LINN) IN ALBINO WISTAR RATS FED DIFFERENT CONCENTRATIONS OF CHOLESTEROL ENRICHED DIE

ALOE IRAFENSIS AN ENDEMIC PLANT OF YEMEN: PHYTOCHEMICAL SCREENING, ANTIBACTERIAL, ANTIOXIDANT, AND WOUND-HEALING ACTIVITIES

Objectives: The objectives of the study were to determine the phytochemical constituents and assess the antibacterial, antioxidant, and wound-healing properties of the methanol extracts of Aloe irafensis. Methods: Methanol extracts of A. irafensis’s latex, gel, and green skin were screened for their phytochemical constituents. All three extracts were investigated regarding their antibacterial potential using disc diffusion and microdilution assays, and their antioxidant activity using 2,2-diphenyl-1- picrylhydrazyl free-radical scavenging assay. Histopathological study of wound healing area was performed for the latex extract in male albino rats. Results: The methanol extracts of A. irafensis revealed the presence of carbohydrates, steroids, phenols, tannins, and anthrones. The latex extract showed greater inhibition zones against Staphylococcus aureus and Pseudomonas aeruginosa (24 and 17 mm, respectively) and minimum inhibitory concentration values of 1.25 and 2.50 mg/ml, respectively. The latex extract showed the highest antioxidant activity (IC50 of 65.54 μg/ml), followed by green skin (IC50 of 89.48 μg/ml). The latex extract significantly accelerated the rate of wound healing in rats (p<0.01), compared to fucidin ointment, a reference control. Histological findings showed remarkably less scar width at wound closure site in the latex extract-treated wounds. Granulation tissue contained fewer inflammatory cells and more fibroblasts in wounds treated with the latex extract compared to those treated with the vehicle. Conclusion: A. irafensis latex extract is a potential source of bioactive compounds that can be used as antioxidant, antibacterial, and wound healing agents

Statistical Evaluation and Trend Analysis of ANN Based Satellite Products (PERSIANN) for the Kelani River Basin, Sri Lanka

Satellite-based precipitation products, (SbPPs) have piqued the interest of a number of researchers as a reliable replacement for observed rainfall data which often have limited time spans and missing days. The SbPPs possess certain uncertainties, thus, they cannot be directly used without comparing against observed rainfall data prior to use. The Kelani river basin is Sri Lanka’s fourth longest river and the main source of water for almost 5 million people. Therefore, this research study aims to identify the potential of using SbPPs as a different method to measure rain besides using a rain gauge. Furthermore, the aim of the work is to examine the trends in precipitation products in the Kelani river basin. Three SbPPs, precipitation estimation using remotely sensed information using artificial neural networks (PERSIANN), PERSIANN-cloud classification system (CCS), and PERSIANN-climate data record (CDR) and ground observed rain gauge daily rainfall data at nine locations were used for the analysis. Four continuous evaluation indices, namely, root mean square error (RMSE), (percent bias) PBias, correlation coefficient (CC), and Nash‒Sutcliffe efficiency (NSE) were used to determine the accuracy by comparing against observed rainfall data. Four categorical indices including probability of detection (POD), false alarm ratio (FAR), critical success index (CSI), and proportional constant (PC) were used to evaluate the rainfall detection capability of SbPPs. Mann‒Kendall test and Sen’s slope estimator were used to identifying whether a trend was present while the magnitudes of these were calculated by Sen’s slope. PERSIANN-CDR performed well by showing better performance in both POD and CSI. When compared to observed rainfall data, the PERSIANN product had the lowest RMSE value, while all products indicated underestimations. The CC and NSE of all three products with observed rainfall data were also low. Mixed results were obtained for the trend analysis as well. The overall results showed that all three products are not a better choice for the chosen study area.publishedVersio

PHYTOCHEMICAL, ANTI-INFLAMMATORY, ANTIOXIDANT, CYTOTOXIC AND ANTIBACTERIAL STUDY OF CAPPARIS CARTILAGINEA DECNEFROM YEMEN

Objective: To investigate phytochemicals and biological activities of Capparis cartilaginea extracts.Methods: The methanolic extracts of leaves, stem and twigs of C. cartilaginea were screened for their phytochemicals. The essential oil of the leaves was hydrodistilled by a Clevenger apparatus and analyzed by gas chromatography-mass spectrometry (GC-MS). The leaves extract of C. cartilaginea was evaluated for its anti-inflammatory effect, using formalin-induced paw edema. The leaves, stem and twig extracts were assessed for their antioxidant activity, using free radical scavenging assay, cytotoxic activity, using 3-[4,5-dimethylthiazole-2-yl]-2,5-diphenyltetrazolium bromide (MTT) assay and antibacterial activity, using the microdilution method.Results: All extracts of C. cartilaginea contained alkaloids, carbohydrates, protein, coumarin, phytosterols, bitter principles, phenols and tannins. The essential oil of the leaves was mainly composed of isopropyl isothiocyanate (69.4%), butane,1-isothiocyanate (26.97%) and isobutyl isothiocyanate (3.26%). The leaves extract at doses of 200 and 400 mg/kg, significantly inhibited paw edema at the 3rd h (49.1%, 54.0%, respectively) and this effect was comparable to that of diclofenac (58.87%). The leaves extract showed the highest antioxidant activity with IC50 value of 91.71 µg/ml. The twigs extract exhibited the highest cytotoxic activity against human lung carcinoma (A549) with IC50 of 57.5 µg/ml. The leaves and stem extracts exhibited antibacterial activity against Staphylococcus aureus with minimum inhibitory concentration (MIC) of 5.0 mg/ml. Conclusion: The leaves extract of C. cartilaginea is a potential source of bioactive compounds that could have a role in anti-inflammation. Twigs extract of the C. cartilaginea possesses a potential cytotoxic effect on human lung cell line

SEROPREVALENCE OF DENGUE FEVER VIRUS AMONG SUSPECTED PATIENTS IN TAIZ GOVERNORATE-YEMEN

Background: Dengue Fever virus (DENV) considers one of the most important mosquito-borne viral diseases in the world and it is endemic in more than 100 countries. Objective: This study aimed to determine the seroprevalence of DENV infection among suspected patients and to investigate some associated risk factors with dengue fever infection in Taiz governorate, Yemen. Methods: This study was cross-sectional, descriptive, and experimental, combining the use of a structured questionnaire and analysis of serum samples obtained from 300 suspected patients attending at many hospital and clinic centers in Taiz during the period from July to November 2016. The serum samples were tested for anti-dengue immunoglobulin (IgM) and (IgG) by Enzyme-linked Immunosorbent Assay (ELIZA). Results: Out of 300 suspected febrile cases, it was found that 49(16.3%), 68(22.7%), and 17(5.7%) cases were showed positive for the IgM, IgG, and both IgM and IgG antibodies, respectively, while 166 (55.3%) cases were negative. The incidence rate was more in males than in females. The most affected age group with dengue fever infection were (21–30) years. Dengue Fever was more frequent among patients coming from the urban area, having secondary school, and low-income status people. Also, there was statistical significant between DENV infections with a place of residencyand gender (P<0.05) and not-statistical significance between DENV infections and other factors (P>0.05). Conclusion: Taiz governorate become one of the endemic governorates in Yemen particularly the Taiz city which should be brought to the attention of public health authorities.                       Peer Review History: Received: 5 September 2020; Revised: 15 October; Accepted: 26 October, Available online: 15 November 2020 Academic Editor: Prof. Kumud Upadhyaya, Kumaon University, Nainital, UK, India, [email protected] UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file:                Reviewer's Comments: Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 7.0/10 Reviewer(s) detail: Dr. Rola Jadallah, Arab American University, Palestine, [email protected] Dr. Rawaa Souhil Al-Kayali, Aleppo University, Syria, [email protected] Similar Articles: QUALITY ASSESSMENT OF DIFFERENT BRANDS OF PARACETAMOL TABLETS IN YEMENI MARKE

PHYTOCHEMICAL SCREENING AND THIN LAYER CHROMATOGRAPHIC OF PRUNUS DULCIS (ALMOND) MEDICINAL PLANT LEAVES USED IN FOLK MEDICINE FOR TREATMENT OF WOUNDS AND BURNS IN HUFASH DISTRICT AL MAHWEET GOVERNORATE–YEMEN

Objective: Prunus dulcis (Almond) belongs to the family Rosaceae and is rich in polyphenols, including hydroxybenzoic acids and aldehydes, flavonol and flavanone aglycones, and glycosides. The objective of current study was phytochemical screening of chemical constituents of Prunus dulcis extract.   Methods: In this study methanolic and aqueous extracts of one plant namely Prunus dulcis were screened for the presence of phytochemical constituents and tested for their antimicrobial and antioxidant activity. The qualitative phytochemical analysis revealed the results showed presence of alkaloids, terpenoids, glycosides, resins, saponins, tannins, flavonoids, phenols, and amino acid were present in the methanol extract, with absence of glycosides, and amino acids in the aqueous extracts in leaves plant.   Results: TLC tests conducted revealed Rf values in the leaves for alkaloids, flavonoids, tannins, phenols and saponins(0.92-0.96-0.96-0.95-0.96) respectively. The antimicrobial activity extracts against four bacterial isolates Staphylococcus aureus, Escherichia coli , Pseudomonas aeruginosa and Klebsiella sp. and a single fungal isolate Candida albicans with concentrations (0.5 mg/ml, and 1,0 mg/ml) of the extract were added to the disc and respective solvent was used as negative control. The antioxidative activity of leaf was evaluated by using 1,1-  diphenyl-2 picrylhydrazyl (DPPH), the results showed are 85.5%, lowest from standard, ascorbic acid 87.5%.   Conclusion: The present study showed that prunus dulcis are rich sources of useful secondary metabolites, suitable for use for medicinal purpose like treat wounds and burns diseases.                                      Peer Review History: Received 18 March 2019;   Revised 20 April; Accepted 5 May, Available online 15 May 2019 Academic Editor: Dr. Marwa A. A. Fayed, University of Sadat City, Egypt, [email protected] Received file:                Reviewer's Comments: Average Peer review marks at initial stage: 5.5/10 Average Peer review marks at publication stage: 8.5/10 Reviewer(s) detail: Dr. Rana Ahmed MohamedEl-Saied El-Fitiany, Ahram Canadian University, Giza, Egypt, [email protected] Dr. Mohamed Said Fathy Al-Refaey, University of Sadat City, Menofia, Egypt, [email protected]  Similar Articles: PHYTOCHEMICAL SCREENING AND IN VITRO ANTIOXIDANT AND ANTI-DIABETIC POTENTIALS OF PERSEA AMERICANA MILL. (LAURACEAE) FRUIT EXTRACT PHYTOCHEMICAL SCREENING AND IN-VITRO ANTIOXIDANT AND ANTI-INFLAMMATORY POTENTIAL EVALUATIONS OF METHANOLIC EXTRACTS OF COCOS NUCIFERA (L.) LEAVE

ANTIMICROBIAL AND ANTIOXIDANT ACTIVITY OF PSIDIUM GUAJAVA. (GUAVA) MEDICINAL PLANT LEAVES USED IN FOLK MEDICINE FOR TREATMENT OF WOUNDS AND BURNS IN HUFASH DISTRICT AL MAHWEET GOVERNORATE–YEMEN

Objective: Psidium guajava (PG) belongs to the family Myrtaceae that is believed to have active components that help to treat conditions like malaria, gastroenteritis, vomiting, diarrhea, dysentery, wounds, ulcers, toothache, coughs, sore throat, inflamed gums, and a number of other condition. The objective of current study was phytochemical screening of chemical constituents of Psidium guajava extract.Methods: In this study methanolic and aqueous extracts of one plant namely Psidium guajava, were screened for the presence of phytochemical constituents and tested for their antimicrobial and antioxidant activity.Results: TLC tests conducted revealed Rf values in the leaves for alkaloids, Flavonoids, Tannins, Phenols and Saponins(0.96-0.97-0.99-0.97-0.99) respectively. The antimicrobial activity extracts against four bacterial isolates Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Klebsiella sp. and a single fungal isolate Candida albicans with concentrations (0.5 mg/ml, and 1,0 mg/ml) of the extract were added to the disc and respective solvent was used as negative control. The antioxidative activity of leaf was evaluated by using 1,1- diphenyl-2 picrylhydrazyl (DPPH), the results showed are 88.4%, highest from standard, ascorbic acid 87.5%.Conclusion: The qualitative phytochemical analysis revealed the results showed presence of alkaloids, terpenoids, glycosides, resins, saponins, tannins, flavonoids, phenols, and amino acid were present in the methanol extract, with absence of glycosides, and amino acids in the aqueous extracts in leaves plant.                               Peer Review History: Received 24 March 2019;   Revised 10 April; Accepted 20 April, Available online 15 May 2019 Academic Editor:  Dr. Iman Muhammad Higazy, National Research Center, Egypt, [email protected] UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file:                Reviewer's Comments: Average Peer review marks at initial stage: 5.5/10 Average Peer review marks at publication stage: 7.5/10 Reviewer(s) detail: Ahmad Najib, Universitas Muslim Indonesia, Makassar, Indonesia, [email protected] Dr. Md. Shahidul Islam, USTC, Chittagong, Bangladesh, [email protected] Similar Articles: PHYTOCHEMICAL ANALYSIS AND ANTIMICROBIAL ACTIVITY OF COLOCASIA ESCULENTA (TARO) MEDICINAL PLANT LEAVES USED IN FOLK MEDICINE FOR TREATMENT OF WOUNDS AND BURNS IN HUFASH DISTRICT AL MAHWEET GOVERNORATE–YEME