Trends and practices in the use of non-prescription drugs among university students in the United Arab Emirates

Background: A wide variety of medication, from vitamins to analgesics and anti-inflammatory drugs, can be purchased by users without a medical prescription. These are referred to as Oral Non-Prescription Drugs (ONPD). While this may empower patients to treat themselves, when used irrationally these medications can have a negative health impact. Previous research on higher education students, particularly healthcare students, has demonstrated that they might be a high-risk population for irrationally use of ONPD. In 2004, the World Health Organisation issued specific guidelines to address research in this area. However, recent investigations still indicate that irrational use of medication occurs among this population. Therefore, the current thesis will be guided by the WHO framework in an attempt to develop a strategy to address this problem. Aim: The aim of this thesis is to determine the prevalence of irrational use of medication sold without a prescription in UAE to university students and to identify the reasons for this behaviour. A secondary aim of this investigation is to develop, implement and evaluate the effectiveness of an educational intervention to improve knowledge and awareness of, as well as attitudes and practice towards, rational use of ONPD medication by university students in UAE. To reach the aims of the study, a health behavioural model was used together with qualitative and quantitative methods. Methodology Study One: The aim of this study was to determine the prevalence and risk factors of four types of irrational use (incautious use, inappropriate use, use of antibiotics without prescription and polypharmacy) of ONPD among undergraduate students in UAE. This study used a cross-sectional design employing a randomised sampling technique (n=2875). Statistical analysis was used to analyse this data. Results obtained from this study indicated that 85.9% of students used ONPD, with 38.6% using antibiotics without a prescription. Based on WHO risk assessment criteria, this behaviour was found to the most severe form of irrational use. Additional findings indicated that female participants were 34% less likely to be incautious users (OR =0.344, 95% CI: 0. 244-0.486, p≤0.001), which set males at a higher risk of engaging in this behaviour. Not verifying the expiration date also increased the likelihood of being an incautious user by as much as 51%. Seeking drug information from health care professionals was found to be a protective factor against incautious ONPD use (OR =0. 798, 95% CI: 0.540-0.967, p967, p≤0.05). At the same time, not seeking information on cautious use of ONPD either from medical books or the internet was associated with a higher risk of incautious use (OR = 1.914, 95% CI: 1.353-2.708, p≤0.001). Being a healthcare student significantly increased the odds of being an incautious user of ONPD (OR = 1.561, 95% CI: 1.103-2.208, p≤0.05). Using antibiotics without a prescription was reported among 35.9% of the sample, with no statistically significant difference being observed between healthcare and non-healthcare students. Study Two: Based on the WHO Severity Rating Matrix, the use of antibiotics without prescription was found to be the most significant risk for personal and population health. Therefore, the aim of this study was to further explore the reasons for use of antibiotics without prescription among healthcare university students. This study used a qualitative design employing an interview method and a purposive sample selection technique (n=15) which included only the population of students who used antibiotics without a prescription. Thematic analysis was used to analyse the data. Five main themes emerged from this study: knowledge, awareness, attitude, views, and perceptions, as well as possible strategies to decrease their misuse of antibiotics. Study Three: The aim of this study was to develop and test an intervention for reducing the use of antibiotics without prescription based on the findings of study 1 and 2. The intervention was carried out for 14 weeks. Each session was delivered on a weekly basis and comprised of a 15 minutes PowerPoint presentation followed by 10 minutes of discussion. A quasi-experimental design with purposive sampling was used in which participants (n=140) were assessed at baseline for knowledge, awareness, attitude, and practice of using antibiotics without prescription. Results obtained through comparing baseline measures with post-intervention measures demonstrated a statistically significant (p<0.05) improvement in reducing the use of antibiotic without prescription among the sample. Moderate improvements were also noted in knowledge, attitude, and awareness of antibiotic use. Conclusion: This thesis has demonstrated that the prevalence of ONPD is high among university students in the UAE. This is particularly significant as this increased prevalence occurs concomitantly with irrational use. The most significant risk was related to using antibiotics without prescription. Although the intervention to change this behaviour was successful, other issues such as access to health care and lack of time to see medical practitioners may still promote the use of antibiotics without prescription. Recommendations underlined in this investigation include educating pharmacists to provide information to ONPD buyers

Segmentation and measurement of lung pathological changes for COVID-19 diagnosis based on computed tomography

Coronavirus 2019 (COVID-19) spread internationally in early 2020, resulting from an existential health disaster. Automatic detecting of pulmonary infections based on computed tomography (CT) images has a huge potential for enhancing the traditional healthcare strategy for treating COVID-19. CT imaging is essential for diagnosis, the process of assessment, and the staging of COVID-19 infection. The detection in association with computed tomography faces many problems, including the high variability, and low density between the infection and normal tissues. Processing is used to solve a variety of diagnostic tasks, including highlighting and contrasting things of interest while taking color-coding into account. In addition, an evaluation is carried out using the relevant criteria for determining the alterations nature and improving a visibility of pathological changes and an accuracy of the X-ray diagnostic report. It is proposed that pre-processing methods for a series of dynamic images be used for these objectives. The lungs are segmented and parts of probable disease are identified using the wavelet transform and the Otsu threshold value. Delta maps and maps created with the Shearlet transform that have contrasting color coding are used to visualize and select features (markers). The efficiency of the suggested combination of approaches for investigating the variability of the internal geometric features (markers) of the object of interest in the photographs is demonstrated by analyzing the experimental and clinical material done in the work. The suggested system indicated that the total average coefficient obtained 97.64% regarding automatic and manual infection sectors, while the Jaccard similarity coefficient achieved 96.73% related to the segmentation of tumor and region infected by COVID-19

Phytoplankton primary production in southern Iraqi marshes after restoration

Primary productivity and chlorophyll-a were used in this study to monitor the restoration process of southern Iraqi marshes (Al-Hewaizeh, central marshes, and Al-Hammar). The phytoplankton primary productivity was based on oxygen light/dark bottle method. Two different depths samples were taken monthly from six studied marshes stations (two stations for each marsh) during November 2005 to October 2006, while chlorophyll-a samples taken from surface water. The phytoplankton primary productivity values ranged 9.38 – 249.79 mg C/m3.hr for all marshes, its values for surface water sample ranged 11.71 – 256.24 mg C/m3.hr, while for 1m depth ranged 9.38 – 142.5 mg C/m3.hr. Chlorophyll-a values ranged between (1.1 – 21.26) µg/l indicating high values of productivity in the studied marshes comparing with other aquatic Iraqi ecosystems. Also, dissolved oxygen and oxygen saturation rate were measured in this study

Study of some physicochemical properties and bioactivity of gum extracted from Linum usitatissimum

Gum was extracted from linseed (Linum usitissimum) in north of Iraq, which it annual growth plant. Organoleptic characterization of: color, odor, taste, fracture and texture. Physico-chemical properties were determined: pH, bulk density, tapped density, bulkiness, swelling index, ash values, carr's index, Hausner's ratio and angle of repose. Thin Layer Chromatography paper was used to monitor the extracted saccharides by comparing the spots with the of the standards and flow rate Rf calculated. The FT-IR spectrum of the product showed an absorption bands at 3666.29 cm-1(–OH), 2966.76 cm-1(C-H), 2640.44 cm-1 (C=C), 1826.62 (C=O), 1420.04 (C-H bend). Anti-microbial activity evaluated of the gum and observed that gum does not any significant antibacterial activity such as cell wall destruction

Self-medication with oral antibiotics among University students in United Arab Emirates

Purpose: To investigate the prevalence of antibiotic use without prescriptions and to identify factors associated with this behavior among university students using oral non-prescription drugs (ONPD). Methods: A cross-sectional study was conducted among the students of major universities in UAE. A multistage sampling technique was used in the present study. Results: Out of 2875 students, only 2355 (81.9 %) questionnaire were fully answered and included. Of 2355, more than half (1348; 57.2 %) of the participants reported using ONPD. More than one-third (484, 35.9 %) of 1348 participants used antibiotics without a prescription during the 90 days prior to the present study. Binary logistic regression identified nine statistically significant variables: nationality (OR = 0.471, 95 % CI: 0.326 - 0.681, p < 0.001); cost-influence behavior (OR = 1.716, 95 % CI: 1.175 - 2.508, p < 0.005); belief in ONPD effectiveness (OR = 0.332, 95 % CI: 0 .135 - 0.815, p < 0.05); year of study (OR = 0.310, 95 %, CI: 0.141 - 0.681, p < 0.004); medication knowledge (OR = 0.619, 95 % CI: 0.443 - 0.866, p < 0.005); self-care orientation (OR=1.878, 95 % CI: 1.304 - 2.706, p < 0.001); using ONPD helps to save money (OR=1.665, 95 % CI: 1.047-2.649, p<0.04); and urgency of use (OR = 1.644, 95 %, CI: 1.144 - 2.363, p < 0.007); as well as being healthcare students (OR = 1.465, 95 %, CI: 1.012 - 2.120, p < 0.05). Conclusion: There is a need for educational intervention to improve students’ knowledge, attitude, and awareness regarding the risk of using antibiotics without prescriptions

Seasonal time-series modeling and forecasting of monthly mean temperature for decision making in the Kurdistan Region of Iraq

A generalized structural time-series modeling framework was used to analyze the monthly records of mean temperature, one of the most important environmental parameters, using classical stochastic processes. In this article we are using the SARIMA Box–Jenkins model and obtain a medium-term (10 years) forecast of the mean temperature in Erbil. A prediction of the monthly mean temperature during the past 287 months ((Formula presented.)24 years) using the SARIMA(0,1,2)(0,1,1)12 model predicts that the average temperature in the governorate of Erbil, Iraq, will be stable for the next 10 years. The evaluation of prediction accuracy shows that our model performs equally well when applying it to different periods of time for which data is available. The method used here could easily be applied by the decision makers responsible for providing water and electricity in the Kurdistan Region

Iktikaf: penting dan perlu/ Al-Kubaisi

122 hal.; 19 cm