Modeling of Neuropathic Bladder Lesions Diagnosis Using Neural Network Algorithm.

The urinary bladder is probably the only visceral smooth-muscle organ that is under complete voluntary control from the cerebral cortex. Normal bladder function requires interaction of sensory and motor components of both the somatic and autonomic nervous system. Recent advances in the understanding of neural pathways and neurotransmitters have shown that most levels of the nervous system are involved in the regulation of voiding function. Therefore many neuralgic diseases causes changes in the bladder function [1]. In this paper, Number of patients selected from Ibn-Alkiff hospital (for treatment and rehabilitation of Spinal cord injuries), in Baghdad, who were referred to the urology department for complains of some urinary symptoms, and examined by cystometry in the urology out patient and/or inpatient department. These cases were selected randomly who already consult these departments and were followed up and managed by the expert urosurgeons. They were adults complaining of general neuropathic bladder disorder symptoms like frequency, urgency, dysuria, urinary incontinence and were diagnosed as having neuropathic bladder disease, whether: Upper motor neuropathic bladder lesions. Lower motor neuropathic bladder lesions. And finally they were examined by cystometry. The collections of data from patients were about: Accommodation (compliance). • Bladder capacity. • Contractility. • Sensation. • Voluntary control. These data with the final definition diagnosis about the neuropathic bladder lesion were processed to 3- layers Neural Network algorithm that was constructed in a matlab computer package. Consequently after all data processing, the neural network model was tested by its capability of processing an already diagnosed neuropathic bladder case and its accuracy in explaining the real neurological bladder behavior of that selected patien

Low temperature decreases bone mass in mice: Implications for humans

ObjectivesHumans exhibit significant ecogeographic variation in bone size and shape. However, it is unclear how significantly environmental temperature influences cortical and trabecular bone, making it difficult to recognize adaptation versus acclimatization in past populations. There is some evidence that cold‐induced bone loss results from sympathetic nervous system activation and can be reduced by nonshivering thermogenesis (NST) via uncoupling protein (UCP1) in brown adipose tissue (BAT). Here we test two hypotheses: (1) low temperature induces impaired cortical and trabecular bone acquisition and (2) UCP1, a marker of NST in BAT, increases in proportion to degree of low‐temperature exposure.MethodsWe housed wildtype C57BL/6J male mice in pairs at 26 °C (thermoneutrality), 22 °C (standard), and 20 °C (cool) from 3 weeks to 6 or 12 weeks of age with access to food and water ad libitum (N = 8/group).ResultsCool housed mice ate more but had lower body fat at 20 °C versus 26 °C. Mice at 20 °C had markedly lower distal femur trabecular bone volume fraction, thickness, and connectivity density and lower midshaft femur cortical bone area fraction versus mice at 26 °C (p < .05 for all). UCP1 expression in BAT was inversely related to temperature.DiscussionThese results support the hypothesis that low temperature was detrimental to bone mass acquisition. Nonshivering thermogenesis in brown adipose tissue increased in proportion to low‐temperature exposure but was insufficient to prevent bone loss. These data show that chronic exposure to low temperature impairs bone architecture, suggesting climate may contribute to phenotypic variation in humans and other hominins.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/146428/1/ajpa23684.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/146428/2/ajpa23684_am.pd

The Effect of Thickness on the Physical Properties of Fe2O3 Thin Films Prepared by DC Magnetron Sputtering

The objective of this study is to assess the influence of nano-particle Fe2O3 thin film thickness on some physical properties which were prepared by magnetron DC- sputtering on glass substrate at room temperature. The structure was tested with X-Ray diffraction and it was to be amorphous and to become single crystal with recognized peak in (003) after annealing at temperature 500oC. The physical properties as a function of deposition parameters and then film thickness were studied. The optical properties such as absorbance, energy gap and some optical constants are measured and found that of about (3eV) energy gap

The short term effects of a supra-lethal dose of irradiation and changes in the environmental temperature on the growth of tail bones of the mouse.

The growth and histological features of the tail vertebrae of young mice (31 day old) were observed for 48 h after transference from a cold (8 degrees) to a hot (33 degrees) environment. Some mice received a massive (5000 rad) dose of X-ray to the tail. Less than 2 h after housing the animals in the heat there was a period of very rapid growth lasting 12 h after which time growth slowed but was still much greater than the animals in the cold. Animals whose tails were irradiated (and also put in the heat) showed the same rapid growth for 12 h but after this growth ceased. Evidence is provided which shows that the initial rapid growth in the heat is due to an abnormal increase in the linear dimensions of the hypertrophic cells of the growth plate. This is most marked in the hot-irradiated animals