Assessment of noggin level in pulmonary arterial hypertension patients

Noggin (NOG) is a protein that is involved in the development of many body tissues, including nerve tissue, muscles, and bones. The NOG protein plays a role in germ layer-specific derivation of specialized cells. Via NOG, the formation of neural tissues, the notochord, hair follicles, and eye structures arise from the ectoderm germ layer, while noggin activity in the mesoderm gives way to the formation of cartilage, bone and muscle growth. In the endoderm, NOG is involved in the development of the lungs

Presepsin level in children infected with community-acquired pneumonia

Objective: To investigate the expression of Presepsin (P-SEP) in children infected with Community-acquired pneumonia and its correlation with total white blood cell count (WBC), gender and age. The current study included sixty (60) patient suffering from acquired community pneumonia  aged  range between one year to larger than 6 years, gander (30) female and (30) male Children in  Al Zahara Teaching Hospitals in Najaf Provenance , during November 2020 – March 2021. The (30) control Child without suffering any of symptoms or criteria of acquired community pneumonia our results show significant elevation (p<0.05) in Total Leukocytes count and presepsin in pneumonia patient group in comparison with control group and non-significant (p>0.05) different in presepsin level between female and male pneumonia child patients. The results also indicate significant elevation (p <0.05) in serum presepsin level of pneumonia child patient among the age (1-3 y) when compare with among the ages (4-6 y) and (>6y) of pneumonia child patient .And there is no significant (p>0.05) different in presepsin between the ages (4-6y) when compare with ages (>6y)

Study of Procalcitonin and neutrophil/ lymphocyte count ratio in children infected with Community-acquired pneumonia

Objective: Investigate the expression of procalcitonin (PCT) in children infected with Community-acquired pneumonia (CAP), and its correlation to the number of white blood cells (WBC), and neutrophil/ lymphocyte count ratio (NLR). The current study included sixty (60) patient suffering from acquired community pneumonia  aged  range between one year to larger than 6 years, gander (30) female and (30) male Childs in  Al Zahara Teaching Hospitals in Najaf Provenance , during November 2020 – M arch 2021. The (30) control Child without suffering any of symptoms or criteria of acquired community pneumonia our results show a significant increment (p<0.05) in total count of leukocytes, Neutrophils, N/L ratio, lymphocytes (10⁹/L) and PCT level in Pneumonia patients group compared with control group respectively, and non-significant (p>0.05) different in biomarker procalcitonin level between female and male pneumonia child patients. Serum procalcitonin level demonstrate a statistically significant elevation (p <0.05) in the pneumonia child patient among the age (1-3 y) when compare with other ages