Comparison of Liquefaction Potential of Loess in China, USA, and Russia

Loess is extensively distributed in many parts of the world, including China, the United State and Russia. Based on experimental study of loess obtained from the three countries, the liquefaction potential of loess are investigated. It is found though loess in the three country all have liquefaction potential, their peak ground acceleration of triggering liquefaction and their behavior during liquefaction vary significantly. Further study of microstructure of loess reveals that the microstructure of the loess in the three countries differs each other in many ways. This factor, combined with the different of gradation, physical index and formation materials, accounts for the different liquefaction behavior of loess in the three countries. Under no circumstance, however, should the liquefaction problem of loess be ignored for its dangerous effects caused by great amount of residual strain during liquefaction

Regulatory and Legal Bases of Extracurricular Activities in the SPO System

В данной статье представлены нормативно-правовые аспекты внеурочной деятельности в организациях среднего-профессионального образования, а также освещены проблемы, касающиеся реализаций внеурочной деятельности в системе СПО.This article presents the regulatory and legal aspects of extracurricular activities in organizations of secondary vocational education, as well as highlights the problems related to the implementation of extracurricular activities in the SPO system

Nanodispersed Ni-catalysts with Additives in Partial Oxidation of Methane

Catalytic activity of Ni-Zn-surface-skeletal catalysts modi ed by Rh, Au, Ti, Mo and W in the reaction of methane partial oxidation has been studied. In uence of catalysts of conditions preparation on its catalytic activity was researched. It was shown that introduction of additives in Ni-Zn catalysts promote to increasing of activity in the process of methane partial oxidation to synthesis-gas and thermostability of skeletal Nicatalysts thanks to the change of its faseous composition and the predominance of reduced form of Ni in catalysts structure

Criteria of Health and Healthy Lifestyle of Modern Students of Professional Educational Organizations

В статье говориться о значимости критериев здоровья у современных студентов обучающихся в профессиональных образовательных организациях, также отражены проблемы существующих критериев здорового образа жизни студентов

Condition of the Mechanoactivated Calcium Chloride Solution and its Influence on Structural and Mechanical Characteristics of Cement Stone

Using the method of dynamic light scattering we investigated the influence of the rotor and pulse impact on a dimensional change of particles in calcium chloride hydrosol used as texturing additives in concrete mixing. The mechanism of the strengthening action of the additive is shown by the results of an assessment of the parameters of the pore structure of the cement stone which is carried out by the method of the low-temperature adsorption and desorption of nitrogen vapors. With the use of the method of the low-temperature adsorption desorption of nitrogen for the analysis of porosity of the experimental exemplars of the cement stone received with the use of the mechanically activated CaCl2 solution, decrease in the area of a specific surface area in 1.7 … 2.1 times and the volume of pore spaces by 1.6 times that is caused by preferred decrease of the maintenance with the diameter over 6 nanometers and decrease in an upper bound of pore size from 160 to 90 nanometers is shown

Social Networks as a Way to Promote a Healthy Lifestyle and Physical Activity of Modern Youth

Современная молодежь довольна сильно подвержена влиянию моды и иных тенденций, которые можно наблюдать в различных социальных сетях, именно поэтому данное поле деятельности при определенных условиях поможет в популяризации здорового образа жизни и различных видов двигательной активности

Justification of using internet marketing tools for promotion on the medical services market

The article presents the methods of using marketing tools to increase profit of the medical company. The relevance of the research topic is due to the fact that at most clinics there is an acute problem of promoting the services provided. The Internet is characterized by a constant increase in the audience, which makes this market global. Therefore, an increasing number of medical centers are spending their funds for analysis of Internet marketing in order to reach more potential customers and significantly increase profits in the face of a reduction in the budget for promoting their servicesВ статье рассмотрены методы применения различных средств инструмент маркетинга для увеличения прибыли медицинской организации. Актуальность темы исследования обусловлена тем, что в большинстве клиник остро стоит проблема продвижения оказываемых услуг. Сеть Интернет характеризуется постоянным увеличением аудитории, что делает данный рынок глобальным. В этой связи все большее количество медицинских центров расходуют свои средства на изучение интернет - маркетинга с целью большего охвата потенциальных клиентов и значительного увеличения прибыли в условиях сокращения бюджета на продвижение своих услуг

Diagnosis of spondyloarthritis: should we need new criteria?

A large number of classification criteria for spondyloarthritis (SpA) are simultaneously used in modern rheumatology in the almost complete absence of diagnostic criteria. This poses a number of problems, among which there are two most important ones: 1) the frequent use of classification criteria to make a diagnosis in real clinical practice; 2) the possibility of stating different nosological entities of SpA in one patient in the presence of the same clinical picture.Objective: to investigate the specific features of the diagnosis of SpA and the use of its classification criteria in clinical practice.Subjects and methods. The investigation enrolled 119 patients with the established diagnosis of ankylosing spondylitis (AS), psoriatic arthritis (PsA), undifferentiated axial or peripheral SpA. Whether their clinical picture complied with the modified New York criteria, the European Spondyloarthropathy Study Group (ESSG) criteria, the Amor criteria, and the Assessment of Spondyloarthritis International Society (ASAS) classification criteria for axial and peripheral SpA and whether the Russian version of the modified New York criteria complied with the Classification criteria of Psoriatic ARthritis (CASPAR) were determined in the patients.Results. Sixty-three patients diagnosed with AS (M45), 44 with PsA (M07.0-07.3), 8 with undifferentiated SpA (M46.9), and 4 with nonradiographic axial SpA (M46.8) were followed up by attending physicians. The latter diagnosed AS in 10 patients who met the ASAS criteria for axial PsA but not the modified New York criteria. Twenty-one patients diagnosed as having PsA simultaneously met both the CASPAR criteria and the modified New York criteria, which could establish the diagnosis of AS in these cases. Eighty-one (68.0%) out of the 119 patients met the Amor criteria; 98 (82.3%) patients, the ESSG criteria; 91 (76.5%), the ASAS criteria for axial SpA; 18 (15.1%), the ASAS criteria for peripheral SpA; 76 (63.8%), the modified New York criteria; 88 (73.9%), the Russian version of the modified New York criteria; 42 (32.3%), the CASPAR criteria. No intersection of criteria was observed in only 5 patients; 113 (94.9%) patients met ≥2 criteria; 96 (80.7%), ≥3 criteria; 81 (68.1%), ≥4 criteria; 66 (55.5%), simultaneously ≥5 criteria; and 18 (15.1%), simultaneously 6 criteria.Conclusion. Most patients with SpA meet ≥2 classification criteria, which gives the chance to state ≥2 nosological entities in the same patient. This demonstrates the elaboration of diagnostic criteria that can make a clear distinction between different forms of SpA in clinical practice

Mononuclear subsets and cytokine profile of venous and capillary blood in patients with psoriasis and healthy people

Psoriasis is considered an autoimmune disease with a predominantly cellular mechanism for the development of disorder. Studies in immune pathogenesis of psoriasis were performed either in animal model, which is not just similar to humans, or the data were obtained in patients by means of skin window method, which is traumatic, or by examining venous blood. However, it is difficult to discern parameters of the local immune response in venous blood samples. We have attempted to find an adequate method which would be convenient both for the patient and for the researcher, in order to assess local immune processes occurring in the skin affected by psoriasis. We examined 20 patients with a verified diagnosis of psoriasis, the average age was 44.3 years. The control group included 15 healthy adults, with average age of 46.6 years. Capillary blood was taken by fingerprick, whereas, in psoriatic patients, the samples were taken near the psoriatic lesion at a final volume of 400 μL in two microvettes. Venous blood (3 mL) was taken from the cubital vein into a vacuum tube with EDTA. Clinical analysis of venous and capillary blood was performed in automated hematological analyzer. Immunophenotyping was performed by four-color staining of whole capillary and venous blood followed by lysis of erythrocytes. Cytofluorometry was performed using techniques and reagents from BD Biosciences (USA). Plasma cytokines were determined by multiplex approach (MagPix, BioRad, USA). Upon clinical analysis of blood, the difference between capillary and venous blood was not found, either in healthy group, or among patients with psoriasis. In healthy people, the subsets of mononuclear cells, did not differ between venous and capillary blood. The samples of capillary and venous blood in the patients with psoriasis showed significantly increased levels of double-positive lymphocytes (CD45RA+/CD45R0+), B lymphocytes and NKT lymphocytes (both for relative and and absolute values). A significant increase in the percentage of naive T lymphocytes, activated helpers (Thact) and Treg, as well as B1 cells and Breg, and a significant decrease in B2 lymphocytes was registered in capillary blood of the patients with psoriasis. In venous blood samples from psoriatic patients, only a significant increase in Thact, Treg, and Breg was revealed. In the capillary blood of patients with psoriasis, we found a significant increase in the levels of non-classical M2 monocytes and inflammatory Minfl monocytes, and a decrease in classical M1 monocyte levels; in venous blood of psoriatic patients, only an increase in inflammatory Minfl monocytes was revealed. In capillary blood, all the studied cytokines in psoriasis patients significantly exceeded the levels of corresponding cytokines in healthy controls, except of IL-10. The levels of this cytokine did not differ from healthy group. In venous blood, the levels of most studied cytokines in the group of patients with psoriasis did not differ from the group of healthy ones. Approximately two-fold increase was revealed for IL-4, IL-21, IL-23 and TNF. First, the subsets of mononuclear cells and the cytokine profile of capillary and venous blood of healthy people did not differ significantly. Secondly, our proposed method for determining the subsets of mononuclear cells and capillary blood cytokines profile from the area of psoriatic lesions may be used to monitor local immunity in the patients with psoriasis. This approach is significantly less traumatic than the skin window method and more informative than the studies of venous blood

Polymorphism of genes-candidates and ehokardiographic indicators at pregnant women in norm and at preeklampsia

Research about interrelation of some ehokardiographic indicators of heart with polymorphic markers of genes angiotensinogen (-6A/G AGT) and chimasa (-1903 G/A СМА) at pregnant women is conducted at preeklampsia. Polymorphism associations -1903 G/A СМА and -6A/G AGT with increase final diastolic left ventricular at pregnant women are found the size at preeklampsia