Bounded Emotionality and Polygamous Tradition in an Entrepreneurial Family Businesses in Nigeria

The goal of this paper is to examine bounded emotionality and polygamous tradition in an entrepreneurial family business in Nigeria. We argue that it is essential to consider culture of polygamy among family firms especially in the south west Nigeria. The multiple case method was used to provide valuable insights into entrepreneurial family businesses in Nigeria. To achieve better results, cases were drawn from diverse business sectors like merchandising, manufacturing and consultancy services among the family firms in South West, Nigeria. The paper analyses the limit of bounded emotionality, impact of nepotism and family ties in the polygamous family businesses. The findings reveal that the polygamous tradition has being in existence mostly in Africa for decades, hence, it brings some degree of sensitivity and unison to the family business. Finally, the paper demonstrates the importance of conducting further research on the concept of polygamy in Africa and tis impact on the family business

Strength Properties of Steel and Bamboo Reinforced Concrete Containing Quarry Dust, Rice Husk Ash and Guinea Corn Husk Ash

The rising cost of concrete production due to the global recession in world economy caused by the COVID-19 pandemic and the greenhouse gases emitted in the production of cement has necessitated the need for alternative materials for cement. In this study, bamboo strips and steel rebars were used as reinforcements in a ternary blended concrete to determine their strength properties. In alignment with standard requirements for testing, concrete specimens were tested at curing ages of 7, 14 and 28 days for compressive, splitting tensile and flexural strengths. The morphological and bond characteristics of the bamboo were determined through the Scanning Electron Microscopy (SEM) and Fourier Transform Infra-Red Spectroscopy (FTIR), respectively; while its tensile strength was determined and compared with that of steel reinforcement. These results showed that bamboo is ductile and has stretching vibrational spectrum. The combinations of quarry dust, river sand, Rice Husk Ash (RHA) and Guinea Corn Husk Ash (GCHA) yielded compressive and split tensile strengths of 20.4 N/mm2 and 2.18 N/mm2, respectively. Concrete with 50 % river sand and 50 % quarry dust performed better in flexure for both Bamboo Reinforced Concrete (BRC) and Steel Reinforced Concrete (SRC) at 28 days with strengths of 12.75 N/mm2 and 22.49 N/mm2, respectively. Therefore, bamboo, quarry dust, rice husk and guinea corn husk ash can be used for reinforced concrete production

Distinct monkeypox virus lineages co-circulating in humans before 2022

The 2022 global mpox outbreak raises questions about how this zoonotic disease established effective human-to-human transmission and its potential for further adaptation. The 2022 outbreak virus is related to an ongoing outbreak in Nigeria originally reported in 2017, but the evolutionary path linking the two remains unclear due to a lack of genomic data between 2018, when virus exportations from Nigeria were first recorded, and 2022, when the global mpox outbreak began. Here, 18 viral genomes obtained from patients across southern Nigeria in 2019-2020 reveal multiple lineages of monkeypox virus (MPXV) co-circulated in humans for several years before 2022, with progressive accumulation of mutations consistent with APOBEC3 activity over time. We identify Nigerian A.2 lineage isolates, confirming the lineage that has been multiply exported to North America independently of the 2022 outbreak originated in Nigeria, and that it has persisted by human-to-human transmission in Nigeria for more than 2 years before its latest exportation. Finally, we identify a lineage-defining APOBEC3-style mutation in all A.2 isolates that disrupts gene A46R, encoding a viral innate immune modulator. Collectively, our data demonstrate MPXV capacity for sustained diversification within humans, including mutations that may be consistent with established mechanisms of poxvirus adaptation.</p

Exportation of Monkeypox Virus From the African Continent.

BACKGROUND: The largest West African monkeypox outbreak began September 2017, in Nigeria. Four individuals traveling from Nigeria to the United Kingdom (n = 2), Israel (n = 1), and Singapore (n = 1) became the first human monkeypox cases exported from Africa, and a related nosocomial transmission event in the United Kingdom became the first confirmed human-to-human monkeypox transmission event outside of Africa. METHODS: Epidemiological and molecular data for exported and Nigerian cases were analyzed jointly to better understand the exportations in the temporal and geographic context of the outbreak. RESULTS: Isolates from all travelers and a Bayelsa case shared a most recent common ancestor and traveled to Bayelsa, Delta, or Rivers states. Genetic variation for this cluster was lower than would be expected from a random sampling of genomes from this outbreak, but data did not support direct links between travelers. CONCLUSIONS: Monophyly of exportation cases and the Bayelsa sample, along with the intermediate levels of genetic variation, suggest a small pool of related isolates is the likely source for the exported infections. This may be the result of the level of genetic variation present in monkeypox isolates circulating within the contiguous region of Bayelsa, Delta, and Rivers states, or another more restricted, yet unidentified source pool

Epidemiology, diagnostics and factors associated with mortality during a cholera epidemic in Nigeria, October 2020-October 2021: a retrospective analysis of national surveillance data.

OBJECTIVES: Nigeria reported an upsurge in cholera cases in October 2020, which then transitioned into a large, disseminated epidemic for most of 2021. This study aimed to describe the epidemiology, diagnostic performance of rapid diagnostic test (RDT) kits and the factors associated with mortality during the epidemic. DESIGN: A retrospective analysis of national surveillance data. SETTING: 33 of 37 states (including the Federal Capital Territory) in Nigeria. PARTICIPANTS: Persons who met cholera case definition (a person of any age with acute watery diarrhoea, with or without vomiting) between October 2020 and October 2021 within the Nigeria Centre for Disease Control surveillance data. OUTCOME MEASURES: Attack rate (AR; per 100 000 persons), case fatality rate (CFR; %) and accuracy of RDT performance compared with culture using area under the receiver operating characteristic curve (AUROC). Additionally, individual factors associated with cholera deaths and hospitalisation were presented as adjusted OR with 95% CIs. RESULTS: Overall, 93 598 cholera cases and 3298 deaths (CFR: 3.5%) were reported across 33 of 37 states in Nigeria within the study period. The proportions of cholera cases were higher in men aged 5-14 years and women aged 25-44 years. The overall AR was 46.5 per 100 000 persons. The North-West region recorded the highest AR with 102 per 100 000. Older age, male gender, residency in the North-Central region and severe dehydration significantly increased the odds of cholera deaths. The cholera RDT had excellent diagnostic accuracy (AUROC=0.91; 95% CI 0.87 to 0.96). CONCLUSIONS: Cholera remains a serious public health threat in Nigeria with a high mortality rate. Thus, we recommend making RDT kits more widely accessible for improved surveillance and prompt case management across the country

Emergence and spread of two SARS-CoV-2 variants of interest in Nigeria.

Identifying the dissemination patterns and impacts of a virus of economic or health importance during a pandemic is crucial, as it informs the public on policies for containment in order to reduce the spread of the virus. In this study, we integrated genomic and travel data to investigate the emergence and spread of the SARS-CoV-2 B.1.1.318 and B.1.525 (Eta) variants of interest in Nigeria and the wider Africa region. By integrating travel data and phylogeographic reconstructions, we find that these two variants that arose during the second wave in Nigeria emerged from within Africa, with the B.1.525 from Nigeria, and then spread to other parts of the world. Data from this study show how regional connectivity of Nigeria drove the spread of these variants of interest to surrounding countries and those connected by air-traffic. Our findings demonstrate the power of genomic analysis when combined with mobility and epidemiological data to identify the drivers of transmission, as bidirectional transmission within and between African nations are grossly underestimated as seen in our import risk index estimates

Occurrence of otitis media in children and assessment of treatment options

Background: Otitis media is a more frequent occurrence in children, and the disease may progress from an acute to chronic state if appropriate and timely intervention is not initiated. Methods: A total of 212 children aged 6 months to 10 years were examined and treated for otitis media, in a 13-month hospital-based study. Results: Acute otitis media was diagnosed in 130 (61.3 per cent) of the patients. There were 82 (38.7 per cent) chronic suppurative otitis media cases. The incidence of acute otitis media and chronic suppurative otitis media in the first year of life was 54.6 per cent and 45.1 per cent respectively. Chronic suppurative otitis media patients were assigned to one of three treatment groups. Recovery occurred in 70.4 per cent of amoxicillin-treated patients, in 88.9 per cent of amoxicillin-clavulanic acid treated patients and in 96.4 per cent of culture and antibiotic sensitivity test patients. Relapses were seen only in the amoxicillin (five cases) and amoxicillin-clavulanic acid (two cases) groups. Conclusion: The success rate in patients treated with antibiotics makes this option mandatory for an established diagnosis